Nguyễn Thụy Thương Thương
YOU?
Author Swipe
View article: Strain diversity drives heterogeneous responses to tuberculosis combination therapy
Strain diversity drives heterogeneous responses to tuberculosis combination therapy Open
Background: Strain diversity in Mycobacterium tuberculosis (Mtb) underlies distinct clinical presentations and outcomes, but the range of drug susceptibility phenotypes among clinical isolates is poorly understood. We aimed to identify dru…
View article: KIẾN THỨC BẢN ĐỊA CỦA NGƯỜI CƠ TU TRONG QUẢN LÝ VÀ PHÁT TRIỂN BỀN VỮNG LOÀI MÂY NƯỚC MỠ (CALAMUS SP.) Ở HUYỆN ĐÔNG GIANG VÀ NAM GIANG, TỈNH QUẢNG NAM
KIẾN THỨC BẢN ĐỊA CỦA NGƯỜI CƠ TU TRONG QUẢN LÝ VÀ PHÁT TRIỂN BỀN VỮNG LOÀI MÂY NƯỚC MỠ (CALAMUS SP.) Ở HUYỆN ĐÔNG GIANG VÀ NAM GIANG, TỈNH QUẢNG NAM Open
Đông Giang và Nam Giang là hai huyện miền núi nằm ở phía Tây Bắc của tỉnh Quảng Nam. Tại khu vực này, người dân địa phương đã ghi nhận sự xuất hiện của loài Mây nước mỡ trong tự nhiên. Mây nước mỡ là loài cây lâm sản ngoài gỗ, mang lại ngu…
View article: Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance
Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance Open
Mycobacterium tuberculosis (Mtb) has co-evolved with humans for thousands of years and is characterized by variation in virulence, transmissibility, and disease phenotypes. To identify bacterial contributors to phenotypic diversity, we dev…
View article: Single-cell profiling of blood and cerebrospinal fluid in tuberculous meningitis
Single-cell profiling of blood and cerebrospinal fluid in tuberculous meningitis Open
Tuberculous meningitis (TBM) is the most severe form of tuberculosis, with a fatality rate of 20% to 50% in treated individuals. Although corticosteroid therapy can increase survival in HIV-negative people with TBM, better antimicrobial an…
View article: Brain Imaging and Whole Blood Targeted Transcriptomic Analyses to Characterize Cerebral Infarctions in Children With Tuberculous Meningitis
Brain Imaging and Whole Blood Targeted Transcriptomic Analyses to Characterize Cerebral Infarctions in Children With Tuberculous Meningitis Open
We characterized cerebral infarction in children with tuberculous meningitis and explored its relationship with systemic inflammatory mediators using targeted transcriptomic analysis. Children with tuberculous meningitis had baseline magne…
View article: Increased proportion of growth-arrested bacilli in acidic pH adaptation promotes <i>Mycobacterium tuberculosis</i> treatment survival
Increased proportion of growth-arrested bacilli in acidic pH adaptation promotes <i>Mycobacterium tuberculosis</i> treatment survival Open
The ability of Mycobacterium tuberculosis (Mtb) to adapt its growth behavior in response to host environments promotes survival against immune and drug stressors. However, how these behaviors shift at the single-cell level remains poorly u…
View article: 42. THE SATISFACTION OF INPATIENTS WITH THE USE OF MEDICAL SERVICES AT TAM DAO DISTRICT MEDICAL CENTER, VINH PHUC PROVINCE, IN 2024.
42. THE SATISFACTION OF INPATIENTS WITH THE USE OF MEDICAL SERVICES AT TAM DAO DISTRICT MEDICAL CENTER, VINH PHUC PROVINCE, IN 2024. Open
Objectives: Assessment of inpatients' satisfaction with medical services in clinical departments at Tam Dao District Medical Center in 2024. Method: Cross-sectional descriptive study. Results: The study, conducted on 218 participants at Ta…
View article: Organizational Management Behavior of Small and Medium Enterprises in Vietnam in the Context of Digital Transformation: Issues and Strategic Solutions
Organizational Management Behavior of Small and Medium Enterprises in Vietnam in the Context of Digital Transformation: Issues and Strategic Solutions Open
This article examines the current state of organizational management behavior in small and medium-sized enterprises (SMEs) in Vietnam amid the ongoing transition to a market-oriented economy and the acceleration of digital transformation. …
View article: Pre-treatment untargeted cerebrospinal fluid metabolomic profiling in tuberculous meningitis uncovers pathways associated with mortality
Pre-treatment untargeted cerebrospinal fluid metabolomic profiling in tuberculous meningitis uncovers pathways associated with mortality Open
National Institute of Health; Wellcome Trust, UK.
View article: Convolutional neural network using magnetic resonance brain imaging to predict outcome from tuberculosis meningitis
Convolutional neural network using magnetic resonance brain imaging to predict outcome from tuberculosis meningitis Open
Introduction Tuberculous meningitis (TBM) leads to high mortality, especially amongst individuals with HIV. Predicting the incidence of disease-related complications is challenging, for which purpose the value of brain magnetic resonance i…
View article: Myeloid cell genome-wide screen identifies variants associated with Mycobacterium tuberculosis–induced cytokine transcriptional responses
Myeloid cell genome-wide screen identifies variants associated with Mycobacterium tuberculosis–induced cytokine transcriptional responses Open
Immune and clinical outcomes to Mycobacterium tuberculosis (Mtb) infection vary greatly between individuals, yet the underlying genetic and cellular mechanisms driving this heterogeneity remain poorly understood. We performed a cellular ge…
View article: Fatal Mycobacterium avium meningitis in an HIV-negative Vietnamese man: a case report
Fatal Mycobacterium avium meningitis in an HIV-negative Vietnamese man: a case report Open
View article: Evolution of <i>Mycobacterium tuberculosis</i> transcription regulation is associated with increased transmission and drug resistance
Evolution of <i>Mycobacterium tuberculosis</i> transcription regulation is associated with increased transmission and drug resistance Open
Summary Mycobacterium tuberculosis (Mtb) has co-evolved with humans for thousands of years causing variation in virulence, transmissibility, and disease phenotypes. To identify bacterial contributors to phenotypic diversity, we developed n…
View article: Đặc điểm kháng colistin của các chủng Klebsiella pneumoniae phân lập từ các hộ chăn nuôi khu vực Nam Định năm 2023
Đặc điểm kháng colistin của các chủng Klebsiella pneumoniae phân lập từ các hộ chăn nuôi khu vực Nam Định năm 2023 Open
Klebsiella pneumoniae là một trong các tác nhân hàng đầu gây nhiễm trùng cơ hội trên người, với khả năng đề kháng nhiều loại kháng sinh, được tìm thấy trong môi trường, hệ đường ruột của người, động vật. Gene đề kháng colistin mcr-1 và mcr…
View article: Single-cell profiling of blood and cerebrospinal fluid in tuberculous meningitis
Single-cell profiling of blood and cerebrospinal fluid in tuberculous meningitis Open
Tuberculous meningitis (TBM) is the most severe form of tuberculosis, with a fatality rate of 20-50% in treated individuals. Although corticosteroid therapy can increase survival in HIV-negative people with TBM, better antimicrobial and ho…
View article: Performance of 2 Finger-Stick Blood Tests to Triage Adults With Symptoms of Pulmonary Tuberculosis: A Prospective Multisite Diagnostic Accuracy Study
Performance of 2 Finger-Stick Blood Tests to Triage Adults With Symptoms of Pulmonary Tuberculosis: A Prospective Multisite Diagnostic Accuracy Study Open
Background Non–sputum-based, point-of-care triage tests for pulmonary tuberculosis could enhance tuberculosis diagnostic programs. We assessed the diagnostic accuracy of 2 finger-stick blood tests: the Cepheid 3 gene host-response cartridg…
View article: A modified decontamination and storage method for sputum from patients with tuberculosis
A modified decontamination and storage method for sputum from patients with tuberculosis Open
Background Collecting and storing large number of sputum samples with a view to culturing these in the future requires an efficient initial handling method. We devised a modified sputum digestion and decontamination method that maximised s…
View article: Statistical analysis plan for the LAST ACT clinical trial; a Leukotriene A4 hydrolase Stratified non-inferiority Trial of Adjunctive Corticosteroids for HIV-negative adults with Tuberculous meningitis
Statistical analysis plan for the LAST ACT clinical trial; a Leukotriene A4 hydrolase Stratified non-inferiority Trial of Adjunctive Corticosteroids for HIV-negative adults with Tuberculous meningitis Open
Tuberculous meningitis (TBM) is the most severe form of tuberculosis. Corticosteroids are currently recommended as an adjunctive therapy in HIV-negative adults with TBM. However, benefit from corticosteroids in TBM may depend upon host leu…
View article: Statistical analysis plan for the LAST ACT clinical trial; a Leukotriene A4 hydrolase Stratified non-inferiority Trial of Adjunctive Corticosteroids for HIV-negative adults with Tuberculous meningitis
Statistical analysis plan for the LAST ACT clinical trial; a Leukotriene A4 hydrolase Stratified non-inferiority Trial of Adjunctive Corticosteroids for HIV-negative adults with Tuberculous meningitis Open
Tuberculous meningitis (TBM) is the most severe form of tuberculosis. Corticosteroids are currently recommended as an adjunctive therapy in HIV-negative adults with TBM. However, benefit from corticosteroids in TBM may depend upon host le…
View article: 17. ANXIETY IN POST-CAESAREAN MOTHERS AT VINMEC TIMES CITY INTERNATIONAL GENERAL HOSPITAL IN 2024 AND RELATED FACTORS
17. ANXIETY IN POST-CAESAREAN MOTHERS AT VINMEC TIMES CITY INTERNATIONAL GENERAL HOSPITAL IN 2024 AND RELATED FACTORS Open
Objectives: This study aims to describe the anxiety status of post-caesarean mothers at Vinmec Times City International Hospital, Hanoi, in 2024, and analyze related factors. Methods: A cross-sectional descriptive study was conducted with …
View article: Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis
Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis Open
Mortality and morbidity from tuberculous meningitis (TBM) are common, primarily due to inflammatory response to Mycobacterium tuberculosis infection, yet the underlying mechanisms remain poorly understood. We aimed to uncover genes and pat…
View article: Advancing the chemotherapy of tuberculous meningitis: a consensus view
Advancing the chemotherapy of tuberculous meningitis: a consensus view Open
View article: A description of lineage 1 Mycobacterium tuberculosis from papua, Indonesia
A description of lineage 1 Mycobacterium tuberculosis from papua, Indonesia Open
\n Contains fulltext :\n 311216.pdf (Publisher’s version ) (Open Access)\n
View article: Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates from a longitudinal study
Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates from a longitudinal study Open
Antibiotic tolerance in Mycobacterium tuberculosis reduces bacterial killing, worsens treatment outcomes, and contributes to resistance. We studied rifampicin tolerance in isolates with or without isoniazid resistance (IR). Using a minimum…
View article: Correction: The effect of M. tuberculosis lineage on clinical phenotype
Correction: The effect of M. tuberculosis lineage on clinical phenotype Open
[This corrects the article DOI: 10.1371/journal.pgph.0001788.].
View article: Computer-aided prognosis of tuberculous meningitis combining imaging and non-imaging data
Computer-aided prognosis of tuberculous meningitis combining imaging and non-imaging data Open
Tuberculous meningitis (TBM) is the most lethal form of tuberculosis. Clinical features, such as coma, can predict death, but they are insufficient for the accurate prognosis of other outcomes, especially when impacted by co-morbidities su…
View article: Author response: Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates: an in-vitro longitudinal study
Author response: Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates: an in-vitro longitudinal study Open
Antibiotic tolerance in Mycobacterium tuberculosis leads to less effective bacterial killing, poor treatment responses and resistant emergence. Therefore, we investigated the rifampicin tolerance of M. tuberculosis isolates, with or withou…
View article: Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates: an in-vitro longitudinal study
Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates: an in-vitro longitudinal study Open
Antibiotic tolerance in Mycobacterium tuberculosis leads to less effective bacterial killing, poor treatment responses and resistant emergence. Therefore, we investigated the rifampicin tolerance of M. tuberculosis isolates, with or withou…
View article: The implementation of whole-genome sequencing for <i>Mycobacterium tuberculosis</i> in Vietnam
The implementation of whole-genome sequencing for <i>Mycobacterium tuberculosis</i> in Vietnam Open
View article: Detection of co-infection and recombination cases with Omicron and local Delta variants of SARS-CoV-2 in Vietnam
Detection of co-infection and recombination cases with Omicron and local Delta variants of SARS-CoV-2 in Vietnam Open
The first nationwide outbreak of COVID-19 in Vietnam started in late April 2021 and was caused almost exclusively by a single Delta lineage, AY.57. In early 2022, multiple Omicron variants co-circulated with Delta variants and quickly beca…