Niamh Dooley
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View article: Cybervictimisation and mental health conditions in young people: findings from a nationally representative longitudinal cohort
Cybervictimisation and mental health conditions in young people: findings from a nationally representative longitudinal cohort Open
View article: Engagement and retention with remote monitoring in psoriasis: Findings from the <scp>mySkin</scp> study
Engagement and retention with remote monitoring in psoriasis: Findings from the <span>mySkin</span> study Open
View article: PLAN-psoriasis: protocol for a randomised controlled feasibility trial comparing patient-led ‘as-needed’ treatment and therapeutic drug monitoring-guided treatment to continuous treatment for adults with clear or almost clear skin on risankizumab monotherapy for psoriasis
PLAN-psoriasis: protocol for a randomised controlled feasibility trial comparing patient-led ‘as-needed’ treatment and therapeutic drug monitoring-guided treatment to continuous treatment for adults with clear or almost clear skin on risankizumab monotherapy for psoriasis Open
Introduction Targeted biologic therapies have transformed outcomes for individuals with psoriasis, a common immune-mediated inflammatory skin disease. The widespread use of these highly effective treatments has led to a growing number of i…
View article: P004 Temporal and regional variation in the initiation of biologic and targeted synthetic DMARDs for rheumatoid arthritis: a nationwide cohort study
P004 Temporal and regional variation in the initiation of biologic and targeted synthetic DMARDs for rheumatoid arthritis: a nationwide cohort study Open
Background/Aims For people who have active rheumatoid arthritis (RA) despite treatment with conventional synthetic DMARDs, timely escalation to biologic and targeted synthetic DMARDs (b/tsDMARDs) improves outcomes and prevents morbidity. I…
View article: P058 Characterising rheumatoid arthritis impact of disease (RAID) profiles and variability in patients with rheumatoid arthritis
P058 Characterising rheumatoid arthritis impact of disease (RAID) profiles and variability in patients with rheumatoid arthritis Open
Background/Aims Rheumatoid arthritis (RA) is an idiopathic inflammatory arthritis. Monitoring disease activity is essential for effective management, with patient-reported outcome measures (PROMs) gaining prominence in assessing symptom bu…
View article: Evaluating a digital mental health intervention for people with Parkinson’s (PACT): acceptability and feasibility randomised controlled trial
Evaluating a digital mental health intervention for people with Parkinson’s (PACT): acceptability and feasibility randomised controlled trial Open
Progression criteria were met, and PACT was acceptable to people with Parkinson's. It has potential efficacy and cost-effectiveness. A future larger trial to fully evaluate efficacy is needed.Trial registration: ISRCTN65177345 (01/09/2023).
View article: Environmental triggers of psoriasis: insights from a UK patient-reported cohort (mySkin)
Environmental triggers of psoriasis: insights from a UK patient-reported cohort (mySkin) Open
We developed mySkin, an online platform that captures self-reported information from people with psoriasis across the UK, to improve our knowledge on the environmental determinants of psoriasis. In this cross-sectional analysis of the firs…
View article: <b>Risk and protective factors for cannabis use in adolescence: a population-based survey in schools</b>
<b>Risk and protective factors for cannabis use in adolescence: a population-based survey in schools</b> Open
Background: Cannabis is the most commonly used illicit substance in Ireland and globally. It is most likely to be used in adolescence, a period of biopsychosocial vulnerability to maladaptive behaviours. This study aims to investigate the …
View article: Temporal and regional variation in the use of biologic and targeted synthetic DMARDs for rheumatoid arthritis: a nationwide cohort study
Temporal and regional variation in the use of biologic and targeted synthetic DMARDs for rheumatoid arthritis: a nationwide cohort study Open
Objective The objective of this study was to evaluate temporal and regional variation in biologic and targeted synthetic DMARD (b/tsDMARD) initiation for RA in England and Wales. Methods An observational cohort study was conducted for peop…
View article: Paclitaxel- or sirolimus-coated balloons used for ArterioVEnous fistulas-2 (PAVE-2): study protocol for a randomised controlled trial to determine the efficacy of paclitaxel- or sirolimus-coated balloons in arteriovenous fistulas used for haemodialysis
Paclitaxel- or sirolimus-coated balloons used for ArterioVEnous fistulas-2 (PAVE-2): study protocol for a randomised controlled trial to determine the efficacy of paclitaxel- or sirolimus-coated balloons in arteriovenous fistulas used for haemodialysis Open
View article: Mental health of Irish adolescents following the COVID-19 pandemic: results from a population-based cross-sectional survey
Mental health of Irish adolescents following the COVID-19 pandemic: results from a population-based cross-sectional survey Open
Objectives: This study provides data on the prevalence of mental health problems among adolescents in Ireland in 2021, toward the end of the COVID-19 pandemic. The importance of having recent, large-scale, mental health data for adolescent…
View article: Pregnancy complications and childhood mental health: is the association modified by sex or adverse social circumstances? Findings from the ‘growing up in Ireland’ national infant cohort study
Pregnancy complications and childhood mental health: is the association modified by sex or adverse social circumstances? Findings from the ‘growing up in Ireland’ national infant cohort study Open
Specific pregnancy complications, socioeconomic position and sex have all been independently associated with child mental health outcomes, but their combined effects remain unclear. We examined whether total number of complications experie…
View article: Examining the association between prenatal and perinatal adversity and the psychotic experiences in childhood
Examining the association between prenatal and perinatal adversity and the psychotic experiences in childhood Open
Background Prenatal and perinatal complications are established risk factors for psychotic disorder, but far less is known about these measures and psychotic experiences (PEs). We investigated the longitudinal effect of prenatal risk facto…
View article: The long shadow of childhood mental health problems
The long shadow of childhood mental health problems Open
The long shadow of childhood mental health problems Dr Niamh Dooley and Professor Mary Cannon explore what young adult life looks like for individuals who had mental health problems as children. People who suffer with their mental health i…
View article: Longitudinal hippocampal subfield development associated with psychotic experiences in young people
Longitudinal hippocampal subfield development associated with psychotic experiences in young people Open
View article: Trajectories of psychopathology among young people related to outcomes in young adulthood
Trajectories of psychopathology among young people related to outcomes in young adulthood Open
What does young adulthood look like for individuals who had mental health problems across childhood? Using the Growing Up in Ireland cohort (born in 1998 and studied from ages 9 to 20) we explored the association between mental health prob…
View article: Correlates of psychotic experiences in gender-diverse youth in Ireland: A population-based survey
Correlates of psychotic experiences in gender-diverse youth in Ireland: A population-based survey Open
Epidemiological studies have shown that psychotic disorders are more prevalent in transgender and non-binary (TR/NB) individuals compared to their cisgender (i.e., male & female) counterparts (CIS). Despite this, little research exists tha…
View article: Mental health and suicidal behaviours among Irish adolescents - results from the Planet Youth study
Mental health and suicidal behaviours among Irish adolescents - results from the Planet Youth study Open
Mental health and wellbeing outcomes for young people are poorly understood in the context of natural disasters. There is a little high-quality evidence at a population level describing mental health and wellbeing in young people in Irelan…
View article: Functional Outcomes Among Young People With Trajectories of Persistent Childhood Psychopathology
Functional Outcomes Among Young People With Trajectories of Persistent Childhood Psychopathology Open
Importance Understanding which children in the general population are at greatest risk of poor functional outcomes could improve early screening and intervention strategies. Objective To investigate the odds of poor outcomes in emerging ad…
View article: Longitudinal hippocampal subfield development associated with psychotic experiences in young people
Longitudinal hippocampal subfield development associated with psychotic experiences in young people Open
Hippocampal volumetric reductions are observed across the psychosis spectrum, with interest in the localisation of these reductions within the hippocampal subfields increasing. Deficits of the CA1 subfield in particular have been implicate…
View article: Predicting childhood ADHD-linked symptoms from prenatal and perinatal data in the ABCD cohort
Predicting childhood ADHD-linked symptoms from prenatal and perinatal data in the ABCD cohort Open
This study investigates the capacity of pre/perinatal factors to predict attention-deficit/hyperactivity disorder (ADHD) symptoms in childhood. It also explores whether predictive accuracy of a pre/perinatal model varies for different grou…
View article: Explaining the Association Between Fetal Growth and Childhood ADHD Symptoms: Cross-cohort Replication
Explaining the Association Between Fetal Growth and Childhood ADHD Symptoms: Cross-cohort Replication Open
View article: The persistent effects of foetal growth on child and adolescent mental health: longitudinal evidence from a large population-based cohort
The persistent effects of foetal growth on child and adolescent mental health: longitudinal evidence from a large population-based cohort Open
View article: Prediction of ADHD symptoms from prenatal data in two large population-based cohorts
Prediction of ADHD symptoms from prenatal data in two large population-based cohorts Open
Introduction The association between low birth weight and attention problems in childhood has been replicated many times (e.g. Momany, Kamradt, & Nikolas, 2018). However birth weight is unlikely the aetiological start-point of this associa…
View article: Person-Centered Trajectories of Psychopathology From Early Childhood to Late Adolescence
Person-Centered Trajectories of Psychopathology From Early Childhood to Late Adolescence Open
Using person-centered methods, this study demonstrated that from early life young peoples' experience of psychopathology is dynamic-they can move between different mental health problems; for most children, these problems are transient, bu…
View article: Longitudinal Gray Matter Development Associated With Psychotic Experiences in Young People
Longitudinal Gray Matter Development Associated With Psychotic Experiences in Young People Open
These findings further implicate right hippocampal volumetric abnormalities in the pathophysiology underlying PEs. Furthermore, as suggested by previous studies in those at clinical high risk for psychosis and those with first-episode psyc…
View article: Birth Weight and Childhood Psychopathology in the ABCD Cohort: Association is Strongest for Attention Problems and is Moderated by Sex
Birth Weight and Childhood Psychopathology in the ABCD Cohort: Association is Strongest for Attention Problems and is Moderated by Sex Open
Many studies have shown low birth weight is associated with psychopathology later in life, particularly attention-deficit/hyperactivity disorder (ADHD). The association is well-replicated, independent from a variety of potential familial c…
View article: Neuroanatomical markers of psychotic experiences in adolescents: A machine-learning approach in a longitudinal population-based sample
Neuroanatomical markers of psychotic experiences in adolescents: A machine-learning approach in a longitudinal population-based sample Open
View article: Is there an association between prenatal testosterone and autistic traits in adolescents?
Is there an association between prenatal testosterone and autistic traits in adolescents? Open
Prenatal testosterone (pT) is a crucial component in physiological masculinization in humans. In line with the Prenatal Sex Steroid Theory of autism, some studies have found a positive correlation between pT and autistic traits in childhoo…
View article: Prevalence of DSM-V mental disorders in a cohort of young adults in Ireland
Prevalence of DSM-V mental disorders in a cohort of young adults in Ireland Open
Aims To estimate the prevalence of DSM-V mental disorders in a population of Irish emerging adults Background Mental disorders are the leading cause of years lived with disability in youth worldwide. Few studies use gold standard of face t…