Nicholas Cardillo
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View article: scRNA-seq Can Identify Different Cell Populations in Ovarian Cancer Bulk RNA-seq Experiments
scRNA-seq Can Identify Different Cell Populations in Ovarian Cancer Bulk RNA-seq Experiments Open
High-grade serous ovarian cancer (HGSC) is a heterogeneous disease. RNA sequencing (RNAseq) of bulk solid tissue is of limited use in these populations due to heterogeneity. Single-cell RNA-seq (scRNA-seq) allows for the identification of …
View article: Vaginal lacerations during laparoscopic hysterectomy for endometrial cancer and local recurrence risk
Vaginal lacerations during laparoscopic hysterectomy for endometrial cancer and local recurrence risk Open
View article: Using Genomic Variation to Distinguish Ovarian High-Grade Serous Carcinoma from Benign Fallopian Tubes
Using Genomic Variation to Distinguish Ovarian High-Grade Serous Carcinoma from Benign Fallopian Tubes Open
The preoperative diagnosis of pelvic masses has been elusive to date. Methods for characterization such as CA-125 have had limited specificity. We hypothesize that genomic variation can be used to create prediction models which accurately …
View article: Integrated Clinical and Genomic Models to Predict Optimal Cytoreduction in High-Grade Serous Ovarian Cancer
Integrated Clinical and Genomic Models to Predict Optimal Cytoreduction in High-Grade Serous Ovarian Cancer Open
Advanced high-grade serous (HGSC) ovarian cancer is treated with either primary surgery followed by chemotherapy or neoadjuvant chemotherapy followed by interval surgery. The decision to proceed with surgery primarily or after chemotherapy…
View article: Investigating the effect of optimal cytoreduction in the context of platinum sensitivity in high‐grade serous ovarian cancer
Investigating the effect of optimal cytoreduction in the context of platinum sensitivity in high‐grade serous ovarian cancer Open
Introduction The survival benefits of surgical cytoreduction in ovarian cancer are well‐established. However, the surgical outcome has never been assessed while controlling for the efficacy of chemotherapy. This leaves the possibility that…
View article: Disparity of ovarian cancer survival between urban and rural settings
Disparity of ovarian cancer survival between urban and rural settings Open
View article: Integrated Clinical and Genomic Models to Predict Optimal Cytoreduction in High Grade Serous Ovarian Cancer
Integrated Clinical and Genomic Models to Predict Optimal Cytoreduction in High Grade Serous Ovarian Cancer Open
Background: Advanced high grade serous (HGSC) ovarian cancer is treated with either primary surgery followed by chemotherapy or neoadjuvant chemotherapy followed by interval surgery. The decision to proceed with surgery either primarily or…
View article: A nuclear polymorphism at the 8q24 region is associated with improved survival time and chemo‑response in high‑grade serous ovarian cancer
A nuclear polymorphism at the 8q24 region is associated with improved survival time and chemo‑response in high‑grade serous ovarian cancer Open
The 8q24 chromosomal region is strongly associated with an increased risk of ovarian cancer. One single nucleotide polymorphism that is associated with ovarian cancer in this region is rs6983267, located within the long non-coding RNA colo…
View article: Identification of Novel lncRNAs in Ovarian Cancer and Their Impact on Overall Survival
Identification of Novel lncRNAs in Ovarian Cancer and Their Impact on Overall Survival Open
Long non-coding RNA’s (lncRNA) are RNA sequences that do not encode proteins and are greater than 200 nucleotides in length. They regulate complex cellular mechanisms and have been associated with prognosis in various types of cancer. We a…
View article: At the Mercy of Monsters: Expressionism and Bram Stoker’s Dracula on the Stage
At the Mercy of Monsters: Expressionism and Bram Stoker’s Dracula on the Stage Open
It is from the Expressionistic style of theatre, first born out of pre-World War I tensions in Germany, that what we today associate with visual horror was first formed; film scholars suggesting that the horror movie as we know it was born…
View article: Focused clinical multi-disciplinary ISP final project: substance use disorder and PTSD
Focused clinical multi-disciplinary ISP final project: substance use disorder and PTSD Open
Multiple theories about the association between Post Traumatic Stress Disorder (PTSD) and Substance Use Disorder (SUD) have been proposed, but there is yet to be a common consensus on their exact relationship. Regardless of the etiology of…
View article: Clinical Impact of Local Progression in Pancreatic Cancer
Clinical Impact of Local Progression in Pancreatic Cancer Open
Background: The high prevalence of distant metastatic disease among patients with pancreatic cancer often draws attention away from the local pancreatic tumor. This study aimed to define the complications and hospitalizations from l…
View article: Retraction Notice to: A BLOC-1 Mutation Screen Reveals that PLDN Is Mutated in Hermansky-Pudlak Syndrome Type 9
Retraction Notice to: A BLOC-1 Mutation Screen Reveals that PLDN Is Mutated in Hermansky-Pudlak Syndrome Type 9 Open
View article: The Importance of Local Tumor Control in Pancreatic Cancer
The Importance of Local Tumor Control in Pancreatic Cancer Open