Nicholas E. Bollis
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View article: A Fast Neural Network for Isotopic Charge State Assignment
A Fast Neural Network for Isotopic Charge State Assignment Open
Electrospray ionization (ESI) mass spectrometry is an essential technique for chemical analysis in a range of fields. In ESI, analytes can produce multiple charge states, which must be correctly assigned for identification. Existing approa…
View article: A Fast Neural Network for Isotopic Charge State Assignment
A Fast Neural Network for Isotopic Charge State Assignment Open
Electrospray ionization (ESI) mass spectrometry is an essential technique for chemical analysis in a range of fields. In ESI, analytes can produce multiple charge states, which must be correctly assigned for identification. Existing approa…
View article: Spectral averaging with outlier rejection algorithms to increase identifications in top‐down proteomics
Spectral averaging with outlier rejection algorithms to increase identifications in top‐down proteomics Open
The identification of proteoforms by top‐down proteomics requires both high quality fragmentation spectra and the neutral mass of the proteoform from which the fragments derive. Intact proteoform spectra can be highly complex and may inclu…