Nicholas Goulet
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View article: Brain-derived neurotrophic factor in peripheral blood mononuclear cells from healthy adults following acute aerobic exercise and a 6-hour recovery in temperate and hot environments
Brain-derived neurotrophic factor in peripheral blood mononuclear cells from healthy adults following acute aerobic exercise and a 6-hour recovery in temperate and hot environments Open
Brain-derived neurotrophic factor (BDNF) supports cognitive function and is released into systemic circulation in response to exercise or heat exposure. However, the relationship between exercise- and heat-induced BDNF responses in periphe…
View article: The effect of an exercise- and passive-induced heat stress on autophagy in young and older males
The effect of an exercise- and passive-induced heat stress on autophagy in young and older males Open
We show that a short-duration (30-min) bout of vigorous-intensity exercise stimulates autophagy in young and older males when performed in a temperate environment. However, when exposed to an equivalent heat load as achieved during the pri…
View article: The combined impacts of toxic drug use and the 2021 Heat Dome in Canada: A thematic analysis of online news media articles
The combined impacts of toxic drug use and the 2021 Heat Dome in Canada: A thematic analysis of online news media articles Open
Introduction During the summer of 2021, western Canada experienced a historic and deadly extreme heat event. Simultaneously, toxic drug use and overdoses related to high-risk use of opioids and polysubstance use continued to rise across th…
View article: The effect of high-intensity exercise in temperate and hot ambient conditions on autophagy and the cellular stress response in young and older females
The effect of high-intensity exercise in temperate and hot ambient conditions on autophagy and the cellular stress response in young and older females Open
We show for the first time that an acute bout (30 min) of high-intensity intensity exercise stimulates autophagy in young females irrespective of ambient heat exposure. However, older females did not display the same increase in autophagy …
View article: Revisiting the effect of acute intermittent hypoxemia on postprandial triglyceride levels in healthy young men
Revisiting the effect of acute intermittent hypoxemia on postprandial triglyceride levels in healthy young men Open
View article: Changes in appetite during acute passive intermittent and continuous hypoxemia in postprandial and fasting states: A combined analysis of four laboratory-based randomized crossover trials
Changes in appetite during acute passive intermittent and continuous hypoxemia in postprandial and fasting states: A combined analysis of four laboratory-based randomized crossover trials Open
Hypoxemia occurs during exposure to high altitude (continuous hypoxemia) or in the context of breathing disorders such as obstructive sleep apnea (OSA; intermittent hypoxemia). Growing evidence demonstrates that hypoxemia induces an anorex…
View article: Beach day or deadly heatwave? Content analysis of media images from the 2021 Heat Dome in Canada
Beach day or deadly heatwave? Content analysis of media images from the 2021 Heat Dome in Canada Open
During extreme heat events (EHEs) the public often learns about health protective actions through the media. Visual news coverage can act as a powerful tool to help convey complex health protective actions to the public. Despite the import…
View article: Impaired autophagy following ex vivo cooling of simulated hypothermic temperatures in peripheral blood mononuclear cells from young and older adults
Impaired autophagy following ex vivo cooling of simulated hypothermic temperatures in peripheral blood mononuclear cells from young and older adults Open
Hypothermia is a critical consequence of extreme cold exposure that increases the risk of cold-related injury and death in humans. While the initiation of cytoprotective mechanisms including the process of autophagy and the heat shock resp…
View article: “Death Is a Possibility for Those without Shelter”: A Thematic Analysis of News Coverage on Homelessness and the 2021 Heat Dome in Canada
“Death Is a Possibility for Those without Shelter”: A Thematic Analysis of News Coverage on Homelessness and the 2021 Heat Dome in Canada Open
Among the most vulnerable to the health-harming effects of heat are people experiencing homelessness. However, during the 2021 Heat Dome, the deadliest extreme heat event (EHE) recorded in Canada to date, people experiencing homelessness r…
View article: “Breaking down in tears, soaked in sweat, and sick from the heat”: Media‐based composite narratives of first responders working during the 2021 Heat Dome
“Breaking down in tears, soaked in sweat, and sick from the heat”: Media‐based composite narratives of first responders working during the 2021 Heat Dome Open
Background During the summer of 2021, a deadly, unprecedented multiday Heat Dome engulfed western Canada. As a result of this extreme heat event (EHE), emergency dispatchers received an unparalleled increase in incoming 911 calls for ambul…
View article: Biological sex‐related differences in the postprandial triglyceride response to intermittent hypoxaemia in young adults: a randomized crossover trial
Biological sex‐related differences in the postprandial triglyceride response to intermittent hypoxaemia in young adults: a randomized crossover trial Open
Obstructive sleep apnoea is characterized by chronic intermittent hypoxaemia and is independently associated with an increased risk of metabolic comorbidities (e.g. type II diabetes and ischaemic heart disease). These comorbidities could b…
View article: Media-Based Post-Event Impact Analysis of the 2021 Heat Dome in Canada
Media-Based Post-Event Impact Analysis of the 2021 Heat Dome in Canada Open
The unprecedented 2021 Heat Dome caused wide-ranging and long-lasting impacts in western Canada, including 619 confirmed heat-related deaths in British Columbia, a doubling of emergency medical calls, increased hospitalisations, infrastruc…
View article: Hot Topic: A Systematic Review and Content Analysis of Heat-Related Messages During the 2021 Heat Dome in Canada
Hot Topic: A Systematic Review and Content Analysis of Heat-Related Messages During the 2021 Heat Dome in Canada Open
Context: During the summer of 2021, western Canada experienced a deadly heat event. From the first heat alert to postevent reporting, thousands of media articles were published that reference the heat event. However, a gap remains in under…
View article: No impact of a high‐fat meal coupled with intermittent hypoxemia on acute kidney injury biomarkers in adults with and without obstructive sleep apnea
No impact of a high‐fat meal coupled with intermittent hypoxemia on acute kidney injury biomarkers in adults with and without obstructive sleep apnea Open
Obstructive sleep apnea (OSA) is characterized by chronic intermittent hypoxemia, which is associated with progressive loss of kidney function, where postprandial fluctuations in renal physiology may further compromise oxygen supply and ki…
View article: Working under the 2021 Heat Dome: A Content Analysis of Occupational Impacts Mentioned in the Canadian Media
Working under the 2021 Heat Dome: A Content Analysis of Occupational Impacts Mentioned in the Canadian Media Open
Extreme heat events directly impact worker health and cause additional cascading and transitional workplace impacts. However, current investigations on these impacts often rely on specific datasets (e.g., compensation claims, hospitalizati…
View article: The Intersection of the COVID-19 Pandemic and the 2021 Heat Dome in Canadian Digital News Media: A Content Analysis
The Intersection of the COVID-19 Pandemic and the 2021 Heat Dome in Canadian Digital News Media: A Content Analysis Open
During the 2021 Heat Dome, 619 people in British Columbia died due to the heat. This public health disaster was made worse by the ongoing COVID-19 pandemic. Few studies have explored the intersection of heat with COVID-19, and none in Cana…
View article: Elevations in serum brain-derived neurotrophic factor following occupational heat stress are not influenced by age or common chronic disease
Elevations in serum brain-derived neurotrophic factor following occupational heat stress are not influenced by age or common chronic disease Open
With global warming, workers are increasingly exposed to strenuous occupations in hot environments. Given age- and disease-associated declines in thermoregulatory function, older workers are at an elevated risk of developing heat-related i…