Nicholas Gravbrot
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View article: Corrigendum to “Differentiation of survival outcomes by anatomic involvement and histology with the revised 2023 International Federation of Gynecology and Obstetrics staging system for endometrial cancer” Eur. J. Cancer (201) (April) 2024, 113913
Corrigendum to “Differentiation of survival outcomes by anatomic involvement and histology with the revised 2023 International Federation of Gynecology and Obstetrics staging system for endometrial cancer” Eur. J. Cancer (201) (April) 2024, 113913 Open
View article: Gene Expression Patterns Associated with Survival in Glioblastoma
Gene Expression Patterns Associated with Survival in Glioblastoma Open
The aim of this study was to investigate gene expression alterations associated with overall survival (OS) in glioblastoma (GBM). Using the Nanostring nCounter platform, we identified four genes (COL1A2, IGFBP3, NGFR, and WIF1) that achiev…
View article: Differentiation of Survival Outcomes by Anatomic Involvement and Histology with the Revised 2023 International Federation of Gynecology and Obstetrics Staging System for Endometrial Cancer
Differentiation of Survival Outcomes by Anatomic Involvement and Histology with the Revised 2023 International Federation of Gynecology and Obstetrics Staging System for Endometrial Cancer Open
View article: Safety Profile of Infinity Deep Brain Stimulation Electrode Placement in a 1.5T Interventional MRI Suite: Consecutive Single-Institution Case Series
Safety Profile of Infinity Deep Brain Stimulation Electrode Placement in a 1.5T Interventional MRI Suite: Consecutive Single-Institution Case Series Open
"Asleep" deep brain stimulation using general anesthesia and intraoperative MR imaging guidance is considered "off-label" use by current FDA guidelines but is widely used in neurosurgical practice, and excellent safety has been demonstrate…
View article: Asleep Deep Brain Stimulation of the Nucleus Ventralis Intermedius for Essential Tremor Using Indirect Targeting and Interventional Magnetic Resonance Imaging: <scp>Single‐Institution</scp> Case Series
Asleep Deep Brain Stimulation of the Nucleus Ventralis Intermedius for Essential Tremor Using Indirect Targeting and Interventional Magnetic Resonance Imaging: <span>Single‐Institution</span> Case Series Open
Background Literature on asleep deep brain stimulation (DBS) of the ventralis intermedius (Vim) nucleus in essential tremor is relatively sparse. Furthermore, controversy exists as to whether indirect (“consensus” or “atlas‐based”) targeti…
View article: Advanced Imaging and Direct Targeting of the Motor Thalamus and Dentato-Rubro-Thalamic Tract for Tremor: A Systematic Review
Advanced Imaging and Direct Targeting of the Motor Thalamus and Dentato-Rubro-Thalamic Tract for Tremor: A Systematic Review Open
Direct targeting methods for stereotactic neurosurgery in the treatment of essential tremor have been the subject of active research over the past decade but have not yet been systematically reviewed. We present a clinically oriented topic…
View article: Safe Transition to Pembrolizumab following Ipilimumab-Induced Guillain-Barré Syndrome: A Case Report and Review of the Literature
Safe Transition to Pembrolizumab following Ipilimumab-Induced Guillain-Barré Syndrome: A Case Report and Review of the Literature Open
Background . Immune checkpoint inhibitors are novel therapies with indications for treating several solid cancers. They are associated with immune-related adverse events, which are generally well tolerated. Though rare, severe side effects…
View article: Therapeutic Monoclonal Antibodies Targeting Immune Checkpoints for the Treatment of Solid Tumors
Therapeutic Monoclonal Antibodies Targeting Immune Checkpoints for the Treatment of Solid Tumors Open
Recently, modulation of immune checkpoints has risen to prominence as a means to treat a number of solid malignancies, given the durable response seen in many patients and improved side effect profile compared to conventional chemotherapeu…
View article: Severe Drug-Induced Liver Injury from Combination Encorafenib/Binimetinib
Severe Drug-Induced Liver Injury from Combination Encorafenib/Binimetinib Open
Encorafenib/binimetinib is a new combination BRAF/MEK inhibitor used in the treatment of advanced or metastatic BRAFV600-mutant melanoma. Though generally tolerated well, mild to moderate aminotransferase elevations are common. However, si…
View article: Increased Expression of DNA Repair Gene RAD51 Associated with Shorter Overall Survival in Glioblastoma
Increased Expression of DNA Repair Gene RAD51 Associated with Shorter Overall Survival in Glioblastoma Open
View article: Resumption of Positive-Pressure Ventilation Devices for Obstructive Sleep Apnea following Transsphenoidal Surgery: An Institutional Experience of a Surgical Cohort
Resumption of Positive-Pressure Ventilation Devices for Obstructive Sleep Apnea following Transsphenoidal Surgery: An Institutional Experience of a Surgical Cohort Open
Objectives Transsphenoidal surgery creates a skull base defect that may cause postoperative cerebrospinal fluid (CSF) leakage or pneumocephalus. This study reviewed the institutional experience of a pituitary center in managing patients wh…
View article: RTHP-09. DYSREGULATION OF Wnt SIGNALING PATHWAY CORRELATES WITH TREATMENT OUTCOME IN GLIOBLASTOMA MULTIFORME
RTHP-09. DYSREGULATION OF Wnt SIGNALING PATHWAY CORRELATES WITH TREATMENT OUTCOME IN GLIOBLASTOMA MULTIFORME Open
Glioblastoma multiforme (GBM) is the most common and most aggressive primary brain cancer with a median life expectancy of 13–15 months after surgery and chemo-radiation treatment. GBM is hallmarked by a poor response to radiation therapy …