Nicholas H. Angello
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View article: Publisher Correction: Rapid automated iterative small-molecule synthesis
Publisher Correction: Rapid automated iterative small-molecule synthesis Open
View article: Delocalized, asynchronous, closed-loop discovery of organic laser emitters
Delocalized, asynchronous, closed-loop discovery of organic laser emitters Open
Contemporary materials discovery requires intricate sequences of synthesis, formulation, and characterization that often span multiple locations with specialized expertise or instrumentation. To accelerate these workflows, we present a clo…
View article: Delocalized, Asynchronous, Closed-Loop Discovery of Organic Laser Emitters
Delocalized, Asynchronous, Closed-Loop Discovery of Organic Laser Emitters Open
Datasets related to the paper "Delocalized, Asynchronous, Closed-Loop Discovery of Organic Laser Emitters". Structures of all building blocks (cap_building_blocks.csv, bridge_building_blocks.csv, core_building_blocks.csv) Seed dataset of O…
View article: Closed-Loop Transfer Enables AI to Yield Chemical Knowledge
Closed-Loop Transfer Enables AI to Yield Chemical Knowledge Open
AI-guided closed-loop experimentation has recently emerged as a promising method to optimize objective functions,1,2 but the substantial potential of this traditionally black-box approach to reveal new scientific knowledge has remained lar…
View article: Delocalized, Asynchronous, Closed-Loop Discovery of Organic Laser Emitters
Delocalized, Asynchronous, Closed-Loop Discovery of Organic Laser Emitters Open
Contemporary materials discovery requires intricate sequences of synthesis, formulation and characterization that often span multiple locations with specialized expertise or instrumentation. To accelerate these workflows, we present a clou…
View article: Delocalized, Asynchronous, Closed-Loop Discovery of Organic Laser Emitters
Delocalized, Asynchronous, Closed-Loop Discovery of Organic Laser Emitters Open
Datasets related to the paper "Delocalized, Asynchronous, Closed-Loop Discovery of Organic Laser Emitters". Structures of all building blocks (cap_building_blocks.csv, bridge_building_blocks.csv, core_building_blocks.csv) Seed dataset of O…
View article: Rapid Automated Iterative Small Molecule Synthesis
Rapid Automated Iterative Small Molecule Synthesis Open
Automated iterative small molecule synthesis has the potential to advance and democratize the discovery of new medicines, materials, and many other classes of functional chemical matter. But to date this approach has been limited by a requ…
View article: A Materials Acceleration Platform for Organic Laser Discovery (Adv. Mater. 6/2023)
A Materials Acceleration Platform for Organic Laser Discovery (Adv. Mater. 6/2023) Open
Accelerated Materials Discovery In article number 2207070, Tony C Wu, Alán Aspuru-Guzik, and co-workers report a materials acceleration platform to automatically search for high-performing organic laser molecules, which includes synthesis,…
View article: A Materials Acceleration Platform for Organic Laser Discovery
A Materials Acceleration Platform for Organic Laser Discovery Open
Conventional materials discovery is a laborious and time‐consuming process that can take decades from initial conception of the material to commercialization. Recent developments in materials acceleration platforms promise to accelerate ma…
View article: Closed-loop optimization of general conditions for heteroaryl Suzuki coupling
Closed-loop optimization of general conditions for heteroaryl Suzuki coupling Open
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View article: Closed-loop optimization of general conditions for heteroaryl Suzuki coupling
Closed-loop optimization of general conditions for heteroaryl Suzuki coupling Open
No description provided.
View article: Using automated synthesis to understand the role of side chains on molecular charge transport
Using automated synthesis to understand the role of side chains on molecular charge transport Open
View article: Machine Learning May Sometimes Simply Capture Literature Popularity Trends: A Case Study of Heterocyclic Suzuki–Miyaura Coupling
Machine Learning May Sometimes Simply Capture Literature Popularity Trends: A Case Study of Heterocyclic Suzuki–Miyaura Coupling Open
Applications of machine learning (ML) to synthetic chemistry rely on the assumption that large numbers of literature-reported examples should enable construction of accurate and predictive models of chemical reactivity. This paper demonstr…
View article: A Materials Acceleration Platform for Organic Laser Discovery
A Materials Acceleration Platform for Organic Laser Discovery Open
Conventional materials discovery is a laborious and time-consuming process that can take decades from initial conception of the material to commercialization. Recent developments in materials acceleration platforms promise to accelerate ma…
View article: Using Automated Synthesis to Understand the Role of Side Chains on Molecular Charge Transport
Using Automated Synthesis to Understand the Role of Side Chains on Molecular Charge Transport Open
The development of next-generation organic electronic materials critically relies on understanding structure-function relationships in conjugated polymers. However, unlocking the full potential of organic materials requires access to their…
View article: Using Automated Synthesis to Understand the Role of Side Chains on Molecular Charge Transport
Using Automated Synthesis to Understand the Role of Side Chains on Molecular Charge Transport Open
The development of next-generation organic electronic materials critically relies on understanding structure-function relationships in conjugated polymers. However, unlocking the full potential of organic materials requires access to their…
View article: Transition between Nonresonant and Resonant Charge Transport in Molecular Junctions
Transition between Nonresonant and Resonant Charge Transport in Molecular Junctions Open
Efficient long-range charge transport is required for high-performance molecular electronic devices. Resonant transport is thought to occur in single molecule junctions when molecular frontier orbital energy levels align with electrode Fer…
View article: Synthesis and Spectrophotometric Analysis of 1-Azafluorenone Derivatives
Synthesis and Spectrophotometric Analysis of 1-Azafluorenone Derivatives Open
A new extension for the ‘one pot’ construction of diverse 1-azafluorene derivatives featuring a Diels–Alder/retro-Diels–Alder cycloaddition is reported. Conditions were also determined for oxidation to the derived azafluorenones. The spect…
View article: Development Of A One Pot [4+2]/r[4+2] 2-Pyridone Synthesis And The Fluorescence Of 2-Pyridone Azafluorenones
Development Of A One Pot [4+2]/r[4+2] 2-Pyridone Synthesis And The Fluorescence Of 2-Pyridone Azafluorenones Open
We report the concise synthesis of several tricyclic 2-pyridones via a one pot sequence involving an aldol condensation, alkene isomerization, intramolecular Diels-Alder cycloaddition, and selective retro-Diels-Alder cycloreversion. The st…
View article: Domino Reaction Sequence for the Synthesis of [2.2.2]Diazabicycloalkenes and Base-Promoted Cycloreversion to 2-Pyridone Alkaloids
Domino Reaction Sequence for the Synthesis of [2.2.2]Diazabicycloalkenes and Base-Promoted Cycloreversion to 2-Pyridone Alkaloids Open
A new domino reaction sequence for the construction of 2-pyridone structures is reported. The reaction sequence begins with diacetyldiketopiperazine and proceeds via aldol condensation, alkene isomerization, and intramolecular Diels-Alder …