Nicholas J. Schaub
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View article: Assessing Efficiency in Artificial Neural Networks
Assessing Efficiency in Artificial Neural Networks Open
The purpose of this work was to develop an assessment technique and subsequent metrics that help in developing an understanding of the balance between network size and task performance in simple model networks. Here, exhaustive tests on si…
View article: OME-Zarr: a cloud-optimized bioimaging file format with international community support
OME-Zarr: a cloud-optimized bioimaging file format with international community support Open
View article: SEQUIN is an R/Shiny framework for rapid and reproducible analysis of RNA-seq data
SEQUIN is an R/Shiny framework for rapid and reproducible analysis of RNA-seq data Open
View article: OME-Zarr: a cloud-optimized bioimaging file format with international community support
OME-Zarr: a cloud-optimized bioimaging file format with international community support Open
A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across diverse mo…
View article: Cover Image
Cover Image Open
The cover image is based on the Research Article Measuring dimensionality of cellscaffold contacts of primary human bone marrow stromal cells culturedon electrospun fiber scaffolds by Stephanie J. Florczyk et al., https://doi.org/10.1002/j…
View article: Quantitative, traceable determination of cell viability using absorbance microscopy
Quantitative, traceable determination of cell viability using absorbance microscopy Open
Cell viability, an essential measurement for cell therapy products, lacks traceability. One of the most common cell viability tests is trypan blue dye exclusion where blue-stained cells are counted via brightfield imaging. Typically, live …
View article: Designing Trojan Detectors in Neural Networks Using Interactive Simulations
Designing Trojan Detectors in Neural Networks Using Interactive Simulations Open
This paper addresses the problem of designing trojan detectors in neural networks (NNs) using interactive simulations. Trojans in NNs are defined as triggers in inputs that cause misclassification of such inputs into a class (or classes) u…
View article: Scientific Calculator for Designing Trojan Detectors in Neural Networks
Scientific Calculator for Designing Trojan Detectors in Neural Networks Open
This work presents a web-based interactive neural network (NN) calculator and a NN inefficiency measurement that has been investigated for the purpose of detecting trojans embedded in NN models. This NN Calculator is designed on top of Ten…
View article: Assessing Intelligence in Artificial Neural Networks
Assessing Intelligence in Artificial Neural Networks Open
The purpose of this work was to develop of metrics to assess network architectures that balance neural network size and task performance. To this end, the concept of neural efficiency is introduced to measure neural layer utilization, and …
View article: Neural Network Calculator for Designing Trojan Detectors
Neural Network Calculator for Designing Trojan Detectors Open
This is software that has the purpose of a web-based interactive neural network (NN) calculator with a NN inefficiency measurement. The software has been developed for the purpose of detecting Trojans embedded in NN models.
View article: Comparison of Artificial Intelligence based approaches to cell function prediction
Comparison of Artificial Intelligence based approaches to cell function prediction Open
View article: A method to rapidly analyze the simultaneous release of multiple pharmaceuticals from electrospun fibers
A method to rapidly analyze the simultaneous release of multiple pharmaceuticals from electrospun fibers Open
View article: Differential expression of genes involved in the acute innate immune response to intracortical microelectrodes
Differential expression of genes involved in the acute innate immune response to intracortical microelectrodes Open
View article: Deep learning predicts function of live retinal pigment epithelium from quantitative microscopy
Deep learning predicts function of live retinal pigment epithelium from quantitative microscopy Open
Increases in the number of cell therapies in the preclinical and clinical phases have prompted the need for reliable and noninvasive assays to validate transplant function in clinical biomanufacturing. We developed a robust characterizatio…
View article: AMD Cell Therapy Efficacy Assessment Using Artificial Intelligence-Based Multi-Spectral Imaging
AMD Cell Therapy Efficacy Assessment Using Artificial Intelligence-Based Multi-Spectral Imaging Open
View article: Combining electrospun nanofibers with cell-encapsulating hydrogel fibers for neural tissue engineering
Combining electrospun nanofibers with cell-encapsulating hydrogel fibers for neural tissue engineering Open
A promising component of biomaterial constructs for neural tissue engineering are electrospun fibers, which differentiate stem cells and neurons as well as direct neurite growth. However, means of protecting neurons, glia, and stem cells s…
View article: Modeling, validation and verification of three-dimensional cell-scaffold contacts from terabyte-sized images
Modeling, validation and verification of three-dimensional cell-scaffold contacts from terabyte-sized images Open
View article: REShAPE – A Cloud-Computing Based Cell Morphometry Analyzer for Development of a Release Criteria of Clinical Grade Retinal Pigment Epithelium
REShAPE – A Cloud-Computing Based Cell Morphometry Analyzer for Development of a Release Criteria of Clinical Grade Retinal Pigment Epithelium Open
View article: Electrospun Fibers for Spinal Cord Injury Research and Regeneration
Electrospun Fibers for Spinal Cord Injury Research and Regeneration Open
Electrospinning is the process by which a scaffold containing micrometer and nanometer diameter fibers are drawn from a polymer solution or melt using a large voltage gradient between a polymer emitting source and a grounded collector. Ram…
View article: The Effect of Surface Modification of Aligned Poly-L-Lactic Acid Electrospun Fibers on Fiber Degradation and Neurite Extension
The Effect of Surface Modification of Aligned Poly-L-Lactic Acid Electrospun Fibers on Fiber Degradation and Neurite Extension Open
The surface of aligned, electrospun poly-L-lactic acid (PLLA) fibers was chemically modified to determine if surface chemistry and hydrophilicity could improve neurite extension from chick dorsal root ganglia. Specifically, diethylenetriam…
View article: Analysis of neurite outgrowth on electrospun fiber scaffolds in the presence of blebbistatin and paclitaxel
Analysis of neurite outgrowth on electrospun fiber scaffolds in the presence of blebbistatin and paclitaxel Open
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