Nicholas J. Terrill
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View article: Hierarchical biomechanical characterisation of riboflavin-UVA crosslinking and decorin treatment in the porcine cornea
Hierarchical biomechanical characterisation of riboflavin-UVA crosslinking and decorin treatment in the porcine cornea Open
Introduction The mechanisms underpinning the stiffening and stabilising effect of riboflavin/UVA crosslinking on the corneal stroma are not well understood. We report the findings of a biomechanics and synchrotron X-ray scattering study ai…
View article: In situ early-stage CO2 corrosion scale study with 2D synchrotron SAXS-WAXS
In situ early-stage CO2 corrosion scale study with 2D synchrotron SAXS-WAXS Open
View article: Variations in mineral prestrain, nanostructure, and microarchitecture play a role in intervertebral disc loading
Variations in mineral prestrain, nanostructure, and microarchitecture play a role in intervertebral disc loading Open
View article: Enterohaemorrhagic <i>Escherichia coli</i> AdhE spirosome length correlates with enzymatic directionality and is perturbed by salicylidene acylhydrazides
Enterohaemorrhagic <i>Escherichia coli</i> AdhE spirosome length correlates with enzymatic directionality and is perturbed by salicylidene acylhydrazides Open
Enterohaemorrhagic Escherichia coli causes sporadic, and sometimes large-scale, food poisoning outbreaks, for which antibiotic treatment in humans is contraindicated. As an alternative form of therapy, previous studies developed the family…
View article: Integrating ultrastructural diffraction imaging and multiscale modelling to unveil the nanoscale mechanics of arthropod cuticle in bending
Integrating ultrastructural diffraction imaging and multiscale modelling to unveil the nanoscale mechanics of arthropod cuticle in bending Open
Determining the mechano-structural relations in biological materials with hierarchical structure is crucial to understanding natural optimization strategies and designing functional bioinspired composites. However, measuring the nanoscale …
View article: 3D Nanowire Pt Catalysts with Enhanced Stability for the Oxygen Reduction Reaction
3D Nanowire Pt Catalysts with Enhanced Stability for the Oxygen Reduction Reaction Open
We report that self-supporting mesoporous platinum 3D nanowires with a single diamond (SD) morphology and a high specific surface area of 40.4 m2 g-1 demonstrated enhanced stability toward the oxygen reduction reactio…
View article: Ultrastructural Aspects of Corneal Functional Recovery in Rats Following Intrastromal Keratocyte Injection
Ultrastructural Aspects of Corneal Functional Recovery in Rats Following Intrastromal Keratocyte Injection Open
CSK injection resolved early stage corneal scarring by restoring stromal collagen arrangement and PG distribution, further endorsing its potential for treating corneal opacities.
View article: Wet spinning of sodium carboxymethyl cellulose–sodium caseinate hydrogel fibres: relationship between rheology and spinnability
Wet spinning of sodium carboxymethyl cellulose–sodium caseinate hydrogel fibres: relationship between rheology and spinnability Open
Mimicking the fibrous structures of meat is a significant challenge because natural plant protein assemblies lack the fibrous organisation ubiquitous in mammalian muscle tissues.
View article: Correction: Wet spinning of sodium carboxymethyl cellulose–sodium caseinate hydrogel fibres: relationship between rheology and spinnability
Correction: Wet spinning of sodium carboxymethyl cellulose–sodium caseinate hydrogel fibres: relationship between rheology and spinnability Open
Correction for ‘Wet spinning of sodium carboxymethyl cellulose–sodium caseinate hydrogel fibres: relationship between rheology and spinnability’ by Lathika Vaniyan et al. , Soft Matter , 2025, https://doi.org/10.1039/d4sm00705k.
View article: In Situ Early-Stage Co2 Corrosion Scale with 2d Synchrotron Saxs-Waxs
In Situ Early-Stage Co2 Corrosion Scale with 2d Synchrotron Saxs-Waxs Open
View article: Nonlinear Stress‐Induced Transformations in Collagen Fibrillar Organization, Disorder and Strain Mechanisms in the Bone‐Cartilage Unit
Nonlinear Stress‐Induced Transformations in Collagen Fibrillar Organization, Disorder and Strain Mechanisms in the Bone‐Cartilage Unit Open
By developing a 3D X‐ray modeling and spatially correlative imaging method for fibrous collagenous tissues, this study provides a comprehensive mapping of nanoscale deformation in the collagen fibril network across the intact bone‐cartilag…
View article: Synchrotron Tomography-Based Inversion Pipeline for Estimating Elastic Properties of Rat Vertebral Endplate Finite Element Models
Synchrotron Tomography-Based Inversion Pipeline for Estimating Elastic Properties of Rat Vertebral Endplate Finite Element Models Open
Lower back pain is linked to vertebral biomechanics, with vertebral endplates (VEPs) playing a key role. Finite element modelling (FEM) is a powerful tool for studying VEP biomechanics but relies on accurate material property inputs, which…
View article: Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading
Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading Open
The function of all musculoskeletal joints depends on hierarchical structures spanning the molecular to whole joint scales. Investigating biomechanics across length scales requires correlative multiscale experimental methods. This study ap…
View article: Nanostructural Evolution During Carious and Demineralisation Process of Human Dentine Using Small Angle X-Ray Scattering Tensor Tomography
Nanostructural Evolution During Carious and Demineralisation Process of Human Dentine Using Small Angle X-Ray Scattering Tensor Tomography Open
View article: Correction to “Continuous-Flow Laboratory SAXS for In Situ Determination of the Impact of Hydrophilic Block Length on Spherical Nano-Object Formation during Polymerization-Induced Self-Assembly”
Correction to “Continuous-Flow Laboratory SAXS for In Situ Determination of the Impact of Hydrophilic Block Length on Spherical Nano-Object Formation during Polymerization-Induced Self-Assembly” Open
[This corrects the article DOI: 10.1021/acs.macromol.3c00585.].
View article: Evaluation of cataract formation in fish exposed to environmental radiation at Chernobyl and Fukushima
Evaluation of cataract formation in fish exposed to environmental radiation at Chernobyl and Fukushima Open
View article: Continuous-Flow Laboratory SAXS for In Situ Determination of the Impact of Hydrophilic Block Length on Spherical Nano-Object Formation during Polymerization-Induced Self-Assembly
Continuous-Flow Laboratory SAXS for In Situ Determination of the Impact of Hydrophilic Block Length on Spherical Nano-Object Formation during Polymerization-Induced Self-Assembly Open
In situ small-angle X-ray scattering (SAXS) is a powerful technique for characterizing block-copolymer nano-object formation during polymerization-induced self-assembly. To work effectively in situ, it requires high intensity X-rays which …
View article: A Cross-Sectional Study of Bone Nanomechanics in Hip Fracture and Aging
A Cross-Sectional Study of Bone Nanomechanics in Hip Fracture and Aging Open
Bone mechanics is well understood at every length scale except the nano-level. We aimed to investigate the relationship between bone nanoscale and tissue-level mechanics experimentally. We tested two hypotheses: (1) nanoscale strains were …
View article: Ultra-low oxygen, liquid sample cell for <i>in situ</i> synchrotron-based small-wide angle scattering (SAXS-WAXS)
Ultra-low oxygen, liquid sample cell for <i>in situ</i> synchrotron-based small-wide angle scattering (SAXS-WAXS) Open
Here, we report the design and successful implementation of an ultra-low oxygen sample cell for use on the SAXS-WAXS (small-wide angle x-ray scattering) beamline I22 at DIAMOND. The rigorous exclusion of oxygen is found to require double j…
View article: Polymer and Soft Matter Research at Diamond Light Source
Polymer and Soft Matter Research at Diamond Light Source Open
Polymer and soft matter research have played an integral part in the development of Diamond Light Source ever since the facility took its first users in 2007. Early experiments explored highly swollen cubic lipid scaffolds [Citation1] usin…
View article: Exploring the Nanostructures Accessible to an Organic Surfactant Atmospheric Aerosol Proxy
Exploring the Nanostructures Accessible to an Organic Surfactant Atmospheric Aerosol Proxy Open
The composition of atmospheric aerosols varies with time, season, location, and environment. This affects key aerosol properties such as hygroscopicity and reactivity, influencing the aerosol's impact on the climate and air quality. The or…
View article: Collagen pre-strain discontinuity at the bone—Cartilage interface
Collagen pre-strain discontinuity at the bone—Cartilage interface Open
The bone-cartilage unit (BCU) is a universal feature in diarthrodial joints, which is mechanically-graded and subjected to shear and compressive strains. Changes in the BCU have been linked to osteoarthritis (OA) progression. Here we repor…
View article: Investigating the Fibrillar Ultrastructure and Mechanics in Keloid Scars Using In Situ Synchrotron X-ray Nanomechanical Imaging
Investigating the Fibrillar Ultrastructure and Mechanics in Keloid Scars Using In Situ Synchrotron X-ray Nanomechanical Imaging Open
Fibrotic scarring is prevalent in a range of collagenous tissue disorders. Understanding the role of matrix biophysics in contributing to fibrotic progression is important to develop therapies, as well as to elucidate biological mechanisms…
View article: Tropocollagen springs allow collagen fibrils to stretch elastically
Tropocollagen springs allow collagen fibrils to stretch elastically Open
View article: The evolution of surface structure during simulated atmospheric ageing of nano-scale coatings of an organic surfactant aerosol proxy
The evolution of surface structure during simulated atmospheric ageing of nano-scale coatings of an organic surfactant aerosol proxy Open
A nano-scale proxy for atmospheric surfactant organic films undergoes changes in morphology and hygroscopicity during simulated atmospheric processing.
View article: An organic crystalline state in ageing atmospheric aerosol proxies: spatially resolved structural changes in levitated fatty acid particles
An organic crystalline state in ageing atmospheric aerosol proxies: spatially resolved structural changes in levitated fatty acid particles Open
Organic aerosols are key components of the Earth's atmospheric system. The phase state of organic aerosols is known to be a significant factor in determining aerosol reactivity, water uptake and atmospheric lifetime – with wide implication…
View article: Collagen Pre-strain Discontinuity at the Cartilage - Bone Interface
Collagen Pre-strain Discontinuity at the Cartilage - Bone Interface Open
The bone-cartilage unit (BCU) is a universal feature in diarthrodial joints, which is mechanically-graded and subjected to shear and compressive strains. Changes in the BCU have been linked to osteoarthritis progression. Here we report exi…
View article: Reversible changes in the 3D collagen fibril architecture during cyclic loading of healthy and degraded cartilage
Reversible changes in the 3D collagen fibril architecture during cyclic loading of healthy and degraded cartilage Open
View article: Data supporting the study "An organic crystalline state in ageing atmospheric aerosol proxies: spatially resolved structural changes in levitated fatty acid particles" by Milsom et al. (2021))
Data supporting the study "An organic crystalline state in ageing atmospheric aerosol proxies: spatially resolved structural changes in levitated fatty acid particles" by Milsom et al. (2021)) Open
Data supporting the figures and findings presented in the study "An organic crystalline state in ageing atmospheric aerosol proxies: spatially resolved structural changes in levitated fatty acid particles" by Milsom et al. (2021), …
View article: Data supporting the study "An organic crystalline state in ageing atmospheric aerosol proxies: spatially resolved structural changes in levitated fatty acid particles" by Milsom et al. (2021))
Data supporting the study "An organic crystalline state in ageing atmospheric aerosol proxies: spatially resolved structural changes in levitated fatty acid particles" by Milsom et al. (2021)) Open
Data supporting the figures and findings presented in the study "An organic crystalline state in ageing atmospheric aerosol proxies: spatially resolved structural changes in levitated fatty acid particles" by Milsom et al. (2021), …