Nicholas M. A. Smith
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View article: Visual Scanning and Technique Improve Performance in a Standardized Soccer Passing Task
Visual Scanning and Technique Improve Performance in a Standardized Soccer Passing Task Open
Background/Objectives: Passing is the most frequent and impactful action in soccer. It requires players to control the ball and pass accurately with either foot, make quick decisions, and scan the field while under pressure. Using a recent…
View article: Scanning When Passing: A Reliable and Valid Standardized Soccer Test
Scanning When Passing: A Reliable and Valid Standardized Soccer Test Open
Background/Objectives: In soccer, scanning before receiving the ball helps players better perceive and interpret their surroundings, enabling faster and more effective passes. Despite its importance, no standardized tests currently incorpo…
View article: Dribbling and passing performances predict individual success in small-sided soccer games
Dribbling and passing performances predict individual success in small-sided soccer games Open
Our aim was to identify the underlying physical and technical skill traits associated with success in 3v3 small-sided soccer games. We quantified the sprinting, dribbling, and passing performances of 41 individual youth footballers from an…
View article: <i>BDNF-DT and BDNF-AS-DT</i>: Novel Genes in the <i>BDNF</i> locus
<i>BDNF-DT and BDNF-AS-DT</i>: Novel Genes in the <i>BDNF</i> locus Open
Divergent transcription from bidirectional promoters is frequently observed in eukaryotic genomes, but the biological relevance of divergent RNA transcripts (DT) is unknown. We identified and characterized BDNF-DT , a novel DT gene, and BD…
View article: Using Age- and Size-Corrected Measures of Technical Skill to Better Assess the Performances of Youth Soccer Players
Using Age- and Size-Corrected Measures of Technical Skill to Better Assess the Performances of Youth Soccer Players Open
Youth soccer academies are dominated by the older players in each annual age cohort because they are judged to be better at the time of selection. Failing to identify talented players because they are simply younger in their cohort is a pr…
View article: Influence of Age and Body Size on the Dribbling Performance of Young Elite Soccer Players: A Cross-Sectional Descriptive Study
Influence of Age and Body Size on the Dribbling Performance of Young Elite Soccer Players: A Cross-Sectional Descriptive Study Open
Background/Objectives: Dribbling is a fundamental skill in soccer, but assessing the performance of youth players in this skill is complicated by the confounded effects of age and physical development. In this study, our aim was to quantif…
View article: Sex-specific performance, trade-offs and trait repeatability across the lifetime of the world's largest semelparous mammal (<i>Dasyurus hallucatus</i>)
Sex-specific performance, trade-offs and trait repeatability across the lifetime of the world's largest semelparous mammal (<i>Dasyurus hallucatus</i>) Open
The activities that define survival and reproductive success in animals depend on their physical performance. However, performance is a complex trait, and organisms must balance competing demands of multiple underlying factors every time t…
View article: Different Genes are Recruited During Convergent Evolution of Pregnancy and the Placenta
Different Genes are Recruited During Convergent Evolution of Pregnancy and the Placenta Open
The repeated evolution of the same traits in distantly related groups (convergent evolution) raises a key question in evolutionary biology: do the same genes underpin convergent phenotypes? Here, we explore one such trait, viviparity (live…
View article: Onasemnogene abeparvovec in spinal muscular atrophy: an Australian experience of safety and efficacy
Onasemnogene abeparvovec in spinal muscular atrophy: an Australian experience of safety and efficacy Open
Objective To provide a greater understanding of the tolerability, safety and clinical outcomes of onasemnogene abeparvovec in real‐world practice, in a broad population of infants with spinal muscular atrophy (SMA). Methods A prospective c…
View article: Carborane clusters increase the potency of bis-substituted cyclam derivatives against<i>Mycobacterium tuberculosis</i>
Carborane clusters increase the potency of bis-substituted cyclam derivatives against<i>Mycobacterium tuberculosis</i> Open
Bis-substituted cyclam derivatives have recently emerged as a promising new class of antibacterial agents, displaying excellent activity against drug-resistant Mycobacterium tuberculosis ( Mtb ). Carborane pendants enhance this activity.
View article: Prospects in Connecting Genetic Variation to Variation in Fertility in Male Bees
Prospects in Connecting Genetic Variation to Variation in Fertility in Male Bees Open
Bees are economically and ecologically important pollinating species. Managed and native bee species face increasing pressures from human-created stressors such as habitat loss, pesticide use, and introduced pathogens. There has been incre…
View article: Genetic variation at RAB3GAP2 and its role in exercise-related adaptation and recovery
Genetic variation at RAB3GAP2 and its role in exercise-related adaptation and recovery Open
Skeletal muscle fiber composition and capillary density influence physical performance and whole-body metabolic properties. ~45% of the variance in fiber type is heritable, which motivated us to perform a genome-wide association study of s…
View article: Acknowledgements
Acknowledgements Open
View article: Unique DNA Methylation Profiles Are Associated with cis-Variation in Honey Bees
Unique DNA Methylation Profiles Are Associated with cis-Variation in Honey Bees Open
DNA methylation is an important epigenetic modification that mediates diverse processes such as cellular differentiation, phenotypic plasticity, and genomic imprinting. Mounting evidence suggests that local DNA sequence variation can be as…
View article: Genomic analysis of the genetic consequences of haplodiploidy in eusocial insects
Genomic analysis of the genetic consequences of haplodiploidy in eusocial insects Open
In this thesis I explore the reproductive biology of a subspecies of honey bee Apis mellifera capensis (hereafter, Capensis). Capensis is unusual among honey bees in that unmated workers can produce female offspring by thelytokous partheno…
View article: Predicting the defensive performance of individual players in one vs. one soccer games
Predicting the defensive performance of individual players in one vs. one soccer games Open
The aim of this study was to use technical skill and physical performance and coaches' rankings to predict the defensive performance of junior soccer players. Twenty-one male players (mean age 17.2 years, SD = 1.1) were recruited from the …
View article: Strikingly high levels of heterozygosity despite 20 years of inbreeding in a clonal honey bee
Strikingly high levels of heterozygosity despite 20 years of inbreeding in a clonal honey bee Open
Inbreeding (the mating between closely related individuals) often has detrimental effects that are associated with loss of heterozygosity at overdominant loci, and the expression of deleterious recessive alleles. However, determining which…
View article: Digest: Gene duplication and social evolution-Using big, open data to answer big, open questions
Digest: Gene duplication and social evolution-Using big, open data to answer big, open questions Open
View article: Cytogenetic basis of thelytoky in Apis mellifera capensis
Cytogenetic basis of thelytoky in Apis mellifera capensis Open