Nicholas Moellhoff
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View article: Quality indicators for breast reconstruction following cancer—an international Delphi consensus study supported by the European Society of Plastic, Reconstructive and Aesthetic Surgery
Quality indicators for breast reconstruction following cancer—an international Delphi consensus study supported by the European Society of Plastic, Reconstructive and Aesthetic Surgery Open
Background Quality indicators (QIs) are essential for assessing and improving healthcare delivery. Existing QIs for breast reconstruction are limited and do not comprehensively reflect clinical complexity or patient-centred outcomes. This …
View article: Cutting Risk, Not Just Skin—An International Survey on the Role of Preoperative Lab Values in Risk Stratification for Plastic and Reconstructive Surgery
Cutting Risk, Not Just Skin—An International Survey on the Role of Preoperative Lab Values in Risk Stratification for Plastic and Reconstructive Surgery Open
Background/Objectives: Plastic and reconstructive surgery (PRS) is characterized by its wide range of techniques and procedures, aiming to address the need for individualized treatment approaches. As PRS is predominantly performed in an el…
View article: Multi-Omics Molecular Profiling Enables Rapid Diagnosis of Erythrodermic Skin Diseases
Multi-Omics Molecular Profiling Enables Rapid Diagnosis of Erythrodermic Skin Diseases Open
Summary Erythroderma is an acute and potentially life-threatening inflammatory condition characterized by redness and scaling of > 90% of the skin. Its treatment is challenging because various underlying skin diseases can cause erythroderm…
View article: Platelet‐Rich Fibrin Mediates Beneficial Effects on Adipose‐Derived Stem Cells via Increased Levels of Key Cytokines
Platelet‐Rich Fibrin Mediates Beneficial Effects on Adipose‐Derived Stem Cells via Increased Levels of Key Cytokines Open
Recent studies showcased the regenerative potential of Platelet‐Rich Fibrin (PRF) combined with Adipose‐Derived Stem Cells (ASC). PRF enhances cellular proliferation through sustained growth factor secretion which are continuously released…
View article: Revealing the Perfect Smile: How Philtrum Length Shapes Lip Beauty
Revealing the Perfect Smile: How Philtrum Length Shapes Lip Beauty Open
Background Lips significantly influence facial aesthetics, driving the growing demand for lip augmentation procedures, particularly the bullhorn lip lift. As aesthetic medicine becomes more diverse with globalization, understanding how eth…
View article: Effect of Synchronized Radiofrequency and High-Intensity Facial Electrical Stimulation (HIFES) of the Upper Face
Effect of Synchronized Radiofrequency and High-Intensity Facial Electrical Stimulation (HIFES) of the Upper Face Open
Background Effects of upper facial aging can present as static forehead and periorbital rhytids as well as soft tissue volume loss. The latter can occur in conjunction with bony changes of the calvarial eyebrow and eyelid ptosis. Injection…
View article: Changes in the Microcirculation and Physiologic Perfusion Dynamics of Free DIEP Flaps in the First 72 h After Breast Reconstruction
Changes in the Microcirculation and Physiologic Perfusion Dynamics of Free DIEP Flaps in the First 72 h After Breast Reconstruction Open
Background/Objectives: The autologous reconstruction of the female breast using a microsurgical DIEP flap is a reliable and safe method. To detect impairments early and preserve the microvascular flap through timely revision, a better unde…
View article: Therapy for Dupuytren’s Disease (II): Collagenase Therapy vs. Limited Fasciectomy—A Long-Term Comparative Study
Therapy for Dupuytren’s Disease (II): Collagenase Therapy vs. Limited Fasciectomy—A Long-Term Comparative Study Open
Background: Dupuytren’s disease (DD) is a systemic connective tissue disorder of the palm, predominantly affecting men of Northern European or Caucasian origin over 55. In addition to conventional surgery, Dupuytren’s contracture can be tr…
View article: Bioactivated scaffolds promote angiogenesis and lymphangiogenesis for dermal regeneration in vivo
Bioactivated scaffolds promote angiogenesis and lymphangiogenesis for dermal regeneration in vivo Open
Chronic wounds represent an unresolved medical challenge with significant impact for patients’ quality of life and global healthcare. Diverse in origin, ischemic-hypoxic and inflammatory conditions play central roles as pathological featur…
View article: Impact of Postoperative Norepinephrine Administration on Free Flap Flow
Impact of Postoperative Norepinephrine Administration on Free Flap Flow Open
Background/Objectives: The perioperative interplay between blood pressure, vasopressors, and macrocirculation is well established. However, in the context of free flap surgery, the potential impact of these factors on microvascular flow re…
View article: What about the donor site morbidity – how invasive is the free latissimus dorsi flap?
What about the donor site morbidity – how invasive is the free latissimus dorsi flap? Open
Aims The free latissimus dorsi muscle (LDM) flap represents a workhorse procedure in the field of trauma and plastic surgery. However, only a small number of studies have examined this large group of patients with regard to the morbidity o…
View article: Clinical results of autologous fat transfer for basal thumb arthritis with a minimum of three years’ follow-up
Clinical results of autologous fat transfer for basal thumb arthritis with a minimum of three years’ follow-up Open
Aims In the treatment of basal thumb osteoarthritis (OA), intra-articular autologous fat transplantation has become of great interest within recent years as a minimally invasive and effective alternative to surgical intervention with regar…
View article: Therapy for Dupuytren’s Disease: Collagenase Therapy—A Long-Term Follow-Up Study
Therapy for Dupuytren’s Disease: Collagenase Therapy—A Long-Term Follow-Up Study Open
Background: Dupuytren’s disease (DD) is a systemic connective tissue disorder of the palm. It particularly affects men of Northern European or Caucasian origin over the age of 55. In addition to the classical surgical therapy via limited f…
View article: In Vivo Biocompatibility of Synechococcus sp. PCC 7002-Integrated Scaffolds for Skin Regeneration
In Vivo Biocompatibility of Synechococcus sp. PCC 7002-Integrated Scaffolds for Skin Regeneration Open
Cyanobacteria, commonly known as blue-green algae, are prevalent in freshwater systems and have gained interest for their potential in medical applications, particularly in skin regeneration. Among these, Synechococcus sp. strain PCC 7002 …
View article: Impact of Negative Pressure Wound Therapy on Perfusion Dynamics in Free Latissimus Dorsi Muscle Flaps
Impact of Negative Pressure Wound Therapy on Perfusion Dynamics in Free Latissimus Dorsi Muscle Flaps Open
Background: Free muscle flaps can develop significant postoperative edema and wound exudation, thereby increasing interstitial pressure and potentially compromising microcirculation. While concerns exist regarding negative pressure wound t…
View article: Biocompatibility of Synechococcus sp. PCC 7002 with Human Dermal Cells In Vitro
Biocompatibility of Synechococcus sp. PCC 7002 with Human Dermal Cells In Vitro Open
Being the green gold of the future, cyanobacteria have recently attracted considerable interest worldwide. This study investigates the adaptability and biocompatibility of the cyanobacterial strain Synechococcus sp. PCC 7002 with human der…
View article: Increasing Precision When Targeting the Depressor Anguli Oris Muscle With Neuromodulators: An Ultrasound-Based Investigation
Increasing Precision When Targeting the Depressor Anguli Oris Muscle With Neuromodulators: An Ultrasound-Based Investigation Open
Background Neuromodulator treatments of the perioral region are increasingly popular and aim to modulate the position of the modiolus. The predominantly targeted muscle is the depressor anguli oris (DAO) which allows for the modiolus to re…
View article: Radiofrequency and pulsed electromagnetic field application following liposuction—Clinical evaluation of performance and safety
Radiofrequency and pulsed electromagnetic field application following liposuction—Clinical evaluation of performance and safety Open
Objective With more than 1.5 million performed procedures, liposuction was the second most performed esthetic surgical procedure all over the world in males and in females in the year 2020. The objective of this open‐label, evaluator‐blind…
View article: The use of commercial fibrin glue in dermal replacement material reduces angiogenic and lymphangiogenic gene and protein expression in vitro
The use of commercial fibrin glue in dermal replacement material reduces angiogenic and lymphangiogenic gene and protein expression in vitro Open
Background Commercial fibrin glue is increasingly finding its way into clinical practice in surgeries to seal anastomosis, and initiate hemostasis or tissue repair. Human biological glue is also being discussed as a possible cell carrier. …
View article: Commentary on: The Dorsal Nasal Complex in Asians: Anatomical Variations and Injection Guide for Botulinum Toxin Type A
Commentary on: The Dorsal Nasal Complex in Asians: Anatomical Variations and Injection Guide for Botulinum Toxin Type A Open
Journal Article Commentary on: The Dorsal Nasal Complex in Asians: Anatomical Variations and Injection Guide for Botulinum Toxin Type A Get access Sebastian Cotofana, MD, PhD, Sebastian Cotofana, MD, PhD Corresponding Author: Dr Sebastian …
View article: Adipose-Derived Stem Cells Improve Angiogenesis and Lymphangiogenesis in a Hypoxic Dermal Regeneration Model In Vitro
Adipose-Derived Stem Cells Improve Angiogenesis and Lymphangiogenesis in a Hypoxic Dermal Regeneration Model In Vitro Open
Background and Objectives: Impaired wound healing represents an unsolved medical issue with a high impact on patients’ quality of life and global health care. Even though hypoxia is a significant limiting factor for wound healing, it revea…
View article: Clinical validation of the upper face first principle—A clinical, prospective, interventional <scp>split‐face</scp> study
Clinical validation of the upper face first principle—A clinical, prospective, interventional <span>split‐face</span> study Open
Background Previous clinical and anatomic investigations have identified the clinical relevance of facial biomechanics. Based on this new understanding, principles for facial aesthetic procedures were established: Lateral Face First, Deep …
View article: Analysis of Factors Determining Patient Survival after Receiving Free-Flap Reconstruction at a Single Center—A Retrospective Cohort Study
Analysis of Factors Determining Patient Survival after Receiving Free-Flap Reconstruction at a Single Center—A Retrospective Cohort Study Open
Background: Microsurgical tissue transfer revolutionized reconstructive surgery after extensive trauma, oncological resections, and severe infections. Complex soft tissue reconstructions are increasingly performed in multimorbid and elderl…
View article: ESPRAS Survey on Continuing Education in Plastic, Reconstructive and Aesthetic Surgery in Europe
ESPRAS Survey on Continuing Education in Plastic, Reconstructive and Aesthetic Surgery in Europe Open
Background Specialty training in plastic, reconstructive and aesthetic surgery is a prerequisite for safe and effective provision of care. The aim of this study was to assess and portray similarities and differences in the continuing educa…
View article: A prospective multicenter clinical trial evaluating the efficacy and safety of a hyaluronic acid‐based filler with <scp>Tri‐Hyal</scp> technology in the treatment of lips and the perioral area
A prospective multicenter clinical trial evaluating the efficacy and safety of a hyaluronic acid‐based filler with <span>Tri‐Hyal</span> technology in the treatment of lips and the perioral area Open
Background Age‐related changes of facial soft tissue cause clinical signs of facial aging such as lip atrophy, marionette lines, and an accentuated nasolabial fold. These changes can be modified using dermal fillers. Aims To evaluate effic…
View article: Visualization of the location and level of pain in common wrist pathologies using color-coded heatmaps
Visualization of the location and level of pain in common wrist pathologies using color-coded heatmaps Open
Background Pain of the hand and wrist affects a large patient population. If the onset is unrelated to recent trauma, the first medical contact is rarely established with a specialized hand surgeon. Objective The objective of this investig…