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View article: Toward widespread use of virtual trials in medical imaging innovation and regulatory science
Toward widespread use of virtual trials in medical imaging innovation and regulatory science Open
The rapid advancement in the field of medical imaging presents a challenge in keeping up to date with the necessary objective evaluations and optimizations for safe and effective use in clinical settings. These evaluations are traditionall…
View article: Optimization of array encoding for ultrasound imaging
Optimization of array encoding for ultrasound imaging Open
Objective . The transmit encoding model for synthetic aperture imaging is a robust and flexible framework for understanding the effects of acoustic transmission on ultrasound image reconstruction. Our objective is to use machine learning (…
View article: Bubble‐Based Microrobots with Rapid Circular Motions for Epithelial Pinning and Drug Delivery
Bubble‐Based Microrobots with Rapid Circular Motions for Epithelial Pinning and Drug Delivery Open
Remotely powered microrobots are proposed as next‐generation vehicles for drug delivery. However, most microrobots swim with linear trajectories and lack the capacity to robustly adhere to soft tissues. This limits their ability to navigat…
View article: Implementation of Constrained Swept Synthetic Aperture Using a Mechanical Fixture
Implementation of Constrained Swept Synthetic Aperture Using a Mechanical Fixture Open
Resolution and target detectability in ultrasound imaging are directly tied to the size of the imaging array. This is particularly important for imaging at depth, such as in the detection and diagnosis of hepatocellular carcinoma and other…
View article: Correction: Martinez et al. Cavitation Characterization of Size-Isolated Microbubbles in a Vessel Phantom Using Focused Ultrasound. Pharmaceutics 2022, 14, 1925
Correction: Martinez et al. Cavitation Characterization of Size-Isolated Microbubbles in a Vessel Phantom Using Focused Ultrasound. Pharmaceutics 2022, 14, 1925 Open
In the original publication [...]
View article: Cavitation Characterization of Size-Isolated Microbubbles in a Vessel Phantom Using Focused Ultrasound
Cavitation Characterization of Size-Isolated Microbubbles in a Vessel Phantom Using Focused Ultrasound Open
Pharmaceutical delivery can be noninvasively targeted on-demand by microbubble (MB) assisted focused ultrasound (FUS). Passive cavitation detection (PCD) has become a useful method to obtain real-time feedback on MB activity due to a FUS p…
View article: Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging
Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging Open
A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro-vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneou…
View article: Ultrasound Lesion Detectability as a Distance Between Probability Measures
Ultrasound Lesion Detectability as a Distance Between Probability Measures Open
Lesion detectability (LD) quantifies how easily a lesion or target can be distinguished from the background. LD is commonly used to assess the performance of new ultrasound imaging methods. The contrast-to-noise ratio (CNR) is the most pop…
View article: Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging
Enhanced visibility through microbubble-induced photoacoustic fluctuation imaging Open
A photoacoustic contrast mechanism is presented based on the photoacoustic fluctuations induced by microbubbles flowing inside a micro vessel filled with a continuous absorber. It is demonstrated that the standard deviation of a homogeneou…
View article: Frequency-Dependent Spatial Coherence in Conventional and Chirp Transmissions
Frequency-Dependent Spatial Coherence in Conventional and Chirp Transmissions Open
The development of adaptive imaging techniques is contingent on the accurate and repeatable characterization of ultrasonic image quality. Adaptive transmit frequency selection, filtering, and frequency compounding all offer the ability to …
View article: An Automated <scp>ALARA</scp> Method for Ultrasound
An Automated <span>ALARA</span> Method for Ultrasound Open
Objectives Ultrasound users are advised to observe the ALARA (as low as reasonably achievable) principle, but studies have shown that most do not monitor acoustic output metrics. We developed an adaptive ultrasound method that could sugges…
View article: Histogram Matching for Visual Ultrasound Image Comparison
Histogram Matching for Visual Ultrasound Image Comparison Open
The widespread development of new ultrasound image formation techniques has created a need for a standardized methodology for comparing the resulting images. Traditional methods of evaluation use quantitative metrics to assess the imaging …
View article: Resolution and Speckle Reduction in Cardiac Imaging
Resolution and Speckle Reduction in Cardiac Imaging Open
Cardiac imaging depends on clear visualization of several different structural and functional components to determine left ventricular and overall cardiac health. Ultrasound imaging is confounded by the characteristic speckle texture resul…
View article: Development of a novel intravascular oxygenator catheter: Oxygen mass transfer properties across nonporous hollow fiber membranes
Development of a novel intravascular oxygenator catheter: Oxygen mass transfer properties across nonporous hollow fiber membranes Open
Despite hypoxic respiratory failure representing a large portion of total hospitalizations and healthcare spending worldwide, therapeutic options beyond mechanical ventilation are limited. We demonstrate the technical feasibility of provid…
View article: Coherence-based quantification of acoustic clutter sources in medical ultrasound
Coherence-based quantification of acoustic clutter sources in medical ultrasound Open
The magnitudes by which aberration and incoherent noise sources, such as diffuse reverberation and thermal noise, contribute to degradations in image quality in medical ultrasound are not well understood. Theory predicting degradations in …
View article: Virtual clinical trials in medical imaging: a review
Virtual clinical trials in medical imaging: a review Open
The accelerating complexity and variety of medical imaging devices and methods have outpaced the ability to evaluate and optimize their design and clinical use. This is a significant and increasing challenge for both scientific investigati…
View article: Incoherent Clutter Suppression Using Lag-One Coherence
Incoherent Clutter Suppression Using Lag-One Coherence Open
The lag-one coherence (LOC), derived from the correlation between the nearest-neighbor channel signals, provides a reliable measure of clutter which, under certain assumptions, can be directly related to the signal-to-noise ratio of indivi…
View article: Synthetic Aperture Focusing for Multi-Covariate Imaging of Sub-Resolution Targets
Synthetic Aperture Focusing for Multi-Covariate Imaging of Sub-Resolution Targets Open
Coherence-based imaging methods suffer from reduced image quality outside the depth of field for focused ultrasound transmissions. Synthetic aperture methods can extend the depth of field by coherently compounding time-delayed echo data fr…
View article: Extending Retrospective Encoding for Robust Recovery of the Multistatic Data Set
Extending Retrospective Encoding for Robust Recovery of the Multistatic Data Set Open
Robust recovery of multistatic synthetic aperture data from conventional ultrasound sequences can enable complete transmit-and-receive focusing at all points in the field of view without the drawbacks of virtual-source synthetic aperture a…
View article: The Impact of Acoustic Clutter on Large Array Abdominal Imaging
The Impact of Acoustic Clutter on Large Array Abdominal Imaging Open
Abdominal imaging suffers from a particularly difficult acoustic environment-targets are located deep and overlying tissue layers with varying properties generate acoustic clutter. Increasing array size can overcome the penetration and lat…
View article: nbottenus/REFoCUS: Extending Retrospective Encoding for Robust Recovery of the Multistatic Dataset
nbottenus/REFoCUS: Extending Retrospective Encoding for Robust Recovery of the Multistatic Dataset Open
This release is intended for use with the paper "Extending Retrospective Encoding for Robust Recovery of the Multistatic Dataset"
View article: Measuring elastic nonlinearity in a soft solid using a tilted acoustic radiation force for shear wave excitation
Measuring elastic nonlinearity in a soft solid using a tilted acoustic radiation force for shear wave excitation Open
Excitation of multiple wave modes using shear wave elastography can result in additional information about the tissue's material characteristics and, potentially, improve disease diagnosis. Theoretically, tilting the acoustic radiation for…
View article: UltraDuke Version 1
UltraDuke Version 1 Open
DukeUltrasound is an ultrasound dataset collected at Duke University with a Verasonics c52v probe. It contains delay-and-sum (DAS) beamformed data as well as data post-processed with Siemens Dynamic TCE for speckle reduction, contrast enha…
View article: Lag-One Coherence as a Metric for Ultrasonic Image Quality
Lag-One Coherence as a Metric for Ultrasonic Image Quality Open
Reliable assessment of image quality is an important but challenging task in complex imaging environments such as those encountered in vivo. To address this challenge, we propose a novel imaging metric, known as the lag-one coherence (LOC)…
View article: Comparison of virtual source synthetic aperture beamforming with an element-based model
Comparison of virtual source synthetic aperture beamforming with an element-based model Open
Ultrasound beamforming relies on models of propagation to convert samples of the backscattered field through time into spatial image samples. The most common model is straight-line propagation of a focused wave, assuming a narrow steered a…