Nick J. Carroll
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View article: Isolation of nucleic acids using liquid–liquid phase separation of pH-sensitive elastin-like polypeptides
Isolation of nucleic acids using liquid–liquid phase separation of pH-sensitive elastin-like polypeptides Open
Extraction of nucleic acids (NAs) is critical for many methods in molecular biology and bioanalytical chemistry. NA extraction has been extensively studied and optimized for a wide range of applications and its importance to society has si…
View article: Microparticles with hierarchical porosity
Microparticles with hierarchical porosity Open
The present disclosure provides oxide microparticles with engineered hierarchical porosity and methods of manufacturing the same. Also described are structures that are formed by templating, impregnating, and/or precipitating the oxide mic…
View article: Centrifugal Generation of Droplet-Based 3D Cell Cultures
Centrifugal Generation of Droplet-Based 3D Cell Cultures Open
Quickly and easily producing uniform populations of microsphere-based 3D cell cultures using droplet-based templating methods has the potential to enable widespread use of such platforms in drug discovery or cancer research. Here, we advan…
View article: Dietary Modulation of Oxidative Stress in Alzheimer’s Disease
Dietary Modulation of Oxidative Stress in Alzheimer’s Disease Open
Cells generate unpaired electrons, typically via oxygen- or nitrogen-based by-products during normal cellular respiration and under stressed situations. These pro-oxidant molecules are highly unstable and may oxidize surrounding cellular m…
View article: Creating cellular patterns using genetically engineered, gold- and cell-binding polypeptides
Creating cellular patterns using genetically engineered, gold- and cell-binding polypeptides Open
Patterning cells on material surfaces is an important tool for the study of fundamental cell biology, tissue engineering, and cell-based bioassays. Here, the authors report a simple approach to pattern cells on gold patterned silicon subst…