Niclas Flosdorf YOU? Author Swipe

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Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche Open

Niclas Flosdorf, Janik Böhnke, Marcelo A. S. Toledo, Niklas Lutterbach, Vanesa Gómez Lerma , et al. · 2024

Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms Open

Margherita Vieri, Vithurithra Tharmapalan, Milena Kalmer, Julian Baumeister, Miloš Nikolić , et al. · 2023

Myeloproliferative neoplasms (MPNs) are caused by somatic driver mutations, such as JAK2 V617F , which might also affect cellular aging and senescence. Here, we analyzed the heterogeneity of aging in MPN patients and if this can be used to…

Supplementary Figures 1-5 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Supplementary Figure S1. Detailed view of LINC00920 exon 2 based on the GENCODE annotation. Supplementary Figure S2. LINC00920 knockdown increases the doubling time of VCaP cells. Supplementary Figure S3. LINC00920 does not affect ERG expr…

Supplementary Table S3 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Small interfering RNAs (siRNAs) used in this study.

Supplementary Table S6 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Proteins interacting with LINC00920 as identified by ChIRP-MS.

Supplementary Table S6 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Proteins interacting with LINC00920 as identified by ChIRP-MS.

Supplementary Table S4 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Sequences of biotinylated antisense ssDNA 20-mers used in chromatin isolation by RNA precipitation (ChIRP).

Supplementary Figures 1-5 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Supplementary Figure S1. Detailed view of LINC00920 exon 2 based on the GENCODE annotation. Supplementary Figure S2. LINC00920 knockdown increases the doubling time of VCaP cells. Supplementary Figure S3. LINC00920 does not affect ERG expr…

Supplementary Table S2 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Degenerate and gene-specific primer (GSP) oligos used for 5'- and 3'- rapid amplification of cDNA ends (RACE).

Data from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Numerous noncoding transcripts have been reported to correlate with cancer development and progression. Nevertheless, there remains a paucity of long noncoding RNAs (lncRNA) with well-elucidated functional roles. Here, we leverage the Inte…

Supplementary Table S5 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

LINC00920-deregulated genes (n=315) analyzed with Ingenuity Pathway Analysis (IPA).

Supplementary Table S1 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Quantitative PCR primer oligos used in this study.

Supplementary Table S1 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Quantitative PCR primer oligos used in this study.

Supplementary Table S5 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

LINC00920-deregulated genes (n=315) analyzed with Ingenuity Pathway Analysis (IPA).

Data from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Numerous noncoding transcripts have been reported to correlate with cancer development and progression. Nevertheless, there remains a paucity of long noncoding RNAs (lncRNA) with well-elucidated functional roles. Here, we leverage the Inte…

Supplementary Table S2 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Degenerate and gene-specific primer (GSP) oligos used for 5'- and 3'- rapid amplification of cDNA ends (RACE).

Supplementary Table S4 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Sequences of biotinylated antisense ssDNA 20-mers used in chromatin isolation by RNA precipitation (ChIRP).

Supplementary Table S3 from The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2023

Small interfering RNAs (siRNAs) used in this study.

Contents: Eur. J. Immunol. 12'22 Open

Lorenz Kretschmer, Tal Pecht, Katja Knapp, Sabrina B. Bennstein, Niclas Flosdorf , et al. · 2022

Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells Open

Niclas Flosdorf, Martin Zenke · 2022

Novel and exciting avenues allow generating dendritic cells (DC) by reprogramming of somatic cells. DC are obtained from induced pluripotent stem cells (iPS cells), referred to as ipDC, and by direct reprogramming of cells toward DC, refer…

Human DC3 Antigen Presenting Dendritic Cells From Induced Pluripotent Stem Cells Open

Taiki Satoh, Marcelo A. S. Toledo, Janik Boehnke, Kathrin Olschok, Niclas Flosdorf , et al. · 2021

Graphical Abstract Patient-specific iPS cells with JAK2 V617F mutation differentiate into DC3 dendritic cells, megakaryocytes and red blood cells.

Human DC3 Antigen Presenting Dendritic Cells from Induced Pluripotent Stem Cells Open

Taiki Satoh, Marcelo A. S. Toledo, Janik Boehnke, Kathrin Olschok, Niclas Flosdorf , et al. · 2021

Dendritic cells (DC) are professional antigen-presenting cells that develop from hematopoietic stem cells. Different DC subsets exist based on ontogeny, location and function, including the recently identified proinflammatory DC3 subset. D…

The ERG-Regulated <i>LINC00920</i> Promotes Prostate Cancer Cell Survival via the 14-3-3ϵ–FOXO Pathway Open

Arlou Kristina Angeles, Doreen Heckmann, Niclas Flosdorf, Stefan Duensing, Holger Sültmann · 2020

Numerous noncoding transcripts have been reported to correlate with cancer development and progression. Nevertheless, there remains a paucity of long noncoding RNAs (lncRNA) with well-elucidated functional roles. Here, we leverage the Inte…

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