Explanipedia

Copper doped hydroxyapatite nanocomposite thin films: synthesis, physico–chemical and biological evaluation Open

Carmen Steluţa Ciobanu, Daniela Predoi, Simona Liliana Iconaru, Mihai Valentin Predoi, Liliana Ghegoiu , et al. · 2024

Physico-Chemical and Biological Features of Fluorine-Substituted Hydroxyapatite Suspensions Open

Carmen Steluţa Ciobanu, Daniela Predoi, Simona Liliana Iconaru, Mihai Valentin Predoi, Krzysztof Rokosz , et al. · 2024

Infections related to orthopedic/stomatology surgery are widely recognized as a significant health concern. Therefore, the development of new materials with superior biological properties and good stability could represent a valuable alter…

Complex Evaluation of Nanocomposite-Based Hydroxyapatite for Biomedical Applications Open

Daniela Predoi, Simona Liliana Iconaru, Carmen Steluţa Ciobanu, Nicolas Buton, Mihai Valentin Predoi · 2023

A magnesium-doped hydroxyapatite in chitosan matrix (MgHApC) sample was developed as a potential platform for numerous applications in the pharmaceutical, medical, and food industries. Magnesium-doped hydroxyapatite suspensions in the chit…

Datasets and models for EnzBert Open

Nicolas Buton · 2023

Datasets and models for the paper: Predicting enzymatic function of protein sequences with attention

Datasets and models for EnzBert Open

Nicolas Buton · 2023

Datasets and models for the paper: Predicting enzymatic function of protein sequences with attention

Transformers models for interpretable and multilevel prediction of protein functions from sequences Open

Nicolas Buton · 2023

Automatic annotation of protein sequences is on the rise to manage the increasing number of experimentally unannotated sequences. First, we investigated the application of the Transformer for enzymatic function prediction. The EnzBert mode…

Predicting enzymatic function of protein sequences with attention Open

Nicolas Buton, F Coste, Yann Le Cunff · 2023

Motivation There is a growing number of available protein sequences, but only a limited amount has been manually annotated. For example, only 0.25% of all entries of UniProtKB are reviewed by human annotators. Further developing automatic …

Dextran-Coated Iron Oxide Nanoparticles Loaded with 5-Fluorouracil for Drug-Delivery Applications Open

Daniela Predoi, Mihaela Balaș, Mădălina Andreea Badea, Carmen Steluţa Ciobanu, Nicolas Buton , et al. · 2023

This study aims to design and test different formulations composed of dextran-coated iron oxide nanoparticles (IONPs) loaded with 5-Fluorouracil (5-FU) with varying nanoparticle:drug ratios on colorectal cancer cells. The stable suspension…

Response of the Endogenous Antioxidant Defense System Induced in RAW 264.7 Macrophages upon Exposure to Dextran-Coated Iron Oxide Nanoparticles Open

Mihaela Balaș, Simona Liliana Iconaru, Anca Dinischiotu, Nicolas Buton, Daniela Predoi · 2023

Presently, iron oxide nanoparticles are the only ones approved for clinical use as contrast agents in magnetic resonance imaging (MRI). Even though there is a high demand for these types of nanoparticles both for clinical use as well as fo…

Development of Novel Tetracycline and Ciprofloxacin Loaded Silver Doped Hydroxyapatite Suspensions for Biomedical Applications Open

Daniela Predoi, Simona Liliana Iconaru, Mihai‐Valentin Predoi, Nicolas Buton · 2022

The objective of this study consisted of the development of new materials with antimicrobial properties at the nanometric scale that could lead to an increase in therapeutic efficacy and reduction of toxic side effects. This work focuses o…

Datasets and models for EnzBert Open

Nicolas Buton · 2022

Datasets and models for the paper: Predicting enzymatic function of protein sequences with attention

EnzBert: Deep attention network for enzyme class predictions Open

Nicolas Buton, Yann Le Cunff, F Coste · 2022

Physicochemical Characterization of Europium-Doped Hydroxyapatite Thin Films with Antifungal Activity Open

Carmen Steluţa Ciobanu, Mihai Valentin Predoi, Nicolas Buton, Christelle Megier, Simona Liliana Iconaru , et al. · 2022

Owing to its unique biological and physicochemical properties, hydroxyapatite (HAp) represents one of the most extensively studied biomaterials for biomedical applications. It is well known that Candida is currently one of the fungi freque…

Development of Iron-Doped Hydroxyapatite Coatings Open

Daniela Predoi, Simona Liliana Iconaru, Carmen Steluţa Ciobanu, Silviu-Adrian Predoi, Nicolas Buton , et al. · 2021

It is known that iron is found as a trace element in bone tissue, the main inorganic constituent of which is hydroxyapatite. Therefore, iron-doped hydroxyapatite (HApFe) materials could be new alternatives for many biomedical applications.…

Rapport de stage Master 2 : Apprentissage et étude de Transformer pour la classification en familles protéiques Open

Nicolas Buton · 2020

Obtaining and Characterizing Thin Layers of Magnesium Doped Hydroxyapatite by Dip Coating Procedure Open

Daniela Predoi, Simona Liliana Iconaru, Mihai Valentin Predoi, Mikael Motelica‐Heino, Nicolas Buton , et al. · 2020

A simple dip coating procedure was used to prepare the magnesium doped hydroxyapatite coatings. An adapted co-precipitation method was used in order to obtain a Ca25−xMgx(PO4)6(OH)2, 25MgHAp (xMg = 0.25) suspension for preparing the coatin…

Dextran-Thyme Magnesium-Doped Hydroxyapatite Composite Antimicrobial Coatings Open

Simona Liliana Iconaru, Mihai Valentin Predoi, Mikael Motelica‐Heino, Daniela Predoi, Nicolas Buton , et al. · 2020

The dextran-thyme magnesium-doped hydroxyapatite (10MgHAp-Dex-thyme) composite layers were prepared by a dip-coating procedure from stable suspensions and further analyzed for the first time. Different characterization techniques were empl…

Biocompatible Layers Obtained from Functionalized Iron Oxide Nanoparticles in Suspension Open

Daniela Predoi, Simona Liliana Iconaru, Mihai Valentin Predoi, Nicolas Buton, Christelle Megier , et al. · 2019

Iron oxide nanoparticles have been extensively studied for challenges in applicable areas such as medicine, pharmacy, and the environment. The functionalization of iron oxide nanoparticles with dextran opens new prospects for application. …

Synthesis, Characterization, and Antimicrobial Activity of Magnesium-Doped Hydroxyapatite Suspensions Open

Daniela Predoi, Simona Liliana Iconaru, Mihai Valentin Predoi, George E. Stan, Nicolas Buton · 2019

Obtaining nanoscale materials has allowed for the miniaturization of components, which has led to the possibility of achieving more efficient devices with faster functions and much lower costs. While hydroxyapatite [HAp, Ca10(PO4)6(OH)2] i…

Evaluation of Antibacterial Activity of Zinc-Doped Hydroxyapatite Colloids and Dispersion Stability Using Ultrasounds Open

Daniela Predoi, Simona Liliana Iconaru, Mihai Valentin Predoi, Mikael Motelica‐Heino, Régis Guégan , et al. · 2019

This study proves that the new developed zinc-doped hydroxyapatite (ZnHAp) colloids by an adapted sol-gel method can be widely used in the pharmaceutical, medical, and environmental industries. ZnHAp nanoparticles were stabilized in an aqu…

Zinc Doped Hydroxyapatite Thin Films Prepared by Sol–Gel Spin Coating Procedure Open

Daniela Predoi, Simona Liliana Iconaru, Mihai Valentin Predoi, Nicolas Buton, Mikael Motelica‐Heino · 2019

In this study, ZnHAp layers deposited on a Si substrate were obtained by a sol–gel spin-coating procedure. The ZnHAp solutions used to obtain the ZnHAp coatings were investigated by dynamic light scattering (DLS) analysis, ζ-potential, ult…

Antimicrobial Activity of New Materials Based on Lavender and Basil Essential Oils and Hydroxyapatite Open

Daniela Predoi, Simona Liliana Iconaru, Nicolas Buton, Monica Luminița Badea, Luminița Măruțescu · 2018

This study presents, for the first-time, the results of a study on the hydrodynamic diameter of essential oils (EOs) of basil and lavender in water, and solutions of EOs of basil (B) and lavender (L) and hydroxyapatite (HAp). The possible …

Structural Characterization and Antifungal Studies of Zinc-Doped Hydroxyapatite Coatings Open

Simona Liliana Iconaru, Alina Mihaela Prodan, Nicolas Buton, Daniela Predoi · 2017

The present study is focused on the synthesis, characterization and antifungal evaluation of zinc-doped hydroxyapatite (Zn:HAp) coatings. The Zn:HAp coatings were deposited on a pure Si (Zn:HAp_Si) and Ti (Zn:HAp_Ti) substrate by a sol-gel…

Textural, Structural and Biological Evaluation of Hydroxyapatite Doped with Zinc at Low Concentrations Open

Daniela Predoi, Simona Liliana Iconaru, Aurélien Deniaud, Mireille Chevallet, Isabelle Michaud‐Soret , et al. · 2017

The present work was focused on the synthesis and characterization of hydroxyapatite doped with low concentrations of zinc (Zn:HAp) (0.01 < xZn < 0.05). The incorporation of low concentrations of Zn2+ ions in the hydroxyapatite (HAp) struc…

Nicolas Buton YOU? Author Swipe