Nicolas Dard
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View article: Tunable biomimetic materials elaborated by ice templating and self-assembly of collagen for tubular tissue engineering
Tunable biomimetic materials elaborated by ice templating and self-assembly of collagen for tubular tissue engineering Open
Synthetic tubular grafts currently used in clinical context fail frequently, and the expectations that biomimetic materials could tackle these limitations are high.
View article: Tunable biomimetic materials elaborated by ice templating and self-assembly of collagen for tubular tissue engineering
Tunable biomimetic materials elaborated by ice templating and self-assembly of collagen for tubular tissue engineering Open
Synthetic tubular grafts currently used in clinical context fail frequently, and the expectations that biomimetic materials could tackle these limitations are high. However, developing tubular materials presenting structural, compositional…
View article: Crosstalk and spatiotemporal regulation between stress-induced MAP kinase pathways and pheromone signaling in budding yeast
Crosstalk and spatiotemporal regulation between stress-induced MAP kinase pathways and pheromone signaling in budding yeast Open
Budding yeast, Saccharomyces cerevisiae, has been widely used as a model system to study cellular signaling in response to internal and external cues. Yeast was among the first organisms in which the architecture, feedback mechanism…
View article: Intermittent Hypoxia Increases the Severity of Bleomycin‐Induced Lung Injury in Mice
Intermittent Hypoxia Increases the Severity of Bleomycin‐Induced Lung Injury in Mice Open
Background . Severe obstructive sleep apnea (OSA) with chronic intermittent hypoxia (IH) is common in idiopathic pulmonary fibrosis (IPF). Here, we evaluated the impact of IH on bleomycin‐ (BLM‐) induced pulmonary fibrosis in mice. Methods…
View article: Mesenchymal stem cells reduce hypoxia-induced apoptosis in alveolar epithelial cells by modulating HIF and ROS hypoxic signaling
Mesenchymal stem cells reduce hypoxia-induced apoptosis in alveolar epithelial cells by modulating HIF and ROS hypoxic signaling Open
Distal lung diseases, such as pulmonary fibrosis or acute lung injury, are commonly associated with local alveolar hypoxia that may be deleterious through the stimulation of alveolar epithelial cell (AEC) apoptosis. In various murine model…
View article: Mesenchymal stem cells protect from hypoxia-induced alveolar epithelial-mesenchymal transition
Mesenchymal stem cells protect from hypoxia-induced alveolar epithelial-mesenchymal transition Open
Administration of bone marrow-derived human mesenchymal stem cells (hMSC) reduces lung inflammation, fibrosis, and mortality in animal models of lung injury, by a mechanism not completely understood. We investigated whether hMSC would prev…