Nicolas Dea
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View article: The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgery
The PEG-coated collagen patch Hemopatch® for hemostasis and dural sealing in neurosurgery Open
Background Postoperative cerebrospinal fluid (CSF) leakage and bleeding are major postoperative complications that increase healthcare system costs. The use of Hemopatch® Sealing Hemostat has been shown to reduce the incidence of such post…
View article: Application of deformity principles in the management of spinal neoplasms: A Primer
Application of deformity principles in the management of spinal neoplasms: A Primer Open
View article: The impact of elective spine surgery in Canada for degenerative conditions on patient reported health-related quality of life outcomes
The impact of elective spine surgery in Canada for degenerative conditions on patient reported health-related quality of life outcomes Open
View article: Association of secondhand smoke exposure during pregnancy with left ventricle structure and function in offspring at 4 years old: a prospective birth cohort study
Association of secondhand smoke exposure during pregnancy with left ventricle structure and function in offspring at 4 years old: a prospective birth cohort study Open
Background The association of secondhand smoke exposure during pregnancy with childhood cardiac alterations remains insufficiently elucidated. This study aims to explore the correlation between maternal passive smoking during gestation wit…
View article: Surgical Outcomes and Patient Expectations and Satisfaction in Spine Surgery Stratified by Surgeon Age
Surgical Outcomes and Patient Expectations and Satisfaction in Spine Surgery Stratified by Surgeon Age Open
Importance There is a paucity of data comparing patient-reported outcomes across surgeon age. Prior work has focused on adverse event rates for surgeon age across a variety of surgical procedures. Objective To compare patient-reported outc…
View article: Canadian Association of Radiologists Central Nervous System Diagnostic Imaging Referral Guideline
Canadian Association of Radiologists Central Nervous System Diagnostic Imaging Referral Guideline Open
The Canadian Association of Radiologists (CAR) Central Nervous System Expert Panel is made up of physicians from the disciplines of radiology, emergency medicine, neurosurgery, and neurology, a patient advisor, and an epidemiologist/guidel…
View article: Surgical versus nonsurgical treatment of thoracolumbar burst fractures in neurologically intact patients: a cost-utility analysis
Surgical versus nonsurgical treatment of thoracolumbar burst fractures in neurologically intact patients: a cost-utility analysis Open
Our cost-utility analysis showed surgical management to be cost-effective at 2 years compared to nonoperative management in neurologically intact TL burst fractures from a societal perspective. This finding was maintained through the worki…
View article: Frontline Voice: AO Spine Member Survey Regarding Spine Oncology Knowledge Generation and Translation Needs
Frontline Voice: AO Spine Member Survey Regarding Spine Oncology Knowledge Generation and Translation Needs Open
Study Design cross-sectional survey. Objectives To evaluate AO Spine members’ practices and comfort in managing metastatic and primary spine tumors, explore the use of decision-support and patient assessment tools, and identify knowledge g…
View article: An international expert Delphi consensus on defining the optimal surgical composite outcome (OSCO) in metastatic spine disease
An international expert Delphi consensus on defining the optimal surgical composite outcome (OSCO) in metastatic spine disease Open
View article: Malnutrition in Spine Oncology: Where Are We and What Are We Measuring?
Malnutrition in Spine Oncology: Where Are We and What Are We Measuring? Open
Study design Scoping review. Objective To identify which markers are used as surrogates for malnutrition in metastatic spine disease and which are the most studied outcomes associated with it. Methods A scoping review was performed by sear…
View article: Development of a spine cancer-related pain classification
Development of a spine cancer-related pain classification Open
View article: Overview of Molecular Prognostication for Common Solid Tumor Histologies – What the Surgeon Should Know
Overview of Molecular Prognostication for Common Solid Tumor Histologies – What the Surgeon Should Know Open
Study design Narrative Literature review. Objective To provide a general overview of important molecular markers and targeted therapies for the most common neoplasms (lung, breast, prostate and melanoma) that metastasize to the spine and o…
View article: Advanced Radiotherapy Technologies in Spine Tumors: What the Surgeon Needs to Know
Advanced Radiotherapy Technologies in Spine Tumors: What the Surgeon Needs to Know Open
Study Design Narrative review of existing literature. Objectives Significant technological advancements in radiotherapy planning and delivery have enabled new radiotherapy techniques for the management of spine tumors. The objective of thi…
View article: Latest Developments in Targeted Biological Therapies in the Management of Chordoma and Chondrosarcoma
Latest Developments in Targeted Biological Therapies in the Management of Chordoma and Chondrosarcoma Open
Study Design Systematic review. Objectives The objective of this review paper was to summarize targeted molecular therapy options for spinal chordoma and chondrosarcoma, and to provide an update on the relevant clinical trials open for rec…
View article: Is Navigation a Game Changer in Single Level Transforaminal Lumbar Interbody Fusions (SL‐TLIFs)?
Is Navigation a Game Changer in Single Level Transforaminal Lumbar Interbody Fusions (SL‐TLIFs)? Open
Introduction: Spinal surgery involves different techniques and treatment strategies. Intraoperative navigation by 3D tomography (IoCT) is used to facilitate the insertion of pedicular screws. Better accuracy has been demonstrated by severa…
View article: Canadian Spine Society
Canadian Spine Society Open
View article: Canadian Association of Radiologists Spine Imaging Referral Guideline
Canadian Association of Radiologists Spine Imaging Referral Guideline Open
The Canadian Association of Radiologists (CAR) Spine Expert Panel is made up of physicians from the disciplines of radiology, emergency medicine, neurology, neurosurgery, physiatry, a patient advisor, and an epidemiologist/guideline method…
View article: The Influence of Wait Time on Surgical Outcomes in Elective Lumbar Degenerative Spine Conditions: A Retrospective Multicentre Cohort Study
The Influence of Wait Time on Surgical Outcomes in Elective Lumbar Degenerative Spine Conditions: A Retrospective Multicentre Cohort Study Open
Study Design Retrospective cohort study. Objectives The impact of delayed access to operative treatment on patient reported outcomes (PROs) for lumbar degenerative conditions remains unclear. The goal of this study is to evaluate the assoc…
View article: Validity of a Smartphone App to Objectively Monitor Performance Outcomes in Degenerative Cervical Myelopathy: Preliminary Findings From a Longitudinal Observational Study
Validity of a Smartphone App to Objectively Monitor Performance Outcomes in Degenerative Cervical Myelopathy: Preliminary Findings From a Longitudinal Observational Study Open
Background Developing new clinical measures for degenerative cervical myelopathy (DCM) is an AO Spine RECODE-DCM research priority. Difficulties detecting DCM, and changes in DCM, cause diagnostic and treatment delays in clinical settings …
View article: Preoperative expectations of patients with degenerative cervical myelopathy: an observational study from the Canadian Spine Outcomes and Research Network
Preoperative expectations of patients with degenerative cervical myelopathy: an observational study from the Canadian Spine Outcomes and Research Network Open
View article: Contemporary trends in the incidence and timing of spinal metastases: A population-based study
Contemporary trends in the incidence and timing of spinal metastases: A population-based study Open
Background Spinal metastases are a significant complication of advanced cancer. In this study, we assess temporal trends in the incidence and timing of spinal metastases and examine underlying patient demographics and primary cancer associ…
View article: Gender and Sex Differences in Health-related Quality of Life, Clinical Outcomes and Survival after Treatment of Metastatic Spine Disease
Gender and Sex Differences in Health-related Quality of Life, Clinical Outcomes and Survival after Treatment of Metastatic Spine Disease Open
Study Design. Retrospective review of prospective, multicenter and international cohort study. Objective. To describe the effect of gender on HRQoL, clinical outcomes and survival for patients with spinal metastases treated with either sur…
View article: Management of mild degenerative cervical myelopathy and asymptomatic spinal cord compression: an international survey
Management of mild degenerative cervical myelopathy and asymptomatic spinal cord compression: an international survey Open
Study design Cross-sectional survey. Objective Currently there is limited evidence and guidance on the management of mild degenerative cervical myelopathy (DCM) and asymptomatic spinal cord compression (ASCC). Anecdotal evidence suggest va…
View article: Pattern of neurological recovery in persons with an acute cervical spinal cord injury over the first 14 days post injury
Pattern of neurological recovery in persons with an acute cervical spinal cord injury over the first 14 days post injury Open
Introduction Following a traumatic spinal cord injury (SCI) it is critical to document the level and severity of injury. Neurological recovery occurs dynamically after injury and a baseline neurological exam offers a snapshot of the patien…
View article: Effectiveness of prophylactic intranasal photodynamic disinfection therapy and chlorhexidine gluconate body wipes for surgical site infection prophylaxis in adult spine surgery
Effectiveness of prophylactic intranasal photodynamic disinfection therapy and chlorhexidine gluconate body wipes for surgical site infection prophylaxis in adult spine surgery Open
Preoperative nPDT-CHG administration is an effective prophylactic strategy for spinal SSIs, with significant cost savings. Given its rapid action, minimal risk of antimicrobial resistance, broad-spectrum activity and high compliance rate, …
View article: Validity of a Smartphone App to Objectively Monitor Performance Outcomes in Degenerative Cervical Myelopathy: Preliminary Findings From a Longitudinal Observational Study (Preprint)
Validity of a Smartphone App to Objectively Monitor Performance Outcomes in Degenerative Cervical Myelopathy: Preliminary Findings From a Longitudinal Observational Study (Preprint) Open
BACKGROUND Developing new clinical measures for degenerative cervical myelopathy (DCM) is an AO Spine RECODE-DCM research priority. Difficulties detecting DCM, and changes in DCM, cause diagnostic and treatment delays in clinical settings…
View article: Validity of a smartphone app to objectively monitor performance outcomes in degenerative cervical myelopathy: an observational study
Validity of a smartphone app to objectively monitor performance outcomes in degenerative cervical myelopathy: an observational study Open
Objectives To assess the validity of MoveMed, a battery of performance outcome measures performed using a mobile phone application, in the measurement of degenerative cervical myelopathy (DCM). Design Prospective observational study. Setti…
View article: Incidence and prevalence of traumatic spinal cord injury in Canada using health administrative data
Incidence and prevalence of traumatic spinal cord injury in Canada using health administrative data Open
Introduction Incidence and prevalence data are needed for the planning, funding, delivery and evaluation of injury prevention and health care programs. The objective of this study was to estimate the Canadian traumatic spinal cord injury (…
View article: Impact of Specialized Versus Non-Specialized Acute Hospital Care on Survival Among Patients With Acute Incomplete Traumatic Spinal Cord Injuries: A Population-Based Observational Study from British Columbia, Canada
Impact of Specialized Versus Non-Specialized Acute Hospital Care on Survival Among Patients With Acute Incomplete Traumatic Spinal Cord Injuries: A Population-Based Observational Study from British Columbia, Canada Open
Given the complexity of care necessitated after an acute traumatic spinal cord injury (SCI), it seems intuitively beneficial for such care to be delivered at hospitals with specialized SCI expertise. Demonstrating these benefits is not str…
View article: F.5 Spinal column and spinal cord injuries secondary to mountain biking accidents: a 15-year review at a provincial spine referral centre
F.5 Spinal column and spinal cord injuries secondary to mountain biking accidents: a 15-year review at a provincial spine referral centre Open
Background: Mountain biking (MTB) is an increasingly popular sport that has been associated with serious spinal injuries, which can have devastating effects on patients and significant impacts on healthcare resources. Herein, we characteri…