Explanipedia

Safety and efficacy of a lattice-tip catheter for ventricular arrhythmia ablation: the AFFERA Ventricular Arrhythmia Ablation Registry (AVAAR) Open

Frédéric Sacher, Andrea Sarkozy, Helmut Pürerfellner, Alexandra Steyer, Jonathan Lyne , et al. · 2025

Aims The feasibility and safety of the lattice-tip catheter for ventricular arrhythmia (VA) ablation in humans remain largely unknown. This study aimed to assess feasibility, safety profile as well as patient outcomes after VA ablation wit…

Regionalization of the atria for 3D electroanatomical mapping, cardiac imaging, and computational modelling: a clinical consensus statement of the European Heart Rhythm Association and the European Association of Cardiovascular Imaging of the ESC Open

Till Althoff, Robert H. Anderson, Christian Goetz, Steffen E. Petersen, Patricia Martínez Díaz , et al. · 2025

This clinical consensus document proposes standardized atrial segments for 3D imaging, electroanatomical mapping and computational modelling, based on anatomical, electrophysiological and clinical considerations, with precise definitions o…

Defibrillation Testing During Implantation of Subcutaneous Implantable Cardioverter Defibrillators Open

Fawzi Kerkouri, Christelle Marquié, Mina Ait Saïd, W. Amara, Frédéric Anselme , et al. · 2025

Safety of propofol use for general anaesthesia in Brugada syndrome patients: a 15-year experience Open

Romain Tixier, Elise Langouet, Josselin Duchâteau, Nicolas Derval, Thomas Pambrun , et al. · 2025

Imaging‐Aided VT Ablation. Long‐Term Results From a Pilot Study Open

Benjamin Sacristan, Hubert Cochet, Benjamin Bouyer, Romain Tixier, Josselin Duchateau , et al. · 2025

Background Ventricular tachycardia (VT) ablation has become a cornerstone of patient care, especially for post‐MI VT. Several strategies have proven effective for achieving rhythm control in this population, but the workflow is highly vari…

Catheter ablation in congenital heart diseases: a French nationwide study Open

Victor Waldmann, Guillaume Duthoit, Jean-Luc Pasquié, Laure Champ‐Rigot, Mathieu Albertini , et al. · 2025

Background and Aims Current evidence on catheter ablation for patients with congenital heart disease (CHD) is derived from small, retrospective studies. This study aims to provide insights from a nationwide contemporary registry. Methods T…

Marshall-Plan Ablation Strategy Versus Pulmonary Vein Isolation in Persistent AF: A Randomized Controlled Trial Open

Nicolas Derval, Romain Tixier, Josselin Duchâteau, Xavier Bouteiller, Timothé Loock , et al. · 2025

BACKGROUND: Beyond pulmonary vein (PV) isolation, the optimal ablation strategy for persistent atrial fibrillation (AF) remains poorly defined. The purpose of this study was to compare 2 ablation strategies in the treatment of patients wit…

Systematic replication of the Marshall-PLAN lesion set using two commercially-available PFA systems: a prospective feasibility analysis Open

Allan Plant, Kinan Kneizeh, John Fitzgerald, Laurens Verhaeghe, Masaaki Yokoyama , et al. · 2025

Introduction A strategy of systematic Marshall bundle elimination, PVI, and linear ablation (the Marshall-PLAN) has shown promise in improving the outcomes of patients undergoing ablation for persistent AF. Concomitant with development of …

Repeat procedures after pulsed field ablation for atrial fibrillation: <i>MANIFEST-REDO</i> study Open

Douglas S. Scherr, Mohit K. Turagam, Philippe Maury, Yuri Blaauw, Pepijn van der Voort , et al. · 2025

Aims Initial clinical studies of pulsed field ablation (PFA) to treat atrial fibrillation (AF) indicated a >90% durability rate of pulmonary vein isolation (PVI). However, these studies were largely conducted in single centres and invol…

2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation Open

Stylianos Tzeis, Edward P. Gerstenfeld, Jonathan M. Kalman, Eduardo Saad, Alireza Sepehri Shamloo , et al. · 2024

In the last three decades, ablation of atrial fibrillation (AF) has become an evidence‐based safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007, the first joint expert consensus document was issued, gui…

Anatomical Treatment Strategies for Persistent Atrial Fibrillation with Ethanol Infusion within the Vein of Marshall—Current Challenges and Future Directions Open

Masaaki Yokoyama, Konstantinos Vlachos, Chizute Ogbedeh, Ciro Ascione, Christopher Kowalewski , et al. · 2024

Currently, pulmonary vein isolation (PVI) is the gold standard in catheter ablation for atrial fibrillation (AF). However, PVI alone may be insufficient in the management of persistent AF, and complementary methods are being explored. One …

Impact of vein of Marshall ethanol infusion on achieving floor line block: Is it possible to create a floor line with vein of Marshall ethanol infusion? Open

Masaaki Yokoyama, Ciro Ascione, Christopher Kowalewski, Thomas Pambrun, Pierre Jaı̈s , et al. · 2024

Safety and Effectiveness of Pulsed Field Ablation for Atrial Fibrillation in Patients With Heart Failure Open

Mohit K. Turagam, Petr Neužil, Boris Schmidt, Tobias Reichlin, Kars Neven , et al. · 2024

Impact of additional pulsed field ablation in unsuccessful radiofrequency linear lesions -acute and chronic data Open

M. Yokoyama, Konstantinos Vlachos, Cezary Kowaléwski, Ciro Ascione, N. Moussaoui , et al. · 2024

Background Performing linear ablation such as roof line, inferior line in the posterior part of LA and posterior mitral isthmus (MI) line in addition to PVI is one of the strategies for treating persistent atrial fibrillation. However, rem…

Computed tomography as a predictive tool for ventricular tachycardia Open

Cezary Kowaléwski, Marta Nuñez‐Garcia, Xavier Bouteiller, Konstantinos Vlachos, Karim Bénali , et al. · 2024

Background Sudden cardiac death is the main cause of mortality worldwide. It is often linked with ventricular tachycardia (VT). To prevent VT, high-risk patients are typically equipped with intracardiac defibrillators (ICDs). Currently, le…

Characterization and clinical significance of hemolysis after pulsed-field ablation for atrial fibrillation: insights from a multicentric analysis Open

Miruna Popa, Sandrine Venier, Roberto Menè, Domenico G. Della Rocca, Frédéric Sacher , et al. · 2024

Background Pulsed-field ablation is a novel non-thermal ablation modality which is being increasingly used in clinical practice for the treatment of atrial fibrillation (AF). While the susceptibility of erythrocytes to electroporation is w…

Comparing pulsed field electroporation and radiofrequency ablation for the treatment of paroxysmal atrial fibrillation: design and rationale of the BEAT PAROX-AF randomized clinical trial Open

Nico Erhard, Éric Frison, Julien Asselineau, Besma Aouar, Serge Bovéda , et al. · 2024

Aims Using thermal-based energy sources [radiofrequency (RF) energy/cryo energy] for catheter ablation is considered effective and safe when performing pulmonary vein isolation (PVI) in patients with paroxysmal atrial fibrillation (AF). Ho…

2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation Open

Stylianos Tzeis, Edward P. Gerstenfeld, Jonathan M. Kalman, Eduardo Saad, Alireza Sepehri Shamloo , et al. · 2024

2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation Open

Stylianos Tzeis, Edward P. Gerstenfeld, Jonathan M. Kalman, Eduardo Saad, Alireza Sepehri Shamloo , et al. · 2024

2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation Open

Stylianos Tzeis, Edward P. Gerstenfeld, Jonathan M. Kalman, Eduardo Saad, Alireza Sepehri Shamloo , et al. · 2024

In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007, the first joint expert consensus document was issued, gui…

Isolation of left pulmonary veins by ethanol injection in the vein of Marshall Open

Christopher Kowalewski, Nicolas Derval, Thomas Pambrun, Josselin Duchâteau, Konstantinos Vlachos , et al. · 2024

The vein of Marshall is localized on the posterior part of the left atrium. It drains the blood from the left atrial endocardium to the coronary sinus. There are epicardial fibers which travel along the vein of Marshall. The endocardial ra…

Effects of pulsed field ablation on the parasympathetic nervous system: a mechanistic approach Open

Christopher Kowalewski, Benjamin Bouyer, Ciro Ascione, Konstantinos Vlachos, Karim Bénali , et al. · 2024

Background: Pulsed field ablation (PFA) is a novel technique for pulmonary vein isolation in atrial fibrillation management. Notably, asystole episodes of varying durations have been observed during electroporation, but the underlying mech…

Table of Contents Open

Maurits A. Allessie, Jan‐Per Wenzel, Marc D. Lemoine, Laura Rottner, Ilaria My , et al. · 2024

Impact of Left Atrial Posterior Wall Ablation During Pulsed-Field Ablation for Persistent Atrial Fibrillation Open

Mohit K. Turagam, Petr Neužil, Boris Schmidt, Tobias Reichlin, Kars Neven , et al. · 2024

Clinical Outcomes by Sex After Pulsed Field Ablation of Atrial Fibrillation Open

Mohit K. Turagam, Petr Neužil, Boris Schmidt, Tobias Reichlin, Kars Neven , et al. · 2023

Importance Previous studies evaluating the association of patient sex with clinical outcomes using conventional thermal ablative modalities for atrial fibrillation (AF) such as radiofrequency or cryoablation are controversial due to mixed …

Impact of filter configurations on bipolar EGMs: An optimal filter setting for identifying VT substrates Open

Masateru Takigawa, Frédéric Sacher, Claire Martin, Ghassen Cheniti, Josselin Duchâteau , et al. · 2023

Background The impact of filtering on bipolar electrograms (EGMs) has not been systematically examined. We tried to clarify the optimal filter configuration for ventricular tachycardia (VT) ablation. Methods Fifteen patients with VT were i…

Detailed analysis of tachycardia cycle length aids diagnosis of the mechanism and location of atrial tachycardias Open

Masateru Takigawa, Tsukasa Kamakura, Claire Martin, Nicolas Derval, Ghassen Cheniti , et al. · 2023

Aims Although the mechanism of an atrial tachycardia (AT) can usually be elucidated using modern high-resolution mapping systems, it would be helpful if the AT mechanism and circuit could be predicted before initiating mapping. Objective W…

Omnipolar versus bipolar mapping to guide ventricular tachycardia ablation Open

Ciro Ascione, Christopher Kowalewski, Marco Bergonti, Masaaki Yokoyama, Cinzia Monaco , et al. · 2023

Electrophysiological study prior to planned pulmonary valve replacement in patients with repaired tetralogy of Fallot Open

Benjamin Bouyer, Zakaria Jalal, F. Daniel Ramirez, Nicolas Derval, Xavier Iriart , et al. · 2023

Aim Ventricular arrhythmias (VAs) are the most common cause of death in patients with repaired Tetralogy of Fallot (rTOF). However, risk stratifying remains challenging. We examined outcomes following programmed ventricular stimulation (PV…

Omnipolar mapping in ventricular tachycardia: will it be a game changer? Open

Ciro Ascione, Cezary Kowaléwski, Benjamin Bouyer, Romain Tixier, Rémi Chauvel , et al. · 2023

Funding Acknowledgements Type of funding sources: None. Background Ventricular tachycardias(VT) are life-theatening cardiac arrhythmias. Catheter ablation, the standard approach to VT is relying heavily on maps depicting intracardiac signa…

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