B.N. Díaz-Chico
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View article: Chemical-proteomics Identify Peroxiredoxin-1 as an Actionable Target in Triple-negative Breast Cancer
Chemical-proteomics Identify Peroxiredoxin-1 as an Actionable Target in Triple-negative Breast Cancer Open
Triple-negative breast cancer (TNBC) is difficult to treat; therefore, the development of drugs directed against its oncogenic vulnerabilities is a desirable goal. Herein, we report the antitumor effects of CM728, a novel quinone-fused oxa…
View article: A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells
A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells Open
BCR-ABL1-STAT5 is an oncogenic signaling pathway in human chronic myelogenous leukemia (CML) and it represents a valid target for anti-CML drug design. Resistance to direct BCR-ABL1 inhibitors is a common clinical issue, so STAT5 inhibitio…
View article: Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages
Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages Open
The liver X receptors α and β (LXRα and LXRβ) are oxysterol-activated transcription factors that coordinately regulate gene expression that is important for cholesterol and fatty acid metabolism. In addition to their roles in lipid metabol…
View article: Correction: CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia
Correction: CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia Open
[This corrects the article DOI: 10.18632/oncotarget.11425.].
View article: Androgen receptor gene polymorphisms and maximal fat oxidation in men. A longitudinal study.
Androgen receptor gene polymorphisms and maximal fat oxidation in men. A longitudinal study. Open
Introduction: The aims of this study were i) to evaluate if extreme CAG and GGN repeat polymorphisms of the androgen receptors (AR) influence body fat mass, its regional distribution, resting metabolic rate (RMR), resting and maximal fat o…
View article: CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia
CM363, a novel naphthoquinone derivative which acts as multikinase modulator and overcomes imatinib resistance in chronic myelogenous leukemia Open
[This corrects the article DOI: 10.18632/oncotarget.11425.].