Nicolas Gambier
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View article: Detection of ketamine in the oral fluid of drivers in northeastern France during the years 2020–2023
Detection of ketamine in the oral fluid of drivers in northeastern France during the years 2020–2023 Open
Background and Objectives Ketamine is a psychoactive substance used for its stimulant and hallucinogenic properties. As the use of ketamine may lead to impaired driving, we aimed to assess the occurrence of ketamine in the driving populati…
View article: Trends in fatal poisoning among medical users of analgesics in France from 2013 to 2022: an analysis of the DTA register
Trends in fatal poisoning among medical users of analgesics in France from 2013 to 2022: an analysis of the DTA register Open
View article: A biological pharmacology network to secure the risk of drug–drug interaction with nirmatrelvir/ritonavir
A biological pharmacology network to secure the risk of drug–drug interaction with nirmatrelvir/ritonavir Open
View article: Evaluation of amphetamines diffusion in hair after contact with amphetamines-containing blood
Evaluation of amphetamines diffusion in hair after contact with amphetamines-containing blood Open
View article: In vitro stability study of 10 beta‐lactam antibiotics in human plasma samples
In vitro stability study of 10 beta‐lactam antibiotics in human plasma samples Open
Background and Objectives Beta‐lactam antibiotics are reported for some of them to be subject to a rapid degradation in infusion solutions and in human blood samples. However, the current data of stability available in blood samples are li…
View article: Immunological detection of hexahydrocannabinol (HHC) in oral fluid
Immunological detection of hexahydrocannabinol (HHC) in oral fluid Open
International audience
View article: Therapeutic drug monitoring as an essential tool to ensure clozapine efficacy and prevent its toxicity in smokers: a case report
Therapeutic drug monitoring as an essential tool to ensure clozapine efficacy and prevent its toxicity in smokers: a case report Open
View article: Trends in Fatal Poisoning Among Drug Users in France From 2011 to 2021
Trends in Fatal Poisoning Among Drug Users in France From 2011 to 2021 Open
Importance The DRAMES (Décès en Relation avec l’Abus de Médicaments Et de Substances) register is a database of drug-related deaths with the aim of identifying the psychoactive substances associated with and estimating the trends in these …
View article: Immune thrombocytopenia and pregnancy: an exposed/nonexposed cohort study
Immune thrombocytopenia and pregnancy: an exposed/nonexposed cohort study Open
The risk of immune thrombocytopenia (ITP) worsening during pregnancy and neonatal ITP (NITP) have never been prospectively studied. We included 180 pregnant and 168 nonpregnant women with ITP in a prospective, multicenter, observational co…
View article: Rat synovial tissue and blood rapamycin pharmacokinetics after intra-articular injection of free solution or nanoparticles vs free rapamycin intravenous shot
Rat synovial tissue and blood rapamycin pharmacokinetics after intra-articular injection of free solution or nanoparticles vs free rapamycin intravenous shot Open
View article: Impaired Pharmacokinetics of Amiodarone under Veno-Venous Extracorporeal Membrane Oxygenation: From Bench to Bedside
Impaired Pharmacokinetics of Amiodarone under Veno-Venous Extracorporeal Membrane Oxygenation: From Bench to Bedside Open
Background: Adjusting drug therapy under veno-venous extracorporeal membrane oxygenation (VV ECMO) is challenging. Although impaired pharmacokinetics (PK) under VV ECMO have been reported for sedative drugs and antibiotics, data about amio…
View article: Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group
Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group Open
View article: Rapamycin-loaded Poly(lactic-co-glycolic) acid nanoparticles: Preparation, characterization, and in vitro toxicity study for potential intra-articular injection
Rapamycin-loaded Poly(lactic-co-glycolic) acid nanoparticles: Preparation, characterization, and in vitro toxicity study for potential intra-articular injection Open
View article: SporTRIA study—a multicentre trial protocol for excretion kinetics of triamcinolone acetonide following sport-related intra-articular injections in knees: definitions of the washout periods
SporTRIA study—a multicentre trial protocol for excretion kinetics of triamcinolone acetonide following sport-related intra-articular injections in knees: definitions of the washout periods Open
Introduction Intra-articular (IA) and peri-articular glucocorticoid (GC) injections are common in sports medicine. However, from 1 January 2022, all injectable GC routes (including IA administration) will be prohibited in-competition by Wo…
View article: Pneumomédiastin secondaire à une infection de type SRAS-nCOV-2
Pneumomédiastin secondaire à une infection de type SRAS-nCOV-2 Open
View article: Intérêt du génotypage du cytochrome P450 2D6 en pratique courante dans le traitement de la dépression
Intérêt du génotypage du cytochrome P450 2D6 en pratique courante dans le traitement de la dépression Open
View article: Multiplex detection of 14 fentanyl analogues and U-47700 in biological samples: Application to a panel of French hospitalized patients
Multiplex detection of 14 fentanyl analogues and U-47700 in biological samples: Application to a panel of French hospitalized patients Open
View article: Temocillin dosage adjustment in a preterm infant with severe renal disease: a case report
Temocillin dosage adjustment in a preterm infant with severe renal disease: a case report Open
Background Temocillin is a carboxypenicillin antibiotic indicated in complicated urinary tract infections due to susceptible ESBL-producing Enterobacteriaceae. While temocillin therapeutic schemes for adult patients with normal or impaired…
View article: Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer
Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer Open
The Idylla system does not reach as high sensitivity as assays like ddPCR but has an equivalent sensitivity to modified NGS technics with a lower cost and a lower time to results. These data allowed to consider the Idylla system in a routi…
View article: Observational, Prospective Single-Center Study of Antibiotic Prophylaxis with High-Dose Cefoxitin in Bariatric Surgery
Observational, Prospective Single-Center Study of Antibiotic Prophylaxis with High-Dose Cefoxitin in Bariatric Surgery Open
The optimal dose of cefoxitin for antibiotic prophylaxis in obese patients remains uncertain. We evaluated the adequacy of a 4-g dosing regimen of cefoxitin against the most common pathogens that infect patients undergoing bariatric surger…
View article: Paracetamol Misuse and Dental Pain: Results from the French Observational DAntaLor Study
Paracetamol Misuse and Dental Pain: Results from the French Observational DAntaLor Study Open
Patients with dental pain are at risk of paracetamol overdose and hepatotoxicity.
View article: Intravenous single administration of amiodarone and breastfeeding
Intravenous single administration of amiodarone and breastfeeding Open
Amiodarone treatment is contraindicated during breastfeeding. As the regional pharmacovigilance centre, we were contacted for information relative to the possibility of breastfeeding after single intravenous administration of 450 mg amioda…
View article: Impact of reduced exposure to calcineurin inhibitors on the development of de novo DSA: a cohort of non-immunized first kidney graft recipients between 2007 and 2014
Impact of reduced exposure to calcineurin inhibitors on the development of de novo DSA: a cohort of non-immunized first kidney graft recipients between 2007 and 2014 Open
View article: High-Dose Mitotane-Induced Encephalopathy in the Treatment of Adrenocortical Carcinoma
High-Dose Mitotane-Induced Encephalopathy in the Treatment of Adrenocortical Carcinoma Open
In response to the recently published article by Reidy-Lagunes et al., which deals with clinical response to mitotane treatment in advanced adrenocortical carcinoma and the toxicity associated with this treatment, this letter to the editor…
View article: Good renal and vital prognosis of metformin induced Lactic acidosis
Good renal and vital prognosis of metformin induced Lactic acidosis Open
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
View article: Effect of esomeprazole on the oral absorption of dasatinib in a patient with Philadelphia‐positive acute lymphoblastic leukemia
Effect of esomeprazole on the oral absorption of dasatinib in a patient with Philadelphia‐positive acute lymphoblastic leukemia Open
International audience