Nicolas Langbour
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View article: Cognitive electroencephalographic potentials evoked by words as markers of the severity of the pathology and resistance to treatment in obsessive-compulsive disorder.
Cognitive electroencephalographic potentials evoked by words as markers of the severity of the pathology and resistance to treatment in obsessive-compulsive disorder. Open
View article: Investigating brain structure and tDCS response in obsessive-compulsive disorder
Investigating brain structure and tDCS response in obsessive-compulsive disorder Open
International audience
View article: Treating refractory obsessive compulsive disorder with cathodal transcranial direct current stimulation over the supplementary motor area: a large multisite randomized sham-controlled double-blind study
Treating refractory obsessive compulsive disorder with cathodal transcranial direct current stimulation over the supplementary motor area: a large multisite randomized sham-controlled double-blind study Open
Background The present study evaluated the therapeutic efficacy and tolerability of 10 transcranial direct current stimulation (tDCS) sessions in treatment-resistance obsessive-compulsive disorder (OCD) patients using a multisite double-bl…
View article: Usefulness of thalamic beta activity for closed-loop therapy in essential tremor
Usefulness of thalamic beta activity for closed-loop therapy in essential tremor Open
View article: Brainstim, a tool for automated personalized tDCS computational modeling based on PyAnsys
Brainstim, a tool for automated personalized tDCS computational modeling based on PyAnsys Open
View article: Evaluation of the effects of non-invasive neurostimulation technique on self-reported quality of life and disability in treatment-resistant obsessive-compulsive patients
Evaluation of the effects of non-invasive neurostimulation technique on self-reported quality of life and disability in treatment-resistant obsessive-compulsive patients Open
View article: Treatment of resistant depression with high-frequency rTMS over the left DLPFC: Clinical and neuroimaging biomarkers
Treatment of resistant depression with high-frequency rTMS over the left DLPFC: Clinical and neuroimaging biomarkers Open
View article: Efficacy of Repetitive Transcranial Magnetic Stimulation in depressive patients on suicidal idea: a retrospective analysis of a clinical large sample
Efficacy of Repetitive Transcranial Magnetic Stimulation in depressive patients on suicidal idea: a retrospective analysis of a clinical large sample Open
View article: Baseline Clinical and Neuroimaging Biomarkers of Treatment Response to High-Frequency rTMS Over the Left DLPFC for Resistant Depression
Baseline Clinical and Neuroimaging Biomarkers of Treatment Response to High-Frequency rTMS Over the Left DLPFC for Resistant Depression Open
Background Repetitive transcranial magnetic stimulation (rTMS) has proven to be an efficient treatment option for patients with treatment-resistant depression (TRD). However, the success rate of this method is still low, and the treatment …
View article: Evolution of obsessive and compulsive symptoms over two years of deep brain stimulation cessation and explantation, after fourteen years of continuous stimulation for treatment-resistant obsessive-compulsive disorder. A case report
Evolution of obsessive and compulsive symptoms over two years of deep brain stimulation cessation and explantation, after fourteen years of continuous stimulation for treatment-resistant obsessive-compulsive disorder. A case report Open
International audience
View article: Preliminary Evidence That the Short Allele of 5-HTTLPR Moderates the Association of Psychiatric Symptom Severity on Suicide Attempt: The Example in Obsessive-Compulsive Disorder
Preliminary Evidence That the Short Allele of 5-HTTLPR Moderates the Association of Psychiatric Symptom Severity on Suicide Attempt: The Example in Obsessive-Compulsive Disorder Open
Background The severity of symptoms represents an important source of distress in patients with a psychiatric disease. However, the extent to which this endogenous stress factor interacts with genetic vulnerability factors for predicting s…
View article: Exposure to High Precariousness Prevalence Negatively Impacts Drug Prescriptions of General Practitioners to Precarious and Non-Precarious Populations: A Retrospective Pharmaco-Epidemiological Study
Exposure to High Precariousness Prevalence Negatively Impacts Drug Prescriptions of General Practitioners to Precarious and Non-Precarious Populations: A Retrospective Pharmaco-Epidemiological Study Open
(1) Background: Precarious patients are more difficult to care for due to low literacy rates and poor adherence to treatment and hospitalization. These difficulties have detrimental effects on general practitioners (GPs), deteriorating med…
View article: Competition, Conflict and Change of Mind: A Role of GABAergic Inhibition in the Primary Motor Cortex
Competition, Conflict and Change of Mind: A Role of GABAergic Inhibition in the Primary Motor Cortex Open
Deciding between different voluntary movements implies a continuous control of the competition between potential actions. Many theories postulate a leading role of prefrontal cortices in this executive function, but strong evidence exists …
View article: Erratum to: Striatal and cerebellar vesicular acetylcholine transporter expression is disrupted in human DYT1 dystonia
Erratum to: Striatal and cerebellar vesicular acetylcholine transporter expression is disrupted in human DYT1 dystonia Open
International audience
View article: Échelle d’évaluation de l’insight dans l’alcoolisme : validation de la version française du questionnaire Hanil Alcohol Insight Scale (HAIS)
Échelle d’évaluation de l’insight dans l’alcoolisme : validation de la version française du questionnaire Hanil Alcohol Insight Scale (HAIS) Open
En psychiatrie clinique, le concept d’insight désigne la perception et la conscience qu’a un patient de son trouble. Son déficit dans le contexte de l’addiction à l’alcool se traduit par une incapacité à reconnaître l’addiction, le déni de…
View article: Striatal and cerebellar vesicular acetylcholine transporter expression is disrupted in human DYT1 dystonia
Striatal and cerebellar vesicular acetylcholine transporter expression is disrupted in human DYT1 dystonia Open
Early-onset torsion dystonia (TOR1A/DYT1) is a devastating hereditary motor disorder whose pathophysiology remains unclear. Studies in transgenic mice suggested abnormal cholinergic transmission in the putamen, but this has not yet been de…
View article: Treating refractory obsessive–compulsive disorder with transcranial direct current stimulation: An open label study
Treating refractory obsessive–compulsive disorder with transcranial direct current stimulation: An open label study Open
Background Obsessive–compulsive disorder (OCD) is a complex disorder with 40%–60% of patients' refractory to treatment. Transcranial direct current stimulation (tDCS) has been shown to induce potent and long‐lasting effects on cortical exc…
View article: Predicting relapse in patients with severe alcohol use disorder: The role of alcohol insight and implicit alcohol associations
Predicting relapse in patients with severe alcohol use disorder: The role of alcohol insight and implicit alcohol associations Open
View article: The Relation Between Empathy and Insight in Psychiatric Disorders: Phenomenological, Etiological, and Neuro-Functional Mechanisms
The Relation Between Empathy and Insight in Psychiatric Disorders: Phenomenological, Etiological, and Neuro-Functional Mechanisms Open
Lack of insight, i.e., unawareness of one's mental illness, is frequently encountered in psychiatric conditions. Insight is the capacity to recognize (psychical insight) and accept one's mental illness (emotional insight). Insight growth n…
View article: Continuous theta burst stimulation over the supplementary motor area in refractory obsessive-compulsive disorder treatment: A randomized sham-controlled trial
Continuous theta burst stimulation over the supplementary motor area in refractory obsessive-compulsive disorder treatment: A randomized sham-controlled trial Open
View article: Checking behavior in rhesus monkeys is related to anxiety and frontal activity
Checking behavior in rhesus monkeys is related to anxiety and frontal activity Open
When facing doubt, humans can go back over a performed action in order to optimize subsequent performance. The present study aimed to establish and characterize physiological doubt and checking behavior in non-human primates (NHP). We trai…
View article: Identifying Oneself with the Face of Someone Else Impairs the Egocentered Visuo-spatial Mechanisms: A New Double Mirror Paradigm to Study Self–other Distinction and Interaction
Identifying Oneself with the Face of Someone Else Impairs the Egocentered Visuo-spatial Mechanisms: A New Double Mirror Paradigm to Study Self–other Distinction and Interaction Open
Looking at our face in a mirror is one of the strongest phenomenological experiences of the Self in which we need to identify the face as reflected in the mirror as belonging to us. Recent behavioral and neuroimaging studies reported that …
View article: The Cortical Processing of Sensorimotor Sequences is Disrupted in Writer's Cramp
The Cortical Processing of Sensorimotor Sequences is Disrupted in Writer's Cramp Open
Evidence for pre-existing abnormalities in the sensory and motor systems has been previously reported in writer's cramp (WC). However, the processing of somatosensory information during motor planning has received little attention. We hypo…
View article: Electrophysiological Correlates of a Versatile Executive Control System in the Monkey Anterior Cingulate Cortex
Electrophysiological Correlates of a Versatile Executive Control System in the Monkey Anterior Cingulate Cortex Open
When a subject faces conflicting situations, decision-making becomes uncertain. The human dorsal anterior cingulate cortex (dACC) has been repeatedly implicated in the monitoring of such situations, and its neural activity is thought to be…