Jorge Mendoza
YOU?
Author Swipe
View article: COVID-19 and its Impact on the Development of Digital Competencies at the Higher Level. A Systematic review of the Literature
COVID-19 and its Impact on the Development of Digital Competencies at the Higher Level. A Systematic review of the Literature Open
The COVID-19 pandemic generated an unparalleled change in higher education, driving a transition towards digital teaching. This transformation revealed significant gaps in the digital competencies of students and teachers, essential for ad…
View article: Stabilized Hypochlorous Acid to Prevent Adipose Graft Infection in Body Contouring: A Clinical Study of 1902 Muscle Groups
Stabilized Hypochlorous Acid to Prevent Adipose Graft Infection in Body Contouring: A Clinical Study of 1902 Muscle Groups Open
Background Despite the general safety of liposuction and fat grafting procedures, surgical-site infections (SSIs) remain a significant concern. These infections, ranging from minor to severe, can arise from various sources and pose a subst…
View article: Addressing Hypertension and Diabetes through Community-Engaged Systems (ANDES) in Puno, Peru: rationale and study protocol for a hybrid type 2 effectiveness and implementation randomized controlled trial
Addressing Hypertension and Diabetes through Community-Engaged Systems (ANDES) in Puno, Peru: rationale and study protocol for a hybrid type 2 effectiveness and implementation randomized controlled trial Open
ClinicalTrials.gov, ID: NCT05524987 , Addressing Hypertension and Diabetes through Community-Engaged Systems in Puno, Peru (ANDES study), prospectively registered on September 1, 2021.
View article: P033 Unrevealing new potential key mechanisms implicated in inflammatory bowel disease by multiomic approach
P033 Unrevealing new potential key mechanisms implicated in inflammatory bowel disease by multiomic approach Open
Background Inflammatory bowel diseases (IBD), comprising Crohn´s disease (CD) and ulcerative colitis (UC), are characterised by chronic, relapsing and remitting inflammation of the gastrointestinal tract. Despite significant efforts to und…
View article: Medication adherence among people living with hypertension and diabetes in Puno, Peru: A secondary analysis of formative data of the ANDES trial
Medication adherence among people living with hypertension and diabetes in Puno, Peru: A secondary analysis of formative data of the ANDES trial Open
Background Hypertension is the leading modifiable risk factor for premature death globally despite the existence of evidence-based and cost-effective treatments. Medication nonadherence is cited as the main cause of treatment failure for h…
View article: Enhanced Robustness of the Mouse Retinal Circadian Clock Upon Inherited Retina Degeneration
Enhanced Robustness of the Mouse Retinal Circadian Clock Upon Inherited Retina Degeneration Open
Daily biological rhythms are fundamental to retinal physiology and visual function. They are generated by a local circadian clock composed of a network of cell type/layer-specific, coupled oscillators. Animal models of retinal degeneration…
View article: Nighttime Light Hurts Mammalian Physiology: What Diurnal Rodent Models Are Telling Us
Nighttime Light Hurts Mammalian Physiology: What Diurnal Rodent Models Are Telling Us Open
Natural sunlight permits organisms to synchronize their physiology to the external world. However, in current times, natural sunlight has been replaced by artificial light in both day and nighttime. While in the daytime, indoor artificial …
View article: Distinctive properties of cones in the retinal clock and the circadian system
Distinctive properties of cones in the retinal clock and the circadian system Open
The circadian system is a hierarchical network of cell and tissue-specific oscillators synchronized to the environmental light/dark cycle. Entrainment is mediated by the retina through diverse photosensitive cells and pigments. The retina …
View article: Metabolic Effects of Light at Night are Time‐ and Wavelength‐Dependent in Rats
Metabolic Effects of Light at Night are Time‐ and Wavelength‐Dependent in Rats Open
Objective Intrinsically photosensitive retinal ganglion cells are most sensitive to short wavelengths and reach brain regions that modulate biological rhythms and energy metabolism. The increased exposure nowadays to artificial light at ni…
View article: Charger Location in Electric Bus Networks
Charger Location in Electric Bus Networks Open
International audience
View article: Blue light at night acutely impairs glucose tolerance and increases sugar intake in the diurnal rodent <i>Arvicanthis ansorgei</i> in a sex‐dependent manner
Blue light at night acutely impairs glucose tolerance and increases sugar intake in the diurnal rodent <i>Arvicanthis ansorgei</i> in a sex‐dependent manner Open
In our modern society, the exposure to light at night (LAN) has increased considerably, which may impact human health negatively. Especially exposure to light at night containing short wavelength emissions (~450-500 nm) can disrupt the nor…
View article: Genetic variation analysis in a follow‐up study of gastric cancer precursor lesions confirms the association of <i>MUC2</i> variants with the evolution of the lesions and identifies a significant association with <i>NFKB1</i> and <i>CD14</i>
Genetic variation analysis in a follow‐up study of gastric cancer precursor lesions confirms the association of <i>MUC2</i> variants with the evolution of the lesions and identifies a significant association with <i>NFKB1</i> and <i>CD14</i> Open
Gastric carcinogenesis proceeds through a series of gastric cancer precursor lesions (GCPLs) leading to gastric cancer (GC) development. Although Helicobacter pylori infection initiates this process, genetic factors also play a role. We pr…
View article: Food-Anticipatory Behavior in Neonatal Rabbits and Rodents: An Update on the Role of Clock Genes
Food-Anticipatory Behavior in Neonatal Rabbits and Rodents: An Update on the Role of Clock Genes Open
In mammals, the suprachiasmatic nucleus (SCN), the master circadian clock, is mainly synchronized to the environmental light/dark cycle. SCN oscillations are maintained by a molecular clockwork in which certain genes, Period 1-2, Cry1-2, B…
View article: A Free-Choice High-Fat High-Sugar Diet Alters Day–Night Per2 Gene Expression in Reward-Related Brain Areas in Rats
A Free-Choice High-Fat High-Sugar Diet Alters Day–Night Per2 Gene Expression in Reward-Related Brain Areas in Rats Open
Under normal light-dark conditions, nocturnal rodents consume most of their food during the dark period. Diets high in fat and sugar, however, may affect the day-night feeding rhythm resulting in a higher light phase intake. In vitro and i…
View article: Environmental light and time of day modulate subjective liking and wanting.
Environmental light and time of day modulate subjective liking and wanting. Open
Several studies demonstrated effects of light on affect via projections from the retina of the eye to the circadian clock or via projections to areas involved in mood and reward. Few field studies investigated how naturally fluctuating lig…
Bright environmental light ameliorates deficient subjective ‘liking’ in insomnia: an experience sampling study Open
Wanting and Liking, rather than more commonly used mood adjectives, showed an increased sensitivity to detect deficient hedonic and reward processing in insomnia during everyday life. Deficient Liking may in part be rescued by exposure to …
View article: Brain Tissue Culture of Per2::Luciferase Transgenic Mice for ex vivo Bioluminescence
Brain Tissue Culture of Per2::Luciferase Transgenic Mice for ex vivo Bioluminescence Open
In circadian research, it is essential to be able to track a biological rhythm for several days with the minimum perturbation for the organisms or tissues. The use of transgenic mice lines, in which the luciferase reporter is coupled to a …
View article: Diet-Induced Obesity and Circadian Disruption of Feeding Behavior
Diet-Induced Obesity and Circadian Disruption of Feeding Behavior Open
Feeding behavior shows a rhythmic daily pattern, which in nocturnal rodents is observed mainly during the dark period. This rhythmicity is under the influence of the hypothalamic suprachiasmatic nucleus (SCN), the main biological clock. Ne…
View article: The electric vehicle routing problem with nonlinear charging function
The electric vehicle routing problem with nonlinear charging function Open
Electric vehicle routing problems (E-VRPs) extend classical routing problems to consider the limited driving range of electric vehicles. In general, this limitation is overcome by introducing planned detours to battery charging stations. M…
View article: Rev‐Erbα modulates retinal visual processing and behavioral responses to light
Rev‐Erbα modulates retinal visual processing and behavioral responses to light Open
The circadian clock is thought to adjust retinal sensitivity to ambient light levels, yet the involvement of specific clock genes is poorly understood. We explored the potential role of the nuclear receptor subfamily 1, group D, member 1 (…
View article: Insights into the Role of the Habenular Circadian Clock in Addiction
Insights into the Role of the Habenular Circadian Clock in Addiction Open
Drug addiction is a brain disease involving alterations in anatomy and functional neural communication. Drug intake and toxicity show daily rhythms in both humans and rodents. Evidence concerning the role of clock genes in drug intake has …