Nicole Gehring
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View article: Staff perspectives on the impacts of the COVID-19 pandemic on the provision of emergency department care for patients who use opioids
Staff perspectives on the impacts of the COVID-19 pandemic on the provision of emergency department care for patients who use opioids Open
The COVID-19 pandemic highlighted significant changes in ED care delivery for patients who use opioids. Efforts to enhance EDs should include anticipating the needs of people who use substances and the healthcare providers who care for the…
View article: Using dynamic extensions for the backstepping control of hyperbolic systems
Using dynamic extensions for the backstepping control of hyperbolic systems Open
This paper systematically introduces dynamic extensions for the boundary control of general heterodirectional hyperbolic PDE systems. These extensions, which are well known in the finite-dimensional setting, constitute the dynamics of stat…
View article: Patient preferences for breast cancer screening: a systematic review update to inform recommendations by the Canadian Task Force on Preventive Health Care
Patient preferences for breast cancer screening: a systematic review update to inform recommendations by the Canadian Task Force on Preventive Health Care Open
Background Different guideline panels, and individuals, may make different decisions based in part on their preferences. Preferences for or against an intervention are viewed as a consequence of the relative importance people place on the …
View article: Patient preferences for breast cancer screening: a systematic review update to inform recommendations by the Canadian Task Force on Preventive Health Care
Patient preferences for breast cancer screening: a systematic review update to inform recommendations by the Canadian Task Force on Preventive Health Care Open
Background Different guideline panels, and individuals, may make different decisions based in part by their preferences. This systematic review update examined the relative importance placed by patients aged ≥ 35 years on the potential out…
View article: Backstepping Design of Dynamic Observers for Hyperbolic Systems
Backstepping Design of Dynamic Observers for Hyperbolic Systems Open
View article: The B1 H+-ATPase (Atp6v1b1) Subunit in Non–Type A Intercalated Cells is Required for Driving Pendrin Activity and the Renal Defense Against Alkalosis
The B1 H+-ATPase (Atp6v1b1) Subunit in Non–Type A Intercalated Cells is Required for Driving Pendrin Activity and the Renal Defense Against Alkalosis Open
Significance Statement In the kidney, the B1 H + -ATPase subunit is mostly expressed in intercalated cells (IC). Its importance in acid-secreting type A ICs is evident in patients with inborn distal renal tubular acidosis and ATP6V1B1 muta…
View article: Control of distributed-parameter systems using normal forms: an introduction
Control of distributed-parameter systems using normal forms: an introduction Open
This paper gives an overview of the control of distributed-parameter systems using normal forms. Considering linear controllable PDE-ODE systems of hyperbolic type, two methods derive tracking controllers by mapping the system into a form …
View article: Backstepping Control of Coupled General Hyperbolic-Parabolic PDE-PDE Systems
Backstepping Control of Coupled General Hyperbolic-Parabolic PDE-PDE Systems Open
This paper considers the backstepping state feedback and observer design for hyperbolic and parabolic PDEs, which are bidirectionally interconnected in a general coupling structure. Both PDE subsystems consist of coupled scalar PDEs with t…
View article: Control of distributed-parameter systems using normal forms: An introduction
Control of distributed-parameter systems using normal forms: An introduction Open
This paper gives an overview of the control of distributed-parameter systems using normal forms. Considering linear controllable PDE-ODE systems of hyperbolic type, two methods derive tracking controllers by mapping the system into a form …
View article: Backstepping-based tracking control of the vertical gradient freeze crystal growth process
Backstepping-based tracking control of the vertical gradient freeze crystal growth process Open
The vertical gradient freeze crystal growth process is the main technique for the production of high quality compound semiconductors that are vital for today's electronic applications. A simplified model of this process consists of two 1D …
View article: Backstepping-based tracking control of the vertical gradient freeze crystal growth process
Backstepping-based tracking control of the vertical gradient freeze crystal growth process Open
The vertical gradient freeze crystal growth process is the main technique for the production of high quality compound semiconductors that are vital for today's electronic applications. A simplified model of this process consists of two 1D …
View article: <i>Resilin</i> is needed for wing posture in <i>Drosophila suzukii</i>
<i>Resilin</i> is needed for wing posture in <i>Drosophila suzukii</i> Open
Resilin is a protein matrix in movable regions of the cuticle conferring resistance to fatigue. The main component of Resilin is Pro‐Rresilin that polymerises via covalent di‐ and tri‐tyrosine bounds (DT). Loss of Pro‐Resilin is nonlethal …
View article: Chronic High Phosphate Intake in Mice Affects Macronutrient Utilization and Body Composition
Chronic High Phosphate Intake in Mice Affects Macronutrient Utilization and Body Composition Open
Scope In the last decades, dietary phosphate intake has increased due to a higher consumption of ultraprocessed food. This higher intake has an impact on body composition and health state. Recently, this study finds that a high chronic pho…
View article: Flatness-based analysis and control design for 2 × 2 hyperbolic PDEs with nonlinear boundary dynamics
Flatness-based analysis and control design for 2 × 2 hyperbolic PDEs with nonlinear boundary dynamics Open
Distributed-parameter systems represented by linear one-dimensional 2 × 2 hyperbolic PDEs with nonlinear finite-dimensional differentially flat dynamics at one boundary and control acting linearly via the opposite boundary are considered. …
View article: On the Calculation of Differential Parametrizations for the Feedforward Control of an Euler–Bernoulli Beam
On the Calculation of Differential Parametrizations for the Feedforward Control of an Euler–Bernoulli Beam Open
View article: Ratio between Lactobacillus plantarum and Acetobacter pomorum on the surface of Drosophila melanogaster adult flies depends on cuticle melanisation
Ratio between Lactobacillus plantarum and Acetobacter pomorum on the surface of Drosophila melanogaster adult flies depends on cuticle melanisation Open
View article: Correction to: Resilin matrix distribution, variability and function in Drosophila
Correction to: Resilin matrix distribution, variability and function in Drosophila Open
View article: Ratio Between Lactobacillus Plantarum and Acetobacter Pomorum on the Surface of Drosophila Melanogaster Adult Flies Depends on Cuticle Melanisation
Ratio Between Lactobacillus Plantarum and Acetobacter Pomorum on the Surface of Drosophila Melanogaster Adult Flies Depends on Cuticle Melanisation Open
Objectives As in most organisms, the surface of the fruit fly Drosophila melanogaster is associated with bacteria. In order to study the genetic parameters of this association, we developed a simple protocol for surface bacteria isolation …
View article: A chronic high phosphate intake in mice is detrimental for bone health without major renal alterations
A chronic high phosphate intake in mice is detrimental for bone health without major renal alterations Open
Background Phosphate intake has increased in the last decades due to a higher consumption of processed foods. This higher intake is detrimental for patients with chronic kidney disease, increasing mortality and cardiovascular disease risk …
View article: Systemic Jak1 activation provokes hepatic inflammation and imbalanced FGF23 production and cleavage
Systemic Jak1 activation provokes hepatic inflammation and imbalanced FGF23 production and cleavage Open
Fibroblast growth factor 23 (FGF23) is a main regulator of mineral homeostasis. Low and high circulating FGF23 levels are associated with bone, renal, cardiovascular diseases, and increased mortality. Understanding the factors and signalin…
View article: Supplementary Material for: Jak1/Stat3 Activation Alters Phosphate Metabolism Independently of Sex and Extracellular Phosphate Levels
Supplementary Material for: Jak1/Stat3 Activation Alters Phosphate Metabolism Independently of Sex and Extracellular Phosphate Levels Open
Introduction: Phosphate homeostasis is regulated by a complex network involving the parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), and calcitriol acting on several organs including the kidney, intestine, bone…
View article: A Systematic Design of Backstepping-Based State Feedback Controllers for ODE-PDE-ODE Systems
A Systematic Design of Backstepping-Based State Feedback Controllers for ODE-PDE-ODE Systems Open
The backstepping design of stabilizing state feedback controllers is addressed for bidirectionally coupled ODE-PDE-ODE systems, that naturally arise for infinite-dimensional systems where actuator or sensor dynamics are taken into account.…
View article: Trajectory Tracking Control for a Class of 2×2 Hyperbolic PDE-ODE Systems
Trajectory Tracking Control for a Class of 2×2 Hyperbolic PDE-ODE Systems Open
This paper introduces an approach to trajectory tracking control of linear 2×2 hyperbolic partial differential equations (PDEs) actuated at one boundary and coupled with ordinary differential equations (ODEs) at the other one. Well-known s…
View article: Jak1/Stat3 Activation Alters Phosphate Metabolism Independently of Sex and Extracellular Phosphate Levels
Jak1/Stat3 Activation Alters Phosphate Metabolism Independently of Sex and Extracellular Phosphate Levels Open
Introduction: Phosphate homeostasis is regulated by a complex network involving the parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), and calcitriol acting on several organs including the kidney, intestine, bone…
View article: Toxicity of Dithiothreitol (DTT) to Drosophila melanogaster
Toxicity of Dithiothreitol (DTT) to Drosophila melanogaster Open
View article: Resilin matrix distribution, variability and function in Drosophila
Resilin matrix distribution, variability and function in Drosophila Open
Background Elasticity prevents fatigue of tissues that are extensively and repeatedly deformed. Resilin is a resilient and elastic extracellular protein matrix in joints and hinges of insects. For its mechanical properties, Resilin is exte…
View article: Tweedle proteins form extracellular two-dimensional structures defining body and cell shape in <i>Drosophila melanogaster</i>
Tweedle proteins form extracellular two-dimensional structures defining body and cell shape in <i>Drosophila melanogaster</i> Open
Tissue function and shape rely on the organization of the extracellular matrix (ECM) produced by the respective cells. Our understanding of the underlying molecular mechanisms is limited. Here, we show that extracellular Tweedle (Twdl) pro…
View article: Output Feedback Control of Coupled Linear Parabolic ODE–PDE–ODE Systems
Output Feedback Control of Coupled Linear Parabolic ODE–PDE–ODE Systems Open
This paper deals with the backstepping design of observer-based compensators for parabolic ODE-PDE-ODE systems. The latter consist of n coupled parabolic PDEs with distinct diffusion coefficients and spatially-varying coefficients, that ar…
View article: Transcriptional Control of Quality Differences in the Lipid-Based Cuticle Barrier in Drosophila suzukii and Drosophila melanogaster
Transcriptional Control of Quality Differences in the Lipid-Based Cuticle Barrier in Drosophila suzukii and Drosophila melanogaster Open
Cuticle barrier efficiency in insects depends largely on cuticular lipids. To learn about the evolution of cuticle barrier function, we compared the basic properties of the cuticle inward and outward barrier function in adults of the fruit…
View article: Ein systematischer Backstepping-Zugang zur Regelung gekoppelter ODE-PDE-ODE-Systeme
Ein systematischer Backstepping-Zugang zur Regelung gekoppelter ODE-PDE-ODE-Systeme Open
Zusammenfassung Der systematische Zugang zum Backstepping-Entwurf von Zustandsrückführungen für gekoppelte ODE-PDE-ODE-Systeme, die sich zumeist für verteilt-parametrische Prozesse unter Berücksichtigung der Dynamik von Aktoren und Sensore…