Nicole E. Patterson
YOU?
Author Swipe
View article: Tracking poliovirus through wastewater: environmental surveillance insights from Haïti (2020–2023)
Tracking poliovirus through wastewater: environmental surveillance insights from Haïti (2020–2023) Open
Environmental surveillance (ES) for poliovirus is a critical component of global eradication efforts, enabling the detection of virus circulation in communities, even in the absence of acute flaccid paralysis (AFP) cases. To monitor poliov…
View article: Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups
Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups Open
Background The Cancer Genome Atlas identified four molecular subgroups of endometrial cancer with survival differences based on whole genome, transcriptomic, and proteomic characterization. Clinically accessible algorithms that reproduce t…
View article: Additional file 7 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups
Additional file 7 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups Open
Additional file 7. Table S7 - Insertion/deletion variants identified in each sample.
View article: Additional file 4 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups
Additional file 4 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups Open
Additional file 4. Table S4 - Somatic variants compared by tumor histology and grade.
View article: Additional file 5 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups
Additional file 5 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups Open
Additional file 5. Table S5 - Filtered somatic variants identified in each sample with annotative data.
View article: Additional file 1 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups
Additional file 1 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups Open
Additional file 1. Table S1 - Panel design for POLE sequencing.
View article: Additional file 6 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups
Additional file 6 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups Open
Additional file 6. Table S6 - PrDSM pathogenicity scores for synonymous variants.
View article: Additional file 2 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups
Additional file 2 of Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups Open
Additional file 2. Table S2 - Next generation sequencing data presented by sample.
View article: Correction: Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions
Correction: Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions Open
View article: Insertional oncogenesis by HPV70 revealed by multiple genomic analyses in a clinically HPV‐negative cervical cancer
Insertional oncogenesis by HPV70 revealed by multiple genomic analyses in a clinically HPV‐negative cervical cancer Open
Cervical carcinogenesis, the second leading cause of cancer death in women worldwide, is caused by multiple types of human papillomaviruses (HPVs). To investigate a possible role for HPV in a cervical carcinoma that was HPV‐negative by PCR…
View article: Insertional oncogenesis by HPV70 revealed by multiple genomic analyses in a clinically HPV-negative cervical cancer
Insertional oncogenesis by HPV70 revealed by multiple genomic analyses in a clinically HPV-negative cervical cancer Open
Cervical carcinogenesis, the second leading cause of cancer death in women worldwide, is caused by multiple types of human papillomaviruses (HPVs). To investigate a possible role for HPV in a cervical carcinoma that was HPV-negative by PCR…
View article: Development and validation of a targeted next generation DNA sequencing panel outperforming whole exome sequencing for the identification of clinically relevant genetic variants
Development and validation of a targeted next generation DNA sequencing panel outperforming whole exome sequencing for the identification of clinically relevant genetic variants Open
Next generation sequencing (NGS) technologies have revolutionized our approach to genomic research. The use of whole genome sequencing (WGS), whole exome sequencing (WES), transcriptome profiling, and targeted DNA sequencing has exponentia…
View article: Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus
Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus Open
View article: Technological advances in precision medicine and drug development
Technological advances in precision medicine and drug development Open
New technologies are rapidly becoming available to expand the arsenal of tools accessible for precision medicine and to support the development of new therapeutics. Advances in liquid biopsies, which analyze cells, DNA, RNA, proteins, or v…
View article: Additional file 3: Table S1. of Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus
Additional file 3: Table S1. of Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus Open
Lists of p values of principal component analysis with known covariates. Table S2. A list of differentially expressed genes. Table S3. Lists of differentially methylated HpaII sites in each model. Table S4. A list of differentially methyla…
View article: Additional file 8: of Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus
Additional file 8: of Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus Open
Supporting Tables. (XLSX 15.7 MB)
View article: Additional file 7: of Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus
Additional file 7: of Amnion as a surrogate tissue reporter of the effects of maternal preeclampsia on the fetus Open
Codes used in this study. (TXT 66.7 kb)
View article: Post-conversion targeted capture of modified cytosines in mammalian and plant genomes
Post-conversion targeted capture of modified cytosines in mammalian and plant genomes Open
We present a capture-based approach for bisulfiteconverted DNA that allows interrogation of predefined genomic locations, allowing quantitative and qualitative assessments of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) at CG …