Andrea Grant
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View article: Advancing whole‐brain <scp>BOLD functional MRI</scp> in humans at 10.5 T with motion‐robust <scp>3D echo‐planar imaging</scp> , parallel transmission, and high‐density <scp>radiofrequency</scp> receive coils
Advancing whole‐brain <span>BOLD functional MRI</span> in humans at 10.5 T with motion‐robust <span>3D echo‐planar imaging</span> , parallel transmission, and high‐density <span>radiofrequency</span> receive coils Open
Purpose To demonstrate the feasibility and performance of whole‐brain blood oxygen level–dependent functional MRI (fMRI) in humans at 10.5 T by combining motion‐robust three‐dimensional gradient‐echo echo‐planar imaging, parallel transmiss…
View article: Center-surround processing in psychosis
Center-surround processing in psychosis Open
Purpose People with psychotic psychopathology (PwPP) often experience subtle variations in visual perception, which can be quantified experimentally. In the contrast surround suppression illusion, a central pattern appears to have lower co…
View article: A Numerical Alternative to MR Thermometry for Safety Validation of Multi-Channel RF Transmit Coils
A Numerical Alternative to MR Thermometry for Safety Validation of Multi-Channel RF Transmit Coils Open
Purpose This study proposes an alternative approach to MR thermometry (MRT) for the safety validation of multi-channel RF transmit coils and demonstrates its use to enable human studies at 10.5T. Methods To ensure patient safety, specific …
View article: Mesoscopic whole-brain T<sub>2</sub>*-weighted and associated quantitative MRI in healthy humans at 10.5 T
Mesoscopic whole-brain T<sub>2</sub>*-weighted and associated quantitative MRI in healthy humans at 10.5 T Open
Purpose To demonstrate the feasibility and performance of mesoscopic whole brain T 2 *-weighted (T 2 *w) MRI at 10.5 T by combining a motion-robust multi-echo gradient-echo (GRE) method with high-density RF receive arrays. Methods Multi-ec…
View article: A 128‐channel receive array with enhanced signal‐to‐noise ratio performance for 10.5T brain imaging
A 128‐channel receive array with enhanced signal‐to‐noise ratio performance for 10.5T brain imaging Open
Purpose To develop and characterize a 128‐channel head array for brain imaging at 10.5 T, evaluate signal‐to‐noise ratio (SNR) relative to ultimate intrinsic SNR (uiSNR) and lower field strengths, and demonstrate human brain anatomical and…
View article: On the <scp>RF</scp> safety of titanium mesh head implants in <scp>7 T MRI</scp> systems: an investigation
On the <span>RF</span> safety of titanium mesh head implants in <span>7 T MRI</span> systems: an investigation Open
Purpose Patients undergoing craniofacial surgery for skull reconstruction may have titanium mesh implants. The safety risks related to 7 T MRI with these patients are not well understood. This study investigates the RF heating of titanium …
View article: Exploring in vivo human brain metabolism at 10.5 T: Initial insights from MR spectroscopic imaging
Exploring in vivo human brain metabolism at 10.5 T: Initial insights from MR spectroscopic imaging Open
These preliminary findings highlight the potential of 10.5 T MRSI as a powerful imaging tool for probing cerebral metabolism. By providing unprecedented spatial and spectral resolution, this technology could offer a unique view into the me…
View article: A 128-channel receive array with enhanced SNR performance for 10.5 tesla brain imaging
A 128-channel receive array with enhanced SNR performance for 10.5 tesla brain imaging Open
Purpose To develop and characterize the performance of a 128-channel head array for brain imaging at 10.5 tesla and evaluate the potential of brain imaging at this unique, >10 tesla magnetic field. Methods The coil is composed of a 16-chan…
View article: <scp>RF</scp> coil design strategies for improving <scp>SNR</scp> at the ultrahigh magnetic field of 10.5T
<span>RF</span> coil design strategies for improving <span>SNR</span> at the ultrahigh magnetic field of 10.5T Open
Purpose Toward pushing the boundaries of ultrahigh fields for human brain imaging, we wish to evaluate experimentally achievable SNR relative to ultimate intrinsic SNR (uiSNR) at 10.5T, develop design strategies toward approaching the latt…
View article: RF coil design strategies for improving SNR at the ultrahigh magnetic field of 10.5 Tesla
RF coil design strategies for improving SNR at the ultrahigh magnetic field of 10.5 Tesla Open
Purpose To develop multichannel transmit and receive arrays towards capturing the ultimate-intrinsic-SNR (uiSNR) at 10.5 Tesla (T) and to demonstrate the feasibility and potential of whole-brain, high-resolution human brain imaging at this…
View article: Faster bi-stable visual switching in psychosis
Faster bi-stable visual switching in psychosis Open
Bi-stable stimuli evoke two distinct perceptual interpretations that alternate and compete for dominance. Bi-stable perception is thought to be driven at least in part by mutual suppression between distinct neural populations that represen…
View article: Performance of receive head arrays versus ultimate intrinsic <scp>SNR</scp> at 7 T and 10.5 T
Performance of receive head arrays versus ultimate intrinsic <span>SNR</span> at 7 T and 10.5 T Open
Purpose We examined magnetic field dependent SNR gains and ability to capture them with multichannel receive arrays for human head imaging in going from 7 T, the most commonly used ultrahigh magnetic field (UHF) platform at the present, to…
View article: The effect of tobacco use on performance in a structure-from-motion task among patients with psychotic psychopathology.
The effect of tobacco use on performance in a structure-from-motion task among patients with psychotic psychopathology. Open
Psychotic disorders are debilitating, in part, due to psychotic symptoms, like hallucinations or delusions. Additionally, patients with psychotic psychopathology (PwPP) typically display reduced cognitive performance on visual-spatial work…
View article: Use of a Commercial 7-T MRI Scanner for Clinical Brain Imaging: Indications, Protocols, Challenges, and Solutions—A Single-Center Experience
Use of a Commercial 7-T MRI Scanner for Clinical Brain Imaging: Indications, Protocols, Challenges, and Solutions—A Single-Center Experience Open
The first commercially available 7-T MRI scanner (Magnetom Terra) was approved by the FDA in 2017 for clinical imaging of the brain and knee. After initial protocol development and sequence optimization efforts in volunteers, the 7-T syste…
View article: The psychosis human connectome project: Design and rationale for studies of visual neurophysiology
The psychosis human connectome project: Design and rationale for studies of visual neurophysiology Open
Visual perception is abnormal in psychotic disorders such as schizophrenia. In addition to hallucinations, laboratory tests show differences in fundamental visual processes including contrast sensitivity, center-surround interactions, and …
View article: Faster bi-stable visual switching in psychosis
Faster bi-stable visual switching in psychosis Open
Bi-stable stimuli evoke two distinct perceptual interpretations that alternate and compete for dominance. Bi-stable perception is thought to be driven at least in part by mutual suppression between distinct neural populations that represen…
View article: Investigating the relationship between blinks, saccades, and bistable percepts during a structure-from-motion task in patients with psychosis
Investigating the relationship between blinks, saccades, and bistable percepts during a structure-from-motion task in patients with psychosis Open
Bistable percepts are those in which the same physical stimulus causes two spontaneously alternating internal perceptual states. Individuals vary widely in their switch rate within and between different bistable tasks. An abrupt change in …
View article: Studies of visual neurophysiology in the psychosis Human Connectome Project
Studies of visual neurophysiology in the psychosis Human Connectome Project Open
People with psychosis spectrum disorders (e.g., schizophrenia) experience abnormal sensory percepts such as hallucinations and illusions (real stimuli are mis-perceived). Previous work has shown differences in visual task performance among…
View article: The Psychosis Human Connectome Project: Design and rationale for studies of visual neurophysiology
The Psychosis Human Connectome Project: Design and rationale for studies of visual neurophysiology Open
Visual perception is abnormal in psychotic disorders such as schizophrenia. In addition to hallucinations, laboratory tests show differences in fundamental visual processes including contrast sensitivity, center-surround interactions, and …
View article: Magnetic field strength dependent signal-to-noise ratio gain at the center of a spherical phantom and up to 11.7T
Magnetic field strength dependent signal-to-noise ratio gain at the center of a spherical phantom and up to 11.7T Open
Purpose: The SNR at the center of a spherical phantom of known electrical properties was measured in quasi-identical experimental conditions as a function of magnetic field strength between 3T and 11.7T. Methods: SNR was measured at the ce…
View article: Magnetic field strength dependent SNR gain at the center of a spherical phantom and up to 11.<scp>7T</scp>
Magnetic field strength dependent SNR gain at the center of a spherical phantom and up to 11.<span>7T</span> Open
Purpose The SNR at the center of a spherical phantom of known electrical properties was measured in quasi‐identical experimental conditions as a function of magnetic field strength between 3 T and 11.7 T. Methods The SNR was measured at th…
View article: Design of a Self Decoupled 16 Channel Transmitter for Human Brain MRI at 447MHz
Design of a Self Decoupled 16 Channel Transmitter for Human Brain MRI at 447MHz Open
Transmitter arrays play a critical role in ultra high field Magnetic Resonance Imaging (MRI), especially given the advantages made possible via parallel transmission (pTx) techniques. One of the challenges in design and construction of tra…
View article: Designing a Self-Decoupled 16 Channel Transmitter for Human Brain Magnetic Resonance Imaging at 447MHz
Designing a Self-Decoupled 16 Channel Transmitter for Human Brain Magnetic Resonance Imaging at 447MHz Open
Transmitter arrays play a critical role in ultra high field Magnetic Resonance Imaging (MRI), especially given the advantages made possible via parallel transmission (pTx) techniques. One of the challenges in design and construction of tra…
View article: An 8‐dipole transceive and 24‐loop receive array for non‐human primate head imaging at 10.5 T
An 8‐dipole transceive and 24‐loop receive array for non‐human primate head imaging at 10.5 T Open
A 32‐channel RF coil was developed for brain imaging of anesthetized non‐human primates (rhesus macaque) at 10.5 T. The coil is composed of an 8‐channel dipole transmit/receive array, close‐fitting 16‐channel loop receive array headcap, an…
View article: Comparison of 16-Channel Asymmetric Sleeve Antenna and Dipole Antenna Transceiver Arrays at 10.5 Tesla MRI
Comparison of 16-Channel Asymmetric Sleeve Antenna and Dipole Antenna Transceiver Arrays at 10.5 Tesla MRI Open
Multi-element transmit arrays with low peak 10 g specific absorption rate (SAR) and high SAR efficiency (defined as ( [Formula: see text]SAR [Formula: see text] are essential for ultra-high field (UHF) magnetic resonance imaging (MRI) appl…
View article: An 8 Dipole Transceive and 24 Loop Receive Array for Non-Human Primate Head Imaging at 10.5T
An 8 Dipole Transceive and 24 Loop Receive Array for Non-Human Primate Head Imaging at 10.5T Open
A 32-channel RF coil was developed for brain imaging of anesthetized non-human primates (Rhesus Macaque) at 10.5 tesla. The coil is composed of an 8-channel dipole transmit/receive array, close-fitting 16-channel loop receive array headcap…
View article: Introduction of the snake antenna array: Geometry optimization of a sinusoidal dipole antenna for 10.5T body imaging with lower peak SAR
Introduction of the snake antenna array: Geometry optimization of a sinusoidal dipole antenna for 10.5T body imaging with lower peak SAR Open
Purpose To improve imaging performance for body MRI with a local transmit array at 10.5T, the geometry of a dipole antenna was optimized to achieve lower peak specific absorption rate (SAR) levels and a more uniform transmit profile. Metho…