Nicole L. Spartano
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View article: Predictors of incident diabetes in two populations: framingham heart study and hispanic community health study / study of latinos
Predictors of incident diabetes in two populations: framingham heart study and hispanic community health study / study of latinos Open
View article: Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts
Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts Open
View article: Passive Measures of Physical Activity and Cadence as Early Indicators of Cognitive Impairment: Observational Study
Passive Measures of Physical Activity and Cadence as Early Indicators of Cognitive Impairment: Observational Study Open
Background Emerging research suggests that regular physical activity can reduce the risk of cognitive decline. However, most prior studies rely on self-reported measures, which are subject to recall bias, subjectivity, and limited temporal…
View article: Associations of diet composition and quality with continuous glucose monitor-derived glycemic metrics in a community-based cohort
Associations of diet composition and quality with continuous glucose monitor-derived glycemic metrics in a community-based cohort Open
Our findings demonstrate that carbohydrate intake and quality, in addition to overall diet quality, are associated with dynamic fluctuations in glucose concentrations. Future prospective analysis should examine whether glycemic variability…
View article: Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis
Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis Open
BACKGROUND: Taking fewer than the widely promoted "10 000 steps per day" has recently been associated with lower risk of all-cause mortality. The relationship of steps and cardiovascular disease (CVD) risk remains poorly described. A meta-…
View article: Blood Pressure Responses During Exercise Were Associated With Average Home Blood Pressure and Home Blood Pressure Variability: The Electronic Framingham Heart Study
Blood Pressure Responses During Exercise Were Associated With Average Home Blood Pressure and Home Blood Pressure Variability: The Electronic Framingham Heart Study Open
Background Abnormal exercise blood pressure (BP) responses are associated with hypertension and cardiovascular disease, but their relationship with home BP over a mid‐ to long‐term time span is unknown. Methods At an FHS (Framingham Heart …
View article: How Do Occupational Sedentary Behavior and Occupational Cognitive Complexity Relate to Cognitive Function? A Cross‐Sectional Study
How Do Occupational Sedentary Behavior and Occupational Cognitive Complexity Relate to Cognitive Function? A Cross‐Sectional Study Open
Background and Aims Lower occupational cognitive complexity (OCC) and physical inactivity have been associated with advanced brain aging and cognitive decline in older adulthood. We examined whether the association of occupational sedentar…
View article: Evaluating Acceptability and Utilization of an AI-Assisted Dietary Assessment Tool in Middle-Aged Adults
Evaluating Acceptability and Utilization of an AI-Assisted Dietary Assessment Tool in Middle-Aged Adults Open
View article: The Role of Gut Microbial Diversity in the Protective Association Between Plant-Based Diets and Metabolic Syndrome Risk
The Role of Gut Microbial Diversity in the Protective Association Between Plant-Based Diets and Metabolic Syndrome Risk Open
View article: Physical Activity, Cardiovascular Status, Mortality, and Prediabetes in Hispanic and Non-Hispanic Adults
Physical Activity, Cardiovascular Status, Mortality, and Prediabetes in Hispanic and Non-Hispanic Adults Open
Importance: Data are limited on the association of physical activity (PA) with incident cardiovascular disease (CVD) and mortality in prediabetes, especially in racial and ethnic minority groups, including Hispanic and Latino populations. …
View article: Passive Measures of Physical Activity and Cadence as Early Indicators of Cognitive Impairment (Preprint)
Passive Measures of Physical Activity and Cadence as Early Indicators of Cognitive Impairment (Preprint) Open
BACKGROUND Emerging research shows regular physical activity reduces cognitive decline risk, but most studies rely on self-reported measures, which are limited by recall bias, subjectivity, and a lack of continuous monitoring capability. …
View article: Expert Clinical Interpretation of Continuous Glucose Monitor Reports From Individuals Without Diabetes
Expert Clinical Interpretation of Continuous Glucose Monitor Reports From Individuals Without Diabetes Open
Background: Clinical interpretation of continuous glucose monitoring (CGM) data for people without diabetes has not been well established. This study aimed to investigate concordance among CGM experts in recommending clinical follow-up for…
View article: ASSOCIATIONS OF PHYSICAL ACTIVITY ENGAGEMENT WITH CEREBRAL AB AND TAU PET FROM MIDLIFE
ASSOCIATIONS OF PHYSICAL ACTIVITY ENGAGEMENT WITH CEREBRAL AB AND TAU PET FROM MIDLIFE Open
Higher midlife physical activity engagement has been associated with lower dementia risk in late life. However, the underlying mechanisms contributing to the protective effect remain unclear. The goal of the current study was to evaluate t…
View article: ASSOCIATIONS OF PHYSICAL ACTIVITY ENGAGEMENT WITH CEREBRAL AB AND TAU PET FROM MIDLIFE
ASSOCIATIONS OF PHYSICAL ACTIVITY ENGAGEMENT WITH CEREBRAL AB AND TAU PET FROM MIDLIFE Open
Higher midlife physical activity engagement has been associated with lower dementia risk in late life. However, the underlying mechanisms contributing to the protective effect remain unclear. The goal of the current study was to evaluate t…
View article: The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors.
The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors. Open
INTRODUCTION: An error grid compares measured versus reference glucose concentrations to assign clinical risk values to observed errors. Widely used error grids for blood glucose monitors (BGMs) have limited value because they do not also …
View article: The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors
The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors Open
Introduction: An error grid compares measured versus reference glucose concentrations to assign clinical risk values to observed errors. Widely used error grids for blood glucose monitors (BGMs) have limited value because they do not also …
View article: Defining Continuous Glucose Monitor Time in Range in a Large, Community-Based Cohort Without Diabetes
Defining Continuous Glucose Monitor Time in Range in a Large, Community-Based Cohort Without Diabetes Open
Context Continuous glucose monitor (CGM) companies are beginning to market these sensors to populations without diabetes, but the range of CGM values clinicians should expect to see for this population is unclear because there have been no…
View article: Associations of Physical Activity Engagement with Cerebral Amyloid-β and Tau from Midlife
Associations of Physical Activity Engagement with Cerebral Amyloid-β and Tau from Midlife Open
Background: Higher midlife physical activity engagement has been associated with lower dementia risk in late life. However, the underlying mechanisms contributing to the protective effect remain unclear. Objective: The goal of the current …
View article: Impact of Diet Composition and Quality on Continuous Glucose Monitor-Derived Measures of Glycemic Variability in Free-Living Adults
Impact of Diet Composition and Quality on Continuous Glucose Monitor-Derived Measures of Glycemic Variability in Free-Living Adults Open
View article: Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study
Association of Smartwatch-Based Heart Rate and Physical Activity With Cardiorespiratory Fitness Measures in the Community: Cohort Study Open
Background Resting heart rate (HR) and routine physical activity are associated with cardiorespiratory fitness levels. Commercial smartwatches permit remote HR monitoring and step count recording in real-world settings over long periods of…
View article: Physical Activity, Cardiovascular Status, Mortality, and Prediabetes in Hispanic and Non-Hispanic Adults
Physical Activity, Cardiovascular Status, Mortality, and Prediabetes in Hispanic and Non-Hispanic Adults Open
Importance Data are limited on the association of physical activity (PA) with incident cardiovascular disease (CVD) and mortality in prediabetes, especially in racial and ethnic minority groups, including Hispanic and Latino populations. O…
View article: Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study
Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study Open
Background Step counting is comparable among many research-grade and consumer-grade accelerometers in laboratory settings. Objective The purpose of this study was to compare the agreement between Actical and Apple Watch step-counting in a …
View article: Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study (Preprint)
Agreement Between Apple Watch and Actical Step Counts in a Community Setting: Cross-Sectional Investigation From the Framingham Heart Study (Preprint) Open
BACKGROUND Step counting is comparable among many research-grade and consumer-grade accelerometers in laboratory settings. OBJECTIVE The purpose of this study was to compare the agreement between Actical and Apple Watch step-counting in…
View article: Characterizing longitudinal change in accelerometry-based moderate-to-vigorous physical activity in the Hispanic Community Health Study/Study of Latinos and the Framingham Heart Study
Characterizing longitudinal change in accelerometry-based moderate-to-vigorous physical activity in the Hispanic Community Health Study/Study of Latinos and the Framingham Heart Study Open
Background Physical activity promotes health and is particularly important during middle and older age for decreasing morbidity and mortality. We assessed the correlates of changes over time in moderate-to-vigorous physical activity (MVPA)…
View article: Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors
Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors Open
Introduction: Cardiometabolic risk factors and epigenetic patterns, increased in physically inactive individuals, are associated with an accelerated brain aging process. Objective: To determine whether cardiometabolic risk factors and epig…
View article: Physical Activity Over the Lifecourse and Cardiovascular Disease
Physical Activity Over the Lifecourse and Cardiovascular Disease Open
Despite improvements in cardiovascular care in recent decades, cardiovascular disease (CVD) remains a leading cause of death worldwide. At its core, CVD is a largely preventable disease with diligent risk factor management and early detect…
View article: Association of Depressive Symptom Trajectory With Physical Activity Collected by mHealth Devices in the Electronic Framingham Heart Study: Cohort Study
Association of Depressive Symptom Trajectory With Physical Activity Collected by mHealth Devices in the Electronic Framingham Heart Study: Cohort Study Open
Background Few studies have examined the association between depressive symptom trajectories and physical activity collected by mobile health (mHealth) devices. Objective We aimed to investigate if antecedent depressive symptom trajectorie…
View article: Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis
Step Count, Self-reported Physical Activity, and Predicted 5-Year Risk of Atrial Fibrillation: Cross-sectional Analysis Open
Background Physical inactivity is a known risk factor for atrial fibrillation (AF). Wearable devices, such as smartwatches, present an opportunity to investigate the relation between daily step count and AF risk. Objective The objective of…
View article: Increasing Engagement in the Electronic Framingham Heart Study: Factorial Randomized Controlled Trial
Increasing Engagement in the Electronic Framingham Heart Study: Factorial Randomized Controlled Trial Open
Background Smartphone apps and mobile health devices offer innovative ways to collect longitudinal cardiovascular data. Randomized evidence regarding effective strategies to maintain longitudinal engagement is limited. Objective This study…
View article: Additional file 1 of Characterizing longitudinal change in accelerometry-based moderate-to-vigorous physical activity in the Hispanic Community Health Study/Study of Latinos and the Framingham Heart Study
Additional file 1 of Characterizing longitudinal change in accelerometry-based moderate-to-vigorous physical activity in the Hispanic Community Health Study/Study of Latinos and the Framingham Heart Study Open
Additional file 1.