Nicole M. Baker
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View article: Optic atrophy 1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1
Optic atrophy 1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1 Open
View article: Supplementary Table S1 from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Supplementary Table S1 from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer Open
Structure factors and crystal information
View article: Supplementary Data S1-S7 from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Supplementary Data S1-S7 from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer Open
All supplemental data with figure legends
View article: Supplementary Table S1 from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Supplementary Table S1 from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer Open
Structure factors and crystal information
View article: Supplementary Data S1-S7 from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Supplementary Data S1-S7 from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer Open
All supplemental data with figure legends
View article: Data from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Data from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer Open
Allele-specific signaling by different KRAS alleles remains poorly understood. The KRASG12R mutation displays uneven prevalence among cancers that harbor the highest occurrence of KRAS mutations: It is rare (∼1%) i…
View article: Data from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Data from Atypical KRAS<sup>G12R</sup> Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer Open
Allele-specific signaling by different KRAS alleles remains poorly understood. The KRASG12R mutation displays uneven prevalence among cancers that harbor the highest occurrence of KRAS mutations: It is rare (∼1%) i…
View article: Supplementary Figures from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Supplementary Figures from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers Open
Supplementary Figures S1-S4 Supplementary Figure S1 Western blots showing knockdown of ArhGAP11A or RacGAP1. Supplementary Figure S2 ArhGAP11A and RacGAP1 are both required for proliferation of HER2-enriched and luminal B breast cancer cel…
View article: Supplementary Figure Legends from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Supplementary Figure Legends from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers Open
Figure Legends for Supplementary Figures S1-S4
View article: Supplementary Figures from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Supplementary Figures from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers Open
Supplementary Figures S1-S4 Supplementary Figure S1 Western blots showing knockdown of ArhGAP11A or RacGAP1. Supplementary Figure S2 ArhGAP11A and RacGAP1 are both required for proliferation of HER2-enriched and luminal B breast cancer cel…
View article: Data from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Data from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers Open
The basal-like breast cancer (BLBC) subtype accounts for a disproportionately high percentage of overall breast cancer mortality. The current therapeutic options for BLBC need improvement; hence, elucidating signaling pathways that drive B…
View article: Data from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Data from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers Open
The basal-like breast cancer (BLBC) subtype accounts for a disproportionately high percentage of overall breast cancer mortality. The current therapeutic options for BLBC need improvement; hence, elucidating signaling pathways that drive B…
View article: Supplementary Figure Legends from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Supplementary Figure Legends from Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers Open
Figure Legends for Supplementary Figures S1-S4
View article: Evaluating mitochondrial length, volume, and cristae ultrastructure in rare mouse adult stem cell populations
Evaluating mitochondrial length, volume, and cristae ultrastructure in rare mouse adult stem cell populations Open
Since changes in mitochondrial morphology regulate key functions of stem cells, it is important to assess their structure under physiological and pathophysiological conditions. Here, we present techniques optimized in rare adult muscle ste…
View article: Implementation of a Standardized Premedication Bundle to Improve Procedure Success for Nonemergent Neonatal Intubations
Implementation of a Standardized Premedication Bundle to Improve Procedure Success for Nonemergent Neonatal Intubations Open
Introduction: The American Academy of Pediatrics recommends premedication for all nonemergent neonatal intubations, yet there remains significant variation in this practice nationally. We aimed to standardize our unit’s premedication pract…
View article: Tractor beam acoustic levitation for time resolved crystallography experiments
Tractor beam acoustic levitation for time resolved crystallography experiments Open
Proof of concept of serial crystallography is carried out through the translation of samples delivered by tractor beam levitation. This is achieved using arrays of low powered transducers, focused to produce acoustic traps. Contrary to tra…
View article: On diabetic foot ulcer knowledge gaps, innovation, evaluation, prediction markers, and clinical needs
On diabetic foot ulcer knowledge gaps, innovation, evaluation, prediction markers, and clinical needs Open
View article: The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells
The mitochondrial protein OPA1 regulates the quiescent state of adult muscle stem cells Open
View article: Muscle Stem Cell Fate is Directed by the Mitochondrial Fusion Protein OPA1
Muscle Stem Cell Fate is Directed by the Mitochondrial Fusion Protein OPA1 Open
During aging there is a decline in (MuSCs) and muscle regeneration, though the underlying reason is unknown. Interestingly, mitochondrial fragmentation is a common feature in aging, however, how this impacts MuSC function and maintenance h…
View article: 2021 Acknowledgments
2021 Acknowledgments Open
View article: Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer Open
Allele-specific signaling by different KRAS alleles remains poorly understood. The KRASG12R mutation displays uneven prevalence among cancers that harbor the highest occurrence of KRAS mutations: It is rare (∼1%) in lung and colorectal can…
View article: Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer Open
Allele-specific signaling by different KRAS alleles remains poorly understood. The KRASG12R mutation displays uneven prevalence among cancers that harbor the highest occurrence of KRAS mutations: It is rare (∼1%) in lung and colorectal can…
View article: Ultrastructure of Human Pancreatic Cancer Cells Treated with a TBK1 Inhibitor
Ultrastructure of Human Pancreatic Cancer Cells Treated with a TBK1 Inhibitor Open
Journal Article Ultrastructure of Human Pancreatic Cancer Cells Treated with a TBK1 Inhibitor Get access Linda Yasui, Linda Yasui Northern Illinois University, Department of Biological Sciences, DeKalb, IL, USA Corresponding author: lyasui…
View article: Evaluating the therapeutic potential of the PAK1 and TBK1 kinases in pancreatic ductal adenocarcinoma
Evaluating the therapeutic potential of the PAK1 and TBK1 kinases in pancreatic ductal adenocarcinoma Open
Pancreatic ductal adenocarcinoma (PDAC) is an extremely lethal cancer characterized by a high frequency (>95%) of activating mutations in the KRAS oncogene, which is a well-validated driver of PDAC growth. However, to date, no successful a…
View article: Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers Open
The basal-like breast cancer (BLBC) subtype accounts for a disproportionately high percentage of overall breast cancer mortality. The current therapeutic options for BLBC need improvement; hence, elucidating signaling pathways that drive B…
View article: Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers
Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers Open
The basal-like breast cancer (BLBC) subtype accounts for a disproportionately high percentage of overall breast cancer mortality. The current therapeutic options for BLBC need improvement; hence, elucidating signaling pathways that drive B…
View article: CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer
CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer Open
View article: CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer
CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer Open
Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with generally poor prognosis and no available targeted therapies, highlighting a critical unmet need to identify and characterize novel therapeutic targets. We pr…