Nicole Söll
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View article: Intrawound vancomycin powder for prevention of surgical site infections after open instrumented posterior spinal fusion (VANCO Trial)—methodology of a randomized, controlled, multicenter study
Intrawound vancomycin powder for prevention of surgical site infections after open instrumented posterior spinal fusion (VANCO Trial)—methodology of a randomized, controlled, multicenter study Open
ClinicalTrials.gov NCT04017468.
View article: Reconsideration of the resection strategy of eloquent brain metastasis in the era of postoperative stereotactic radiotherapy: a comparative analysis with non-eloquent metastasis
Reconsideration of the resection strategy of eloquent brain metastasis in the era of postoperative stereotactic radiotherapy: a comparative analysis with non-eloquent metastasis Open
Purpose To decrease the recurrence rate after complete resection of a brain metastasis, removal of a surgical safety margin is advocated. This is not always feasible when resecting a metastasis in an eloquent location. We aimed to assess t…
View article: Reconsideration of the surgical safety margin around brain metastasis in the era of postoperative stereotactic radiosurgery
Reconsideration of the surgical safety margin around brain metastasis in the era of postoperative stereotactic radiosurgery Open
View article: Natural history and growth characteristics of intracranial meningiomas: a serial volumetric analysis of 240 tumors
Natural history and growth characteristics of intracranial meningiomas: a serial volumetric analysis of 240 tumors Open
View article: P18.10.B Natural history of meningiomas - a serial volumetric analysis of 240 tumors
P18.10.B Natural history of meningiomas - a serial volumetric analysis of 240 tumors Open
Background The management of asymptomatic intracranial meningiomas is controversial. Through the assessment of growth predictors, we aimed to create the basis for practicable clinical pathways for the management of these tumors. Material a…
View article: P11.60.A Quantitative analysis of the MGMT methylation status of glioblastomas in the light of the 2021 WHO classification
P11.60.A Quantitative analysis of the MGMT methylation status of glioblastomas in the light of the 2021 WHO classification Open
Background Glioblastomas with methylation of the promotor region of the O(6)-methylguanine-DNA methyltransferase (MGMT) gene exhibit increased sensitivity to alkylating chemotherapy. Quantitative assessment of the MGMT promotor methylation…
View article: Quantitative Analysis of the MGMT Methylation Status of Glioblastomas in Light of the 2021 WHO Classification
Quantitative Analysis of the MGMT Methylation Status of Glioblastomas in Light of the 2021 WHO Classification Open
Background: Glioblastomas with methylation of the promoter region of the O(6)-methylguanine-DNA methyltransferase (MGMT) gene exhibit increased sensitivity to alkylating chemotherapy. Quantitative assessment of the MGMT promoter methylatio…
View article: Development and early diagnosis of critical illness myopathy in COVID‐19 associated acute respiratory distress syndrome
Development and early diagnosis of critical illness myopathy in COVID‐19 associated acute respiratory distress syndrome Open
Background The COVID‐19 pandemic has greatly increased the incidence and clinical importance of critical illness myopathy (CIM), because it is one of the most common complications of modern intensive care medicine. Current diagnostic crite…
View article: Tolerability of COVID-19 mRNA vaccines in patients with postural tachycardia syndrome: a cross-sectional study
Tolerability of COVID-19 mRNA vaccines in patients with postural tachycardia syndrome: a cross-sectional study Open
Background: Postural tachycardia syndrome (POTS) is a form of autonomic dysregulation. There is increasing evidence that the etiology may be immune-mediated in a subgroup of patients. Patients with POTS often experience an exacerbation of …
View article: Inhaled Nitric Oxide Treatment for Aneurysmal SAH Patients With Delayed Cerebral Ischemia
Inhaled Nitric Oxide Treatment for Aneurysmal SAH Patients With Delayed Cerebral Ischemia Open
Background We demonstrated experimentally that inhaled nitric oxide (iNO) dilates hypoperfused arterioles, increases tissue perfusion, and improves neurological outcome following subarachnoid hemorrhage (SAH) in mice. We performed a prospe…
View article: Anesthesia modality does not affect clinical outcomes of intra-arterial vasodilator treatment in patients with symptomatic cerebral vasospasms
Anesthesia modality does not affect clinical outcomes of intra-arterial vasodilator treatment in patients with symptomatic cerebral vasospasms Open
Background: Delayed cerebral ischemia and cerebral vasospasm remain the leading causes of poor outcome in survivors of aneurysmal subarachnoid hemorrhage. Refractory cerebral vasospasms can be treated with endovascular vasodilator therapy,…
View article: Anesthesia modality does not affect clinical outcomes of intra-arterial vasodilator treatment in patients with symptomatic cerebral vasospasms
Anesthesia modality does not affect clinical outcomes of intra-arterial vasodilator treatment in patients with symptomatic cerebral vasospasms Open
Background: Delayed cerebral ischemia and cerebral vasospasm remain the leading causes of poor outcome in survivors of aneurysmal subarachnoid hemorrhage. Refractory cerebral vasospasms can be treated with endovascular vasodilator therapy,…
View article: Individualized Brain Tissue Oxygen-Monitoring Probe Placement Helps to Guide Therapy and Optimizes Outcome in Neurocritical Care
Individualized Brain Tissue Oxygen-Monitoring Probe Placement Helps to Guide Therapy and Optimizes Outcome in Neurocritical Care Open
Background/Objective In order to monitor tissue oxygenation in patients with acute neurological disorders, probes for measurement of brain tissue oxygen tension (ptO 2 ) are often placed non-specifically in a right frontal lobe location. T…
View article: Nimodipine-Induced Blood Pressure Changes Can Predict Delayed Cerebral Ischemia
Nimodipine-Induced Blood Pressure Changes Can Predict Delayed Cerebral Ischemia Open
Background: Early diagnosis of delayed cerebral ischemia (DCI) in patients after aneurysmal subarachnoid hemorrhage (aSAH) still poses a leading problem in neurointensive care. The aim of this study was to analyze the effect of oral…
View article: Repetitive Computed Tomography Perfusion for Detection of Cerebral Vasospasm–Related Hypoperfusion in Aneurysmal Subarachnoid Hemorrhage
Repetitive Computed Tomography Perfusion for Detection of Cerebral Vasospasm–Related Hypoperfusion in Aneurysmal Subarachnoid Hemorrhage Open
View article: Preliminary Results of Emergency Computed Tomography–Guided Ventricular Drain Placement—Precision for the Most Difficult Cases
Preliminary Results of Emergency Computed Tomography–Guided Ventricular Drain Placement—Precision for the Most Difficult Cases Open
View article: No Routine Postoperative Head CT following Elective Craniotomy – A Paradigm Shift?
No Routine Postoperative Head CT following Elective Craniotomy – A Paradigm Shift? Open
ClinicalTrials.gov NCT01987648.