Antonio Ferretti
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View article: Machine learning models of Alzheimer's disease spectrum using blood tests
Machine learning models of Alzheimer's disease spectrum using blood tests Open
INTRODUCTION The diagnosis of Alzheimer's disease (AD) traditionally relies on cerebrospinal fluid and plasma levels of amyloid beta and phosphorylated tau. Although informative, these biomarkers represent a narrow, hypothesis‐driven appro…
View article: Performance Analysis of Innovative Propulsion Systems for Short-Haul Ferries
Performance Analysis of Innovative Propulsion Systems for Short-Haul Ferries Open
Antipollution regulations for marine applications have become increasingly stringent in recent years, with the International Maritime Organization (IMO) setting ambitious limitations for the coming years: a 70–80% reduction in greenhouse g…
View article: Atrophy of hippocampal subfields and amygdala nuclei in subjects with mild cognitive impairment progressing to Alzheimer's disease
Atrophy of hippocampal subfields and amygdala nuclei in subjects with mild cognitive impairment progressing to Alzheimer's disease Open
The hippocampus and amygdala are the first brain regions to show early signs of Alzheimer's Disease (AD) pathology. AD is preceded by a prodromal stage known as Mild Cognitive Impairment (MCI), a crucial crossroad in the clinical progressi…
View article: “Back to Braak”: Role of Nucleus Reuniens and Subcortical Pathways in Alzheimer's Disease Progression
“Back to Braak”: Role of Nucleus Reuniens and Subcortical Pathways in Alzheimer's Disease Progression Open
In line with the pathophysiological relevance of the nucleus reuniens proposed by seminal post-mortem studies on patients with AD, we confirm the pivotal role of this nucleus as a critical hub in the clinical progression to AD. We also pro…
View article: BOLD cardiorespiratory pulsatility in the brain: from noise to signal of interest
BOLD cardiorespiratory pulsatility in the brain: from noise to signal of interest Open
Functional magnetic resonance imaging (fMRI) based on the Blood Oxygen Level Dependent (BOLD) contrast has been extensively used to map brain activity and connectivity in health and disease. Standard fMRI preprocessing includes different s…
View article: Data-driven analysis of whole-brain intrinsic connectivity in patients with chronic low back pain undergoing osteopathic manipulative treatment
Data-driven analysis of whole-brain intrinsic connectivity in patients with chronic low back pain undergoing osteopathic manipulative treatment Open
This study offers insights into the brain mechanisms underlying the analgesic effect of OMT. Our findings support a link between OMT-driven functional cortical architecture alterations and improved clinical outcomes.
View article: LSD-induced changes in the functional connectivity of distinct thalamic nuclei
LSD-induced changes in the functional connectivity of distinct thalamic nuclei Open
The role of the thalamus in mediating the effects of lysergic acid diethylamide (LSD) was recently proposed in a model of communication and corroborated by imaging studies. However, a detailed analysis of LSD effects on nuclei-resolved tha…
View article: Atrophy of specific amygdala subfields in subjects converting to mild cognitive impairment
Atrophy of specific amygdala subfields in subjects converting to mild cognitive impairment Open
Introduction Accumulating evidence indicates that the amygdala exhibits early signs of Alzheimer's disease (AD) pathology. However, it is still unknown whether the atrophy of distinct subfields of the amygdala also participates in the tran…
View article: Effects of four-month-long foreign language learning on executive functions and white matter integrity in older adults
Effects of four-month-long foreign language learning on executive functions and white matter integrity in older adults Open
Objective Bilingualism has been associated with cognitive benefits and a potential protective effect against neurodegenerative conditions. Previous research has shown that bilingual individuals exhibit greater white matter integrity compar…
View article: Cerebral blood flow patterns in preterm and term neonates assessed with <scp>pseudo‐continuous</scp> arterial spin labeling perfusion <scp>MRI</scp>
Cerebral blood flow patterns in preterm and term neonates assessed with <span>pseudo‐continuous</span> arterial spin labeling perfusion <span>MRI</span> Open
In preterm (PT) infants, regional cerebral blood flow (CBF) disturbances may predispose to abnormal brain maturation even without overt brain injury. Therefore, it would be informative to determine the spatial distribution of grey matter (…
View article: Influence of tectonic deformation on the mechanical properties of calcareous rocks: drawbacks of the non-destructive techniques
Influence of tectonic deformation on the mechanical properties of calcareous rocks: drawbacks of the non-destructive techniques Open
Discontinuity surfaces are well known to influence the mechanical behaviour of rocks under compression. Non-destructive techniques, such as ultrasonic pulse velocity and sclerometers, are increasingly used to estimate uniaxial compressive …
View article: Altered Medial Prefrontal Connectivity in Parkinson's Disease Patients with Somatic Symptoms
Altered Medial Prefrontal Connectivity in Parkinson's Disease Patients with Somatic Symptoms Open
Background The high co‐occurrence of somatic symptom disorder (SSD) in Parkinson's disease (PD) patients suggests overlapping pathophysiology. However, little is known about the neural correlates of SSD and their possible interactions with…
View article: A Dedicated Tool for Presurgical Mapping of Brain Tumors and Mixed-Reality Navigation During Neurosurgery
A Dedicated Tool for Presurgical Mapping of Brain Tumors and Mixed-Reality Navigation During Neurosurgery Open
Brain tumor surgery requires a delicate tradeoff between complete removal of neoplastic tissue while minimizing loss of brain function. Functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) have emerged as valuabl…
View article: Clinical and Functional Comparison between Anatomical and Non-Anatomical Acute Repair of Tears of the Distal Tendon of Biceps Brachii
Clinical and Functional Comparison between Anatomical and Non-Anatomical Acute Repair of Tears of the Distal Tendon of Biceps Brachii Open
Aim.The aim of this study was to investigate whether the anatomical reconstruction on the radial tuberosity could be superior to the non-anatomical repair by tenodesis on brachialis, in terms of clinical outcomes and isokinetic evaluation …
View article: Amygdalar nuclei and hippocampal subfields on MRI: Test‐retest reliability of automated segmentation in old and young healthy volunteers
Amygdalar nuclei and hippocampal subfields on MRI: Test‐retest reliability of automated segmentation in old and young healthy volunteers Open
Background The amygdala and the hippocampus are two limbic structures that play a critical role in cognition and behaviour but their small size hampers their manual segmentation in multicenter datasets. Here, we assessed the reliability of…
View article: From the Core to the Border of Locally Advanced Rectal Cancer: A Novel MRI-based Clinical-Radiomic Model Early Predicts Treatment Response
From the Core to the Border of Locally Advanced Rectal Cancer: A Novel MRI-based Clinical-Radiomic Model Early Predicts Treatment Response Open
Neoadjuvant chemo-radiotherapy (CRT) followed by total mesorectal excision (TME) represents the standard treatment for patients with locally advanced (³ T3 or N+) rectal cancer (LARC). Approximately 15% of patients with LARC shows a comple…
View article: High <scp>γ‐Aminobutyric</scp> Acid Content Within the Medial Prefrontal Cortex Is a Functional Signature of Somatic Symptoms Disorder in Patients With Parkinson's Disease
High <span>γ‐Aminobutyric</span> Acid Content Within the Medial Prefrontal Cortex Is a Functional Signature of Somatic Symptoms Disorder in Patients With Parkinson's Disease Open
Background The dysfunctional activity of the medial prefrontal cortex has been associated with the appearance of the somatic symptom disorder, a key feature of the Parkinson's disease (PD) psychosis complex. Objectives The objectives of th…