Nigel McArdle
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View article: P080 The effect of long-term CPAP use on sub-clinical echocardiographic markers of cardiovascular disease in patients with moderate–severe OSA
P080 The effect of long-term CPAP use on sub-clinical echocardiographic markers of cardiovascular disease in patients with moderate–severe OSA Open
Background Obstructive sleep apnoea (OSA) has been associated with major adverse cardiac events (MACE) in longitudinal observational studies, however randomised controlled trials (RCTs) have not shown reduction in long-term risk of MACE wi…
View article: Corrigendum to “Additive interactions of sleep disorders, insufficient sleep, and shift work on road and workplace safety incidents: A sufficient cause approach with overlap weights” [Sleep Med 134 (2025) 106699]
Corrigendum to “Additive interactions of sleep disorders, insufficient sleep, and shift work on road and workplace safety incidents: A sufficient cause approach with overlap weights” [Sleep Med 134 (2025) 106699] Open
View article: Additive interactions of sleep disorders, insufficient sleep, and shift work on road and workplace safety incidents: A sufficient cause approach with overlap weights
Additive interactions of sleep disorders, insufficient sleep, and shift work on road and workplace safety incidents: A sufficient cause approach with overlap weights Open
The combined burden of multiple sleep-disrupting factors including sleep disorders, insufficient sleep and shift work, is associated with an increased risk of near-miss road incidents and falling asleep at work. Given that sleepiness, both…
View article: 0674 Short-Term Reliability of Obstructive Sleep Apnea Symptom Subtypes
0674 Short-Term Reliability of Obstructive Sleep Apnea Symptom Subtypes Open
Introduction Over 10 years ago, a seminal study using cluster analysis in the Icelandic Sleep Apnea Cohort (ISAC) identified subtypes of patients with obstructive sleep apnea (OSA) defined as excessively sleepy (presenting with multiple sl…
View article: Erradicación de edadismos en los ELEAM ¿Es posible?
Erradicación de edadismos en los ELEAM ¿Es posible? Open
View article: O079 The effect of long-term CPAP on subclinical markers of coronary artery disease in clinic patients with OSA
O079 The effect of long-term CPAP on subclinical markers of coronary artery disease in clinic patients with OSA Open
Background In view of the current uncertainty about the relationship between obstructive sleep apnoea (OSA) and development of major adverse cardiovascular events (MACE) we studied the long-term effect of continuous positive airway pressur…
View article: Why are we not working to prevent OSA?
Why are we not working to prevent OSA? Open
View article: Identifying Risk of Postoperative Cardiorespiratory Complications in OSA
Identifying Risk of Postoperative Cardiorespiratory Complications in OSA Open
These findings provide a basis for better identifying high-risk patients with OSA and determining appropriate postoperative care.
View article: The interrelationships between sleep regularity, obstructive sleep apnea, and hypertension in a middle-aged community population
The interrelationships between sleep regularity, obstructive sleep apnea, and hypertension in a middle-aged community population Open
Study Objectives Little is known about the interrelationships between sleep regularity, obstructive sleep apnea (OSA) and important health markers. This study examined whether irregular sleep is associated with OSA and hypertension, and if…
View article: STREAMLINE: An Automated Machine Learning Pipeline for Biomedicine Applied to Examine the Utility of Photography-Based Phenotypes for OSA Prediction Across International Sleep Centers
STREAMLINE: An Automated Machine Learning Pipeline for Biomedicine Applied to Examine the Utility of Photography-Based Phenotypes for OSA Prediction Across International Sleep Centers Open
While machine learning (ML) includes a valuable array of tools for analyzing biomedical data, significant time and expertise is required to assemble effective, rigorous, and unbiased pipelines. Automated ML (AutoML) tools seek to facilitat…
View article: O006 Major adverse cardiovascular events in severe Obstructive Sleep Apnoea: Associations with symptom subtypes and symptom burden
O006 Major adverse cardiovascular events in severe Obstructive Sleep Apnoea: Associations with symptom subtypes and symptom burden Open
Background Obstructive sleep apnoea (OSA) is a heterogeneous disorder with certain phenotypes at increased risk of major adverse cardiovascular events (MACE). We investigated whether symptom subtypes and/or symptom burden are useful predic…
View article: P074 Sleep-Related Predictors of Road and Workplace Safety in Young Adults: Results from a Community Representative Sample
P074 Sleep-Related Predictors of Road and Workplace Safety in Young Adults: Results from a Community Representative Sample Open
Young adults are at increased risk of road and workplace incidents. Sleep-related predictors of increased risk include short sleep duration, sleep disorders and shift work. It is unknown which predictors are the most impactful, or whether …
View article: O074 Does Sleep Duration, Shift work or Sleep Disorder Status Predict Perceived work Performance and Quality of Life in Young Adults?
O074 Does Sleep Duration, Shift work or Sleep Disorder Status Predict Perceived work Performance and Quality of Life in Young Adults? Open
Young adults are vulnerable to the consequences of disturbed sleep from insufficient sleep, shift work and sleep disorders. The impact of these causes of disturbed sleep on perceived work performance and quality of life (QOL) in young adul…
View article: O054 What Measure of CPAP Treatment is most closely Associated with Reduced Risk of Future Major Cardiovascular Events (MACE)?
O054 What Measure of CPAP Treatment is most closely Associated with Reduced Risk of Future Major Cardiovascular Events (MACE)? Open
Introduction Obstructive sleep apnoea (OSA) is associated with future Major Adverse Cardiovascular Events (MACE). Continuous positive airway pressure (CPAP) is the standard treatment for OSA, but it is not known which measure of CPAP treat…
View article: Early life predictors of obstructive sleep apnoea in young adults: Insights from a longitudinal community cohort (Raine study)
Early life predictors of obstructive sleep apnoea in young adults: Insights from a longitudinal community cohort (Raine study) Open
A range of maternal and neonatal factors predict OSA in young adults, including those related to poor maternal metabolic health, high-risk pregnancy and stressful perinatal events. This information could assist in the early identification …
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Contents Open
View article: Estimating sleep duration: performance of open-source processing of actigraphy compared to in-laboratory polysomnography in the community
Estimating sleep duration: performance of open-source processing of actigraphy compared to in-laboratory polysomnography in the community Open
Comparisons of actigraphy findings between studies are challenging given differences between brand-specific algorithms. This issue may be minimized by using open-source algorithms. However, the accuracy of actigraphy-derived sleep paramete…
View article: Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging
Incidence and Prevalence of Keratoconus Based on Scheimpflug Imaging Open
The prevalence of keratoconus (Belin/Ambrόsio Enhanced Ectasia Display Score ≥2.6 on Scheimpflug imaging) in a longitudinal, community cohort study from Western Australia was 3.4% (n=26/755). Keratoconus incidence over an 8-year period was…
View article: Evaluation of excessive daytime sleepiness in obstructive sleep apnea across international sleep centers
Evaluation of excessive daytime sleepiness in obstructive sleep apnea across international sleep centers Open
Journal Article Evaluation of excessive daytime sleepiness in obstructive sleep apnea across international sleep centers Get access Elin H Thorarinsdottir, Elin H Thorarinsdottir Primary Health Care of the Capital Area, Reykjavik, IcelandF…
View article: Influence of social jetlag on daytime sleepiness in obstructive sleep apnea
Influence of social jetlag on daytime sleepiness in obstructive sleep apnea Open
Summary Social jetlag is the discrepancy between socially determined sleep timing on workdays and biologically determined sleep timing on days free of social obligation. Poor circadian timing of sleep may worsen sleep quality and increase …
View article: Cross‐sectional interrelationships between chronotype, obstructive sleep apnea and blood pressure in a middle‐aged community cohort
Cross‐sectional interrelationships between chronotype, obstructive sleep apnea and blood pressure in a middle‐aged community cohort Open
Summary Chronotype is linked to adverse health measures and may have important associations with obstructive sleep apnea and blood pressure, but data are limited. This study aimed to determine the separate and combined associations of chro…
View article: P103 Associations between sleep regularity, OSA and hypertension in a middle-aged community population
P103 Associations between sleep regularity, OSA and hypertension in a middle-aged community population Open
Little is known about the association of irregular sleep patterns with obstructive sleep apnoea (OSA) and hypertension. This study examined whether irregular sleep patterns determined by the sleep regularity index (SRI) were associated wit…
View article: P109 Predicting major adverse cardiovascular events using symptom subtypes of severe obstructive sleep apnoea
P109 Predicting major adverse cardiovascular events using symptom subtypes of severe obstructive sleep apnoea Open
Background Obstructive sleep apnoea (OSA) is a complex heterogeneous disorder, and patients with similar disease severity present with different symptom profiles and outcomes. It is unclear whether OSA symptom subtypes independently predic…
View article: Shift work, clinically significant sleep disorders and mental health in a representative, cross-sectional sample of young working adults
Shift work, clinically significant sleep disorders and mental health in a representative, cross-sectional sample of young working adults Open
Mental health conditions confer considerable global disease burden in young adults, who are also the highest demographic to work shifts, and of whom 20% meet criteria for a sleep disorder. We aimed to establish the relationship between the…
View article: Telemedicine compared to standard face-to-face care for continuous positive airway pressure treatment: real-world Australian experience
Telemedicine compared to standard face-to-face care for continuous positive airway pressure treatment: real-world Australian experience Open
Study Objectives We tested a telemedicine model of care to initiate continuous positive airway pressure (CPAP) for patients with obstructive sleep apnea (OSA) living in remote Western Australia. Methods A prospective study comparing teleme…
View article: The changing profile of obstructive sleep apnea: long term trends in characteristics of patients presenting for diagnostic polysomnography
The changing profile of obstructive sleep apnea: long term trends in characteristics of patients presenting for diagnostic polysomnography Open
Introduction We aimed to analyze long-term trends in characteristics of patients undergoing diagnostic polysomnography (PSG) and subsequently diagnosed with obstructive sleep apnea (OSA) to inform delivery of sleep services. Material and M…
View article: Prevalence of common sleep disorders in a middle-aged community sample
Prevalence of common sleep disorders in a middle-aged community sample Open
View article: Shift Work, Clinically Significant Sleep Disorders and Mental Health in a Representative, Cross-Sectional Sample of Young Working Adults
Shift Work, Clinically Significant Sleep Disorders and Mental Health in a Representative, Cross-Sectional Sample of Young Working Adults Open
View article: Obstructive Sleep Apnea Symptom Subtypes and Cardiovascular Risk: Conflicting Evidence to an Important Question
Obstructive Sleep Apnea Symptom Subtypes and Cardiovascular Risk: Conflicting Evidence to an Important Question Open
Funding Information: Supported by NIH grant P01 HL094307.
View article: Circulating C-reactive protein levels in patients with suspected obstructive sleep apnea
Circulating C-reactive protein levels in patients with suspected obstructive sleep apnea Open