Explanipedia

AuthAi: Real-Time Behavioral AI for CAPTCHA-Free Security Open

P M Krishna Raj, Priyanshu Kumar, Nikhil Tiwari, D.C. Dwivedi, Sandeep Kaur · 2025

—AuthAI is a marked improvement over traditional, more static methods of authentication (like CAPTCHA - which many may agree is more of a hindrance than a measure of assurance) that typically try to use ”prove you’re not a robot” rituals. …

From treating UTI to agranulocytosis Open

Amit Katyal, Nikhil Tiwari, Vedantam Rajshekhar, Maninder Pal Singh Pardal · 2025

A BSTRACT The growing problem of antibacterial resistance has resulted in increased interest in fosfomycin, especially its parenteral formulation. It is a broad-spectrum antibiotic with both in vivo and in vitro activity against a wide ran…

To Study the Clinical Characteristics, Management and Outcomes in Patients of Necrotising Fasciitis with and Without Diabetes Mellitus Open

x Nishant, Vijay Kumar Goel, Nikhil Tiwari, Dharmendra Uraiya, Suprabha Chaudhary · 2025

Enhanced recovery after cardiac surgery (ERACS) using supraglottic airway and thoracic epidural in pediatric patients: A pilot study Open

Alok Kumar, Neeraj Srivastava, Nihar Ameta, Saajan Joshi, Nikhil Tiwari · 2025

Enhanced recovery after cardiac surgery (ERACS) in pediatric patients using regional anesthesia is a well-recognized modality. However, there is no research on the use of supraglottic devices in pediatric patients under cardiopulmonary byp…

Effectiveness of Three-dimensional Cardiac Computed Tomography Scan in Congenital Heart Surgery–An Impact on Diagnostic Performance and Surgical Management Open

Alok Kumar, Mainak Ganguly, B. Dhanalakshmi, Ritwik Chakrabarti, Arvind Mishra , et al. · 2024

Background: Recent advances in gated cardiac contrast-enhanced computed tomography (CECT) with anesthesia support, enhance the imaging performance in congenital heart disease (CHD). 3D reconstruction of the CECT image is a novel modality t…

Empowering Little Fighters: Post-Cardiotomy Pediatric ECMO and the Journey to Recovery Open

Alok Kumar, Swetha Raj, Saurabh Singh, Gurpinder Singh Ghotra, Nikhil Tiwari · 2024

Introduction: Extra Corporeal Membrane Oxygenation (ECMO) has long been used for cardiorespiratory support in the immediate post-paediatric cardiac surgery period with a 2-3% success as per the ELSO registry. Success in recovery depends up…

Ambulatory milrinone therapy as a bridge to heart transplantation Open

Bhargava V. Devarakonda, Sameer Kumar, Nikhil Tiwari, Nihar Ameta, Saurabh Singh · 2023

Low-Dose Vasopressin and Renal Perfusion in Pediatric Cardiac Surgery Open

Alok Kumar, Gurpinder Singh Ghotra, Swetha Raj, Nikhil Tiwari, H. Ravi Ramamurthy · 2023

Background: Congenital heart surgeries are associated with post-bypass renal and cardiac dysfunctions. The use of low-dose vasopressin has been found to be beneficial in adult cardiac surgeries. Objective: To assess the hemodynamic and ren…

50-years journey of heart transplant Open

Sameer Kumar, Nikhil Tiwari, Saurabh Singh, Kiran Chowdlu Kalappa · 2023

Non-analgesic benefits of combined thoracic epidural analgesia with general anesthesia in on-pump pediatric cardiac surgery: A prospective observational study Open

Alok Kumar, Ravi Kapoor, Shubham Mishra, Ankur Joshi, Nikhil Tiwari , et al. · 2023

High-frequency oscillatory ventilation for respiratory failure after congenital heart surgery: a retrospective analysis Open

Alok Kumar, Ankur Joshi, Badal Parikh, Nikhil Tiwari, Ravi H. Ramamurthy · 2023

Introduction Pulmonary complications such as acute respiratory distress syndrome and refractory respiratory failure have been major causes of morbidity and mortality after cardiac surgery in children. Patients are usually transitioned to e…

Ca2+ Homeostasis by Plasma Membrane Ca2+ ATPase (PMCA) 1 Is Essential for the Development of DP Thymocytes Open

David Beckmann, Kristina Langnaese, Anna Gottfried, Johannes Hradsky, Kerry Tedford , et al. · 2023

The strength of Ca2+ signaling is a hallmark of T cell activation, yet the role of Ca2+ homeostasis in developing T cells before expressing a mature T cell receptor is poorly understood. We aimed to unveil specific functions of the two pla…

Management of Bronchomalacia in Infants Post-Cardiac Surgery Using Synchronized Nasal DuoPAP Open

Alok Kumar, M Praveen, Nikhil Tiwari, H. Ravi Ramamoorthy, Ankur Joshi , et al. · 2022

Background: Tracheo-bronchomalacia (TBM) is the weakness in the structural integrity of the cartilaginous ring and arch. It may occur in isolation with prematurity or secondarily in association with various congenital anomalies. Bronchomal…

Fast-tracking with continuous thoracic epidural analgesia in paediatric congenital heart surgeries: an institutional experience Open

Alok Kumar, H. Ravi Ramamurthy, Nikhil Tiwari, Saajan Joshi, Gaurav Kumar , et al. · 2022

Real time license plate number extraction of non-helmet person using YOLO algorithm Open

S. C. Tirpude, Nikhil Tiwari, Simran Baheti, Rushil Parikh, Deepali Pathe , et al. · 2022

One of the problems in traffic regulations in India is riding motorcycle/mopeds without helmet, which increases accident sand deaths. In the existing system, the traffic police monitor the traffic violations through CCTV recordings, and in…

Hydrogel-Mediated Release of TRPV1 Modulators to Fine Tune Osteoclastogenesis Open

Ranabir Chakraborty, Tusar Kanta Acharya, Nikhil Tiwari, Rakesh Kumar Majhi, Satish Kumar , et al. · 2022

Bone defects, including bone loss due to increased osteoclast activity, have become a global health-related issue. Osteoclasts attach to the bone matrix and resorb the same, playing a vital role in bone remodeling. Ca²⁺ homeosta…

Paediatric complete atrio-ventricular block with atrial septal defect and elevated pulmonary artery pressures: A novel case series Open

Vivek Kumar, Nikhil Tiwari, Sajan Joshi, Ravi Ramamurthy · 2021

Comparative evaluation of high-flow nasal cannula oxygenation vs nasal intermittent ventilation in postoperative paediatric patients operated for acyanotic congenital cardiac defects Open

Alok Kumar, Saajan Joshi, Nikhil Tiwari, Vivek Kumar, H. Ravi Ramamurthy , et al. · 2021

The role of three-dimensional printed cardiac models in the management of complex congenital heart diseases Open

Nikhil Tiwari, H. Ravi Ramamurthy, Vivek Kumar, Alok Kumar, B. Dhanalakshmi , et al. · 2021

A prospective randomized clinical study of perioperative oral thyroid hormone treatment for children undergoing surgery for congenital heart diseases Open

Alok Kumar, Nikhil Tiwari, H. Ravi Ramamurthy, Vivek Kumar, Gaurav Kumar · 2021

Context : Thyroid hormone deficiency is known to occur after cardiac surgery and known as nonthyroid illness (NTI). The beneficial role of perioperative thyroid hormone supplementation in children has been debatable more so with oral suppl…

TRPM8 channel inhibitor-encapsulated hydrogel as a tunable surface for bone tissue engineering Open

Tusar Kanta Acharya, Satish Kumar, Nikhil Tiwari, Arijit Ghosh, Ankit Tiwari , et al. · 2021

Ratio of hydrophobic-hydrophilic and positive-negative residues at lipid-water-interface influences surface expression and channel-gating of TRPV1 Open

Somdatta Saha, Rashmita Das, Divyanshi Divyanshi, Nikhil Tiwari, Ankit Tiwari , et al. · 2020

During evolution, TRPV1 has lost, retained or selected certain residues at Lipid-Water-Interface (LWI) and formed specific patterns there. The ratio of “hydrophobic-hydrophilic” and “positive-negative charged” residues at the inner LWI rem…

Rasmussen’s aneurysm in a child with acute lymphoblastic leukaemia Open

Sanjeev Khera, Ashish Kumar Simalti, Dhanalakshmi Balasubramaniam, Nikhil Tiwari · 2020

A 6-year-old female child was diagnosed with B-lineage acute lymphoblastic leukaemia and was started on intermediate risk Berlin–Frankfurt–Münster 2002 chemotherapy protocol. During week 3 of induction chemotherapy (oral prednisolone, pare…

TLR9 Polymorphisms Might Contribute to the Ethnicity Bias for EBV-Infected Nasopharyngeal Carcinoma Open

Nabanita Roy Chattopadhyay, Koustav Chatterjee, Nikhil Tiwari, Sudipta Chakrabarti, Ashutosh Kumar , et al. · 2020

Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world, but is endemic in some ethnic groups. The association of NPC with the Epstein-Barr virus (EBV) is firmly established; however, the mechanism is still unclear. …

An evolving anesthetic protocol fosters fast tracking in pediatric cardiac surgery: A comparison of two anesthetic techniques Open

Gaurav Kumar, VipulK Sharma, Saajan Joshi, Nikhil Tiwari, Vivek Kumar , et al. · 2019

Ketamine along with low-dose fentanyl, when used for anesthetic induction, in comparison to high-dose fentanyl, reduces postoperative extubation time and ICU stay, in pediatric patients undergoing corrective/palliative surgery under CPB an…

A Clinically Intriguing Case of One Sided Axillary Lipoma and Other Sided Axillary Hidrocystadenoma in the Same Patient- Case Report Open

Nitin Tandon, Nikhil Tiwari, Srivastava AN · 2017

Eccrine Hidrocystadenomas are rare, benign cystic lesions and they occur predominantly on the face usually seen on the eyelids. They have a chronic course and vary with season. These are benign cystic lesions unlike hiradenomas, which are …

Preferential selection of Arginine at the lipid-water-interface of TRPV1 during vertebrate evolution correlates with its snorkeling behaviour and cholesterol interaction Open

Somdatta Saha, Arijit Ghosh, Nikhil Tiwari, Ashutosh Kumar, Abhishek Kumar , et al. · 2017

4 Towards fast tracking following paediatric cardiac surgery: strategy and initial experience with early extubation Open

Giuseppe Pelella, Nikhil Tiwari, Sean Cuddihy, Naveen Raj, A Lotto , et al. · 2017

Objective The aim of this study is to report our initial experience with early extubation ( Methods Early extubation was defined as intraoperative or within 6 hours from arrival to PICU. Between January 2014 to March 2016, 846 patients …

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