Niklas Vesper
YOU?
Author Swipe
View article: finDr: A web server for in silico D-peptide ligand identification
finDr: A web server for in silico D-peptide ligand identification Open
In the rapidly expanding field of peptide therapeutics, the short in vivo half-life of peptides represents a considerable limitation for drug action. D-peptides, consisting entirely of the dextrorotatory enantiomers of naturally occurring …
View article: A Barcoded Flow Cytometric Assay to Explore the Antibody Responses Against SARS-CoV-2 Spike and Its Variants
A Barcoded Flow Cytometric Assay to Explore the Antibody Responses Against SARS-CoV-2 Spike and Its Variants Open
The SARS-CoV-2 pandemic has spread to all parts of the world and can cause life-threatening pneumonia and other severe disease manifestations known as COVID-19. This health crisis has resulted in a significant effort to stop the spread of …
View article: A surrogate cell‐based SARS‐CoV‐2 spike blocking assay
A surrogate cell‐based SARS‐CoV‐2 spike blocking assay Open
To monitor infection by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and successful vaccination against coronavirus disease 2019 (COVID‐19), the kinetics of neutralizing or blocking anti‐SARS‐CoV‐2 antibody titers need …
View article: Engineered chimeric T cell receptor fusion construct (TRuC)-expressing T cells prevent translational shutdown in SARS-CoV-2-infected cells
Engineered chimeric T cell receptor fusion construct (TRuC)-expressing T cells prevent translational shutdown in SARS-CoV-2-infected cells Open
SARS-CoV-2, the causative agent of Covid-19, is known to evade the immune system by several mechanisms. This includes the shutdown of the host cellular protein synthesis, which abrogates the induction of antiviral interferon responses. The…
View article: A symmetric geometry of transmembrane domains inside the B cell antigen receptor complex
A symmetric geometry of transmembrane domains inside the B cell antigen receptor complex Open
Significance The specific activation of B lymphocytes via the binding of antigen to their B cell antigen receptor (BCR) is of central importance for the establishment of humoral immunity and a successful vaccination. A better understanding…