Niklas Westhoff
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View article: Enhancing clinicians’ trust in large language models via transparent source attribution: A randomized controlled evaluation in uro-oncology
Enhancing clinicians’ trust in large language models via transparent source attribution: A randomized controlled evaluation in uro-oncology Open
View article: Urinzytologie als eindeutige Empfehlung der S3-Leitlinie zur Primärdiagnostik des Urothelkarzinom
Urinzytologie als eindeutige Empfehlung der S3-Leitlinie zur Primärdiagnostik des Urothelkarzinom Open
View article: Die infektiöse bakterielle Symphysitis (IBS; Symphysitis pubis purulenta) im urologischen Setting – eine deskriptive Studie und Einführung eines Therapiealgorithmus
Die infektiöse bakterielle Symphysitis (IBS; Symphysitis pubis purulenta) im urologischen Setting – eine deskriptive Studie und Einführung eines Therapiealgorithmus Open
Zusammenfassung Einleitung Eine infektiöse bakterielle Symphysitis (IBS) ist ein schwerwiegendes Krankheitsbild der Symphyse und der parasymphysären Strukturen. Nach einem operativen Eingriff, einer Intervention am unteren Harntrakt oder e…
View article: Tranexamic acid in radical cystectomy: a systematic review and meta-analysis of efficacy and safety
Tranexamic acid in radical cystectomy: a systematic review and meta-analysis of efficacy and safety Open
View article: Removal of EpCAM-positive tumor cells during intraoperative blood salvage– A pivotal multicenter clinical study (REMOVE)
Removal of EpCAM-positive tumor cells during intraoperative blood salvage– A pivotal multicenter clinical study (REMOVE) Open
The study demonstrates the efficacy, safety and feasibility of CATUVAB® for the re-infusion of autologous EC processed by a cell salvage device during high-blood-loss cancer surgeries. These promising results have the potential to re-defin…
View article: En Bloc Transurethral Resection of Bladder Tumors vs Conventional Transurethral Resection of Bladder Tumors for Nonmuscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
En Bloc Transurethral Resection of Bladder Tumors vs Conventional Transurethral Resection of Bladder Tumors for Nonmuscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Open
Purpose: En bloc transurethral resection of bladder tumor (eTURBT) has been proposed as an oncologically comparable alternative to conventional transurethral resection of bladder tumors (cTURBT), with fewer complications and better histolo…
View article: Indocyanine‐guided ureter resection for radical cystectomy – a systematic review and meta‐analysis
Indocyanine‐guided ureter resection for radical cystectomy – a systematic review and meta‐analysis Open
Objectives To perform a systematic review and meta‐analysis of studies comparing indocyanine green (ICG)‐guided resection of ureters with the standard of care during radical cystectomy (RC). Methods The Cochrane Central Register of Control…
View article: Preoperative Physical Activity Improvement with the Use of Activity Trackers in Patients Undergoing Radical Cystectomy—A Bicentric, Open-label, Randomised Controlled Trial: A Clinical Study Protocol of the PreAct Trial
Preoperative Physical Activity Improvement with the Use of Activity Trackers in Patients Undergoing Radical Cystectomy—A Bicentric, Open-label, Randomised Controlled Trial: A Clinical Study Protocol of the PreAct Trial Open
View article: Tranexamic acid reduces perioperative blood transfusions following open radical cystectomy – a propensity-score matched analysis
Tranexamic acid reduces perioperative blood transfusions following open radical cystectomy – a propensity-score matched analysis Open
View article: Quality‐of‐life outcomes of the ROBOtic‐assisted versus Conventional Open Partial nephrectomy (ROBOCOP) II trial
Quality‐of‐life outcomes of the ROBOtic‐assisted versus Conventional Open Partial nephrectomy (ROBOCOP) II trial Open
Objectives To comprehensively compare quality‐of‐life (QoL) outcomes between open partial nephrectomy (OPN) and robot‐assisted PN (RAPN) from the randomised ROBOtic‐assisted versus Conventional Open Partial nephrectomy (ROBOCOP) II trial, …
View article: Do we need MRI in all biopsy naïve patients? A multicenter cohort analysis
Do we need MRI in all biopsy naïve patients? A multicenter cohort analysis Open
Purpose The combined approach (CB) of magnetic resonance imaging (MRI)-guided biopsy (TB) and systematic biopsy (SB) is strongly recommended based on numerous studies in biopsy naïve men with suspicion of clinically significant prostate ca…
View article: Maximizing efficiency and ensuring safety: Exploring the outcomes of 2 consecutive open radical cystectomies by the same team within a single surgical day
Maximizing efficiency and ensuring safety: Exploring the outcomes of 2 consecutive open radical cystectomies by the same team within a single surgical day Open
This study evaluates the outcomes of performing 2 consecutive open radical cystectomies (RC) in a single day by the same surgical team. Data from 657 patients who underwent RC at a single tertiary medical center proved that this approach i…
View article: Evaluation of sexual function and vaginal prolapse after radical cystectomy in women: a study to explore an under-evaluated problem
Evaluation of sexual function and vaginal prolapse after radical cystectomy in women: a study to explore an under-evaluated problem Open
View article: Randomized Controlled Feasibility Trial of Robot-assisted Versus Conventional Open Partial Nephrectomy: The ROBOCOP II Study
Randomized Controlled Feasibility Trial of Robot-assisted Versus Conventional Open Partial Nephrectomy: The ROBOCOP II Study Open
For patients with a kidney tumor, open surgery and robot-assisted keyhole surgery are both feasible and safe approaches for partial removal of the affected kidney. Each approach has known advantages. Long-term follow-up will explore differ…
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View article: Integrin Expression in Localized Prostate Cancer: A TCGA and MSKCC Cohort-based Exploratory<i>In Silico</i>Analysis
Integrin Expression in Localized Prostate Cancer: A TCGA and MSKCC Cohort-based Exploratory<i>In Silico</i>Analysis Open
The utility of ITGs as PC biomarkers was herein shown.
View article: Changes in neutrophile-to-lymphocyte ratio as predictive and prognostic biomarker in metastatic prostate cancer treated with taxane-based chemotherapy
Changes in neutrophile-to-lymphocyte ratio as predictive and prognostic biomarker in metastatic prostate cancer treated with taxane-based chemotherapy Open
Objectives To assess the predictive and prognostic value of changes in longitudinal neutrophile-to-lymphocyte (NLR) ratios in men receiving taxane-based chemotherapy for metastatic prostate cancer (PC). Methods Retrospective, unicentric co…
View article: Systemic inflammatory biomarkers as predictive and prognostic factors in men with metastatic castration-refractory prostate cancer treated with docetaxel therapy: a comprehensive analysis in a German real-world cohort
Systemic inflammatory biomarkers as predictive and prognostic factors in men with metastatic castration-refractory prostate cancer treated with docetaxel therapy: a comprehensive analysis in a German real-world cohort Open
Purpose Advances in therapy of metastatic castration-refractory prostate cancer (mCRPC) resulted in more therapeutic options and led to a higher need of predictive/prognostic biomarkers. Systemic inflammatory biomarkers could provide the b…
View article: Immuntherapien in der Uroonkologie
Immuntherapien in der Uroonkologie Open
Zusammenfassung Hintergrund Immun-Checkpoint-Inhibitoren (ICI) sind seit wenigen Jahren in der Uroonkologie zugelassen. Real-world -Erfahrung zu Nutzen und Risiken bei neuartigen Nebenwirkungen liegt kaum vor. Material und Methoden In eine…
View article: Supplementary Material for: Prospective, Randomized Comparative Evaluation of a Novel Hands-On Endourology Training Curriculum
Supplementary Material for: Prospective, Randomized Comparative Evaluation of a Novel Hands-On Endourology Training Curriculum Open
Introduction: The aim of this randomised prospective trial was to evaluate a novel hands-on endourological training programme (HTP) and compare it to the standard endourological colloquium (SC). Methods: A new H…
View article: Active surveillance inclusion criteria under scrutiny in magnetic resonance imaging-guided prostate biopsy: a multicenter cohort study
Active surveillance inclusion criteria under scrutiny in magnetic resonance imaging-guided prostate biopsy: a multicenter cohort study Open
View article: A prospective study on inter-operator variability in semi-robotic software-based MRI/TRUS-fusion targeted prostate biopsies
A prospective study on inter-operator variability in semi-robotic software-based MRI/TRUS-fusion targeted prostate biopsies Open
View article: ROBOCOP II (ROBOtic assisted versus conventional open partial nephrectomy) randomised, controlled feasibility trial: clinical trial protocol
ROBOCOP II (ROBOtic assisted versus conventional open partial nephrectomy) randomised, controlled feasibility trial: clinical trial protocol Open
Introduction Randomised controlled trials comparing robotic-assisted partial nephrectomy (RAPN) and open PN (OPN) are lacking. Therefore, we aim to report the study protocol and a trial update for a randomised controlled feasibility trial …
View article: Onset And Burden of Lower Limb Lymphedema After Radical Prostatectomy: A Cross-Sectional Study
Onset And Burden of Lower Limb Lymphedema After Radical Prostatectomy: A Cross-Sectional Study Open
ObjectivesTo explore men´s onset and burden of lower limb lymphedema (LLL) after radical prostatectomy (RP) with pelvic lymph node dissection.Patients and methodsA cross-sectional survey-based study was conducted nation-wide and web-based …
View article: Salvage Robotic-assisted Laparoscopic Radical Prostatectomy Following Focal High-Intensity Focused Ultrasound for ISUP 2/3 Cancer
Salvage Robotic-assisted Laparoscopic Radical Prostatectomy Following Focal High-Intensity Focused Ultrasound for ISUP 2/3 Cancer Open
View article: Monoprophylaxis With Cephalosporins for Transrectal Prostate Biopsy After the Fluoroquinolone-Era: A Multi-Institutional Comparison of Severe Infectious Complications
Monoprophylaxis With Cephalosporins for Transrectal Prostate Biopsy After the Fluoroquinolone-Era: A Multi-Institutional Comparison of Severe Infectious Complications Open
Background To compare severe infectious complication rates after transrectal prostate biopsies between cephalosporins and fluoroquinolones for antibiotic monoprophylaxis. Material and Methods In the multi-institutional cohort, between Nove…
View article: Triggers and oncologic outcome of salvage radical prostatectomy, salvage radiotherapy and active surveillance after focal therapy of prostate cancer
Triggers and oncologic outcome of salvage radical prostatectomy, salvage radiotherapy and active surveillance after focal therapy of prostate cancer Open
View article: Peritoneal flap for lymphocele prophylaxis following robotic-assisted laparoscopic radical prostatectomy with pelvic lymph node dissection: study protocol and trial update for the randomized controlled PELYCAN study
Peritoneal flap for lymphocele prophylaxis following robotic-assisted laparoscopic radical prostatectomy with pelvic lymph node dissection: study protocol and trial update for the randomized controlled PELYCAN study Open
View article: Radiomics in Renal Cell Carcinoma—A Systematic Review and Meta-Analysis
Radiomics in Renal Cell Carcinoma—A Systematic Review and Meta-Analysis Open
Radiomics may increase the diagnostic accuracy of medical imaging for localized and metastatic RCC (mRCC). A systematic review and meta-analysis was performed. Doing so, we comprehensively searched literature databases until May 2020. Stud…
View article: Multiparametric prostate MRI and structured reporting: benefits and challenges in the PI-RADS era
Multiparametric prostate MRI and structured reporting: benefits and challenges in the PI-RADS era Open