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Microturbulence across the Hertzsprung–Russell Diagram Open
Context . Despite its critical importance for determining stellar properties and evolution, the origin and physical nature of microturbulence remains poorly understood. Most of the existing works are focussed on specific spectral types and…
Quantum Chemical and Metabolomic Characterization of Inhibitory Activity of Procyanidins and Flavonol Glucosides From <i>Graptopetalum paraguayense</i> E. Walther Against Nonstructural Proteins of SARS‐CoV‐2 Open
This study explores the antiviral potential of Graptopetalum paraguayense against SARS‐CoV‐2 nonstructural proteins (NSPs). G. paraguayense , a plant known for its health benefits, has previously shown strong antiviral activity against HSV…
Electromyographic activities of muscles in the shoulder and elbow joints during elbow flexion-extensions with different velocities in the sagittal and horizontal planes Open
Study aim : Properly processed surface electromyographic signals (EMGs) provide a suitable means for the estimation of muscle activity, including their synergistic and antagonistic action. This study aimed to investigate changes in the act…
Antimalarial and immunomodulatory potential of chalcone derivatives in experimental model of malaria Open
Background Malaria is a complex issue due to the availability of few therapies and chemical families against Plasmodium and mosquitoes. There is increasing resistance to various drugs and insecticides in Plasmodium and in the vector. Addit…
Potential of hydroxybenzoic acids from Graptopetalum paraguayense for inhibiting of herpes simplex virus DNA polymerase – metabolome profiling, molecular docking and quantum-chemical analysis Open
According to our previous investigation the total methanol extract from Graptopetalum paraguayense E. Walther demonstrates a significant inhibitory effect on herpes simplex virus type 1 (HSV-1). To clarify what causes this inhibitory activ…
Potential of Hydroxybenzoic Acids From Graptopetalum paraguayense for Inhibiting of Herpes Simplex Virus DNA Polymerase – Metabolome Profiling, Molecular Docking and Quantum-chemical Analysis Open
According to our previous investigation the total methanol extract from Graptopetalum paraguayense E. Walther demonstrates a significant inhibitory effect on HSV-1. To clarify what causes this inhibitory activity on HSV-1, a metabolic prof…
Potential of Hydroxybenzoic Acids from Graptopetalum paraguayense for Inhibiting of Herpes Simplex Virus DNA Polymerase – Metabolome Profiling, Molecular Docking and Quantum-chemical Analysis Open
According to our previous investigation the total methanol extract from Graptopetalum paraguayense E. Walther demonstrates a significant inhibitory effect on HSV-1. To clarify what causes this inhibitory activity on HSV-1, a metabolic prof…
Antiviral properties of chalcones and their synthetic derivatives: a mini review Open
Chalcones (natural or synthetic derivatives) are aromatic ketones possessing a central backbone that form a core for variety important compounds with different substitutions. Recent scientific advances show that chalcones exhibit different…
Ultrastructural alterations in Plasmodium falciparum induced by chalcone derivatives Open
Objective Chalcones (1, 3-diaryl-2-propen-1-ones) and its derivatives are widely explored from the past decade for its antimalarial activity. To elucidate their mechanism of action on the malaria parasite, the ultrastructural changes with …
Dysbiotic microbiota in autistic children and their mothers: persistence of fungal and bacterial wall-deficient L-form variants in blood Open
Based on our hypothesis for existing microbiota of wall-deficient variants (L-forms) in human blood, we created an innovative methodology, which allowed for the development of L-form populations from blood of all investigated people. In co…
Anti-Herpes Simplex virus and antibacterial activities of <i>Graptopetalum paraguayense</i> E. Walther leaf extract: a pilot study Open
Graptopetalum paraguayense E. Walther (GP) belongs to the Crassulaceae family and has several health benefits. In the present study we evaluated the cytotoxic, anti-Herpes Simplex virus (HSV) and antibacterial activities of a total methano…
View article: Response to comment on "An excess of massive stars in the local 30 Doradus starburst"
Response to comment on "An excess of massive stars in the local 30 Doradus starburst" Open
Farr and Mandel reanalyse our data, finding initial-mass-function slopes for high mass stars in 30 Doradus that agree with our results. However, their reanalysis appears to underpredict the observed number of massive stars. Their technique…
CCDC 1495036: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
CCDC 1495035: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …