Explanipedia

Pituitary apoplexy following heart surgery: a comprehensive review of the literature Open

Theofilos Kanavos, Effrosyni Birbas, Maria Georgiadou, Nikolaos Tsaftaridis · 2025

COVID-19 Related Retinal Vascular Occlusion: A Systematic Review Open

Argyrios Tzamalis, Marina Foti, Maria Georgiadou, Nikolaos Tsaftaridis, Nikolaos Ziakas · 2025

Background/Objectives: To provide insight into populations at higher risk of COVID-19-related retinal vascular occlusion, we identified the baseline characteristics of COVID-19 patients and vaccine recipients who developed this condition b…

Reversal of Direct Oral Anticoagulants (DOACs) for Critical Bleeding or Urgent Procedures Open

Mark Goldin, Nikolaos Tsaftaridis, Jack Jnani, Alex C. Spyropoulos · 2025

The advent of direct-acting oral anticoagulants (DOACs) has transformed the care of patients requiring prevention and treatment for thrombotic disease. Many randomized clinical trials have demonstrated the efficacy and safety of these agen…

Democratizing Virtual Patient Case Creation: A Proof-of-concept Technical Framework for Clinicians Open

Nikolaos Tsaftaridis, Ioannis Koulas, Stefanos Zafeiropoulos, Veauthyelau Saint-Joy, Marwa Ilali , et al. · 2024

Objective Virtual patient cases are a scalable and engaging tool for training medical professionals. Strategies and frameworks for their implementation in teaching and training settings are few, technically complicated and/or expensive. We…

Confluence of Plant-Based Dietary Patterns and Polygenic Risk for Venous Thromboembolism Open

Nikolaos Tsaftaridis · 2024

System-Wide Thromboprophylaxis Interventions for Hospitalized Patients at Risk of Venous Thromboembolism: Focus on Cross-Platform Clinical Decision Support Open

Nikolaos Tsaftaridis, Mark Goldin, Alex C. Spyropoulos · 2024

Thromboprophylaxis of hospitalized patients at risk of venous thromboembolism (VTE) presents challenges owing to patient heterogeneity and lack of adoption of evidence-based methods. Intuitive practices for thromboprophylaxis have resulted…

Clinical Pathways and Outcomes of Andexanet Alfa Administration for the Reversal of Critical Bleeding in Patients on Oral Direct Factor Xa Inhibitors Open

Mark Goldin, Kolton Smith, Ioannis Koulas, Tungming Leung, Mayuri Ravi , et al. · 2024

Background Andexanet is U.S. Food and Drug Administration (FDA) approved for the reversal of critical bleeding from factor Xa inhibitors and off-label for surgical reversal. Data are lacking on andexanet administration processes. Methods W…

System-wide Thromboprophylaxis Interventions for Hospitalized Patients at Risk of Venous Thromboembolism: Focus on Cross-Platform Clinical Decision Support Open

Nikolaos Tsaftaridis, Mark Goldin, Alex C. Spyropoulos · 2024

Thromboprophylaxis of hospitalized patients at risk of venous thromboembolism (VTE) presents challenges owing to patient heterogeneity and lack of adoption of evidence-based methods. Intuitive practices for thromboprophylaxis have resulted…

Relapse of Monoclonal Gammopathy of Renal Significance after mRNA COVID-19 Vaccination: A Case Report Open

Nikolaos Tsaftaridis, Victoria Potoupni, Lydia Koraka, Fotini Iatridi, Γεώργιος Λιούλιος , et al. · 2023

This case report represents the first suspected case of light chain deposition disease relapse associated with mRNA COVID-19 vaccination. The 75-year-old female patient of Greek ethnicity was admitted to the clinic for the investigation of…

Relapse of Monoclonal Gammopathy of Renal Significance after mRNA Covid-19 vaccination: a case report Open

Nikolaos Tsaftaridis, Victoria Potoupni, Lydia Koraka, Foteini Iatridi, Γεώργιος Λιούλιος , et al. · 2022

Introduction This case report represents, to our knowledge, the first suspected case of Light Chain Deposition Disease (LCDD) relapse associated with mRNA COVID-19 vaccination. It must be made clear that timing is the only link between the…

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