Nilesh Jain
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View article: Clinical Profile and Early Outcomes of Neonates With Hypernatremic Dehydration in a Neonatal Intensive Care Unit (NICU) Based in a Tertiary Care Hospital
Clinical Profile and Early Outcomes of Neonates With Hypernatremic Dehydration in a Neonatal Intensive Care Unit (NICU) Based in a Tertiary Care Hospital Open
View article: In-silico ADMET PROFILING AND DOCKING ANALYSIS OF ANTIMALARIAL ACTIVITY OF SULFONAMIDE-ATTACHED COUMARIN- [1,2,3]-TRIAZOLES
In-silico ADMET PROFILING AND DOCKING ANALYSIS OF ANTIMALARIAL ACTIVITY OF SULFONAMIDE-ATTACHED COUMARIN- [1,2,3]-TRIAZOLES Open
Malaria remains a significant global health challenge, particularly in tropical and subtropical regions, with drugresistant Plasmodium strains intensifying the need for new therapies. This study investigates the potential of sulfonamide-at…
View article: Estimation of the effect of acetone- or ethanol-based solvents on shear bond strength of composite resin using air- and blot-dry techniques
Estimation of the effect of acetone- or ethanol-based solvents on shear bond strength of composite resin using air- and blot-dry techniques Open
Background: An adequate amount of water is necessary to maintain the shape of collagen fibrils while excess water hampers dentin–resin bonding. Air-drying lacks control while blot-drying displaces water in a controlled manner. Solvents in …
View article: A STUDY ON FACTORS AFFECTING EMPLOYEE RETENTION RATIO IN IT COMPANIES IN INDIA
A STUDY ON FACTORS AFFECTING EMPLOYEE RETENTION RATIO IN IT COMPANIES IN INDIA Open
The Information Technology (IT) Industry is the fastest-growing industry. In India after 2002 is growing day by day. This is made up of the software industry and the ITES industry and these industries contribute to our Indian economy. It c…
View article: A comprehensive review on the synthesis of mangiferin derivatives and their multiple biological activities
A comprehensive review on the synthesis of mangiferin derivatives and their multiple biological activities Open
Mangiferin, a chemically, oxygen and hydroxyl containing heterocycle and biologically versatile nucleus, has drawn more attention from traditional to modern medicinal chemists in the drug design and synthesis of novel drugs with their phar…
View article: Chemical Characterization of Indian Smokeless tobacco products by spectroscopy, chromatography, and allied techniques: Interproduct Variation
Chemical Characterization of Indian Smokeless tobacco products by spectroscopy, chromatography, and allied techniques: Interproduct Variation Open
Background: This investigation provides an updated study measuring the levels of chemical components for the top-selling smokeless tobacco products (SLT) viz. khaini, mishri, pan masala + tobacco, snus, and tobacco-betel nut mixture in the…
View article: A Comprehensive Review on Biological Activity of Green Tea (Camellia sinensis)
A Comprehensive Review on Biological Activity of Green Tea (Camellia sinensis) Open
Green tea, the commonly consumed beverage, is gaining increased attention in promoting overall health. In specific, green tea is considered a healthful beverage due to the biological activity of its polyphenols namely catechins. The main g…
View article: Early Neurodevelopmental Outcome of Asphyxiated Newborns Treated with Therapeutic Hypothermia: A Non Randomised Cohort Study
Early Neurodevelopmental Outcome of Asphyxiated Newborns Treated with Therapeutic Hypothermia: A Non Randomised Cohort Study Open
Introduction: Therapeutic Hypothermia (TH) is now a proven model of treatment to prevent complications in asphyxiated newborns. Perinatal asphyxia is the leading cause of mortality and disability in India and developing countries. The TH i…
View article: Antioxidant Potential of Cordia dichotoma: A Review
Antioxidant Potential of Cordia dichotoma: A Review Open
Many plants of genus Cordia comprise of trees and shrubs are widely distributed in warmer regions and have been utilized in management of various diseases. Many phytochemicals like flavonoids, alkaloids, terpenes, tannins, and glyceridess …
View article: Formulation, Development and Evaluation of Gastroretentive Sustained Release Tablets of Lansoprazole Using Natural Polymer
Formulation, Development and Evaluation of Gastroretentive Sustained Release Tablets of Lansoprazole Using Natural Polymer Open
The goal of this study is to develop a long-acting Lansoprazole delivery system. Lansoprazole belongs to a class of antisecretory drugs known as substituted benzimidazoles, which decrease gastric acid secretion by inhibiting the (H+,K+)-AT…
View article: A rare case of extra-gonadal mixed germ cell tumour of seminal vesicle
A rare case of extra-gonadal mixed germ cell tumour of seminal vesicle Open
View article: Contralateral Trigeminal Neuralgia Due to Left Petroclival Meningioma an Extremely Rare Presentation: A Case Report
Contralateral Trigeminal Neuralgia Due to Left Petroclival Meningioma an Extremely Rare Presentation: A Case Report Open
View article: Impact of hydroxyurea therapy on clinicohematological parameters in children with sickle cell anemia
Impact of hydroxyurea therapy on clinicohematological parameters in children with sickle cell anemia Open
Background: Sickle cell anemia (SCA) is an autosomal recessive disorder associated with high morbidity and mortality in children. Hydroxyurea (HU) has shown to decrease the frequency of vaso-occlusive crisis, hospitalization, and blood tra…
View article: Formulation and In Vitro Evaluation of Bilayer Tablets of Lansoprazole and Amoxycillin Trihydrate for the Treatment of Peptic Ulcer
Formulation and In Vitro Evaluation of Bilayer Tablets of Lansoprazole and Amoxycillin Trihydrate for the Treatment of Peptic Ulcer Open
The present work involves the formulation development, optimization and In-vitro evaluation of bilayer tablet containing Lansoprazole in the immediate release layer and Amoxycillin in the sustained release layer, using sodium starch glycol…
View article: Formulation and Evaluation of Orodispersible Tablet of Fluvastatin Sodium
Formulation and Evaluation of Orodispersible Tablet of Fluvastatin Sodium Open
The purpose of this research work is to formulate and evaluate the Orodispersible tablet of Fluvastatin Sodium to enhance the bioavailability and effectiveness of the drug. The objectives of the drug work were to formulate and evaluate Oro…
View article: BOSWELLIA SERRATA ROXB. – A BIOACTIVE HERBS WITH VARIOUS PHARMACOLOGICAL ACTIVITIES
BOSWELLIA SERRATA ROXB. – A BIOACTIVE HERBS WITH VARIOUS PHARMACOLOGICAL ACTIVITIES Open
Herbal medicine has become a medicinal as well as the economic aspect of global significance. While the use of these herbal medicines has increased, there are several questions about their consistency, protection, and effectiveness in diff…
View article: SARS – COV-2 (COVID-19) Pandemic: A Critical Review on Novel Coronavirus Pathogenesis, Clinical Diagnosis and Treatment
SARS – COV-2 (COVID-19) Pandemic: A Critical Review on Novel Coronavirus Pathogenesis, Clinical Diagnosis and Treatment Open
The 2019-nCoV is officially called SARS-CoV-2 and the disease is named COVID-19. The Novel coronavirus (SARS-CoV-2) caused pneumonia in Wuhan, China in December 2019 is a highly contagious disease. The World Health Organization (WHO) has d…
View article: Formulation and Evaluation of Protein Bound Paclitaxel Nanoparticles for Injectable Suspension
Formulation and Evaluation of Protein Bound Paclitaxel Nanoparticles for Injectable Suspension Open
Aims: The aim of present study is to develop Paclitaxel nanoparticles for injectable suspension, an anti-neoplastic drug formulation.
Study design: Mention the design of the study here.
Place and Duration of Study: Sagar Institute of Res…
View article: A complete removal of parapharyngeal space schwannoma: A rare case report with review of literature
A complete removal of parapharyngeal space schwannoma: A rare case report with review of literature Open
View article: A rare case of bilateral congenital upper eyelid eversion managed conservatively
A rare case of bilateral congenital upper eyelid eversion managed conservatively Open
A 12-h-old female infant was referred to our tertiary care hospital from another hospital for the management of eversion of both upper eyelids. The full-term neonate was born by cesarean section for failed induction of labor. On ocular exa…
View article: The Effect of Population Density, Urbanization and Tobacco Use on the Spread and Recovery Rate of COVID-19 in India
The Effect of Population Density, Urbanization and Tobacco Use on the Spread and Recovery Rate of COVID-19 in India Open
View article: Preliminary evaluation of melatonin in the kindling model of epilepsy
Preliminary evaluation of melatonin in the kindling model of epilepsy Open
During the past decades, epilepsy syndrome has been depicted across India as well as worldwide and this leads to increasing mortality and morbidity rate. Researchers are trying to investigate the responsible causes and risk factors for sei…
View article: Advances in green synthesis of nanoparticles
Advances in green synthesis of nanoparticles Open
Nanotechnology is a developing branch of pharmaceutical sciences wherein the particles extend in nanosizes and turn out to be more responsive when contrasted with their unique counter parts. In the past numerous years, the utilization of s…
View article: FORMULATION AND EVALUATION OF ANTIFUNGAL CREAM USING NELUMBO NUCIFERA AND AZADIRACHTA INDICA LEAVES EXTRACTS
FORMULATION AND EVALUATION OF ANTIFUNGAL CREAM USING NELUMBO NUCIFERA AND AZADIRACHTA INDICA LEAVES EXTRACTS Open
The main aim of this investigation was to evaluate the antifungal activity of leaves of Nelumbo nucifera (Nelumbonacaea) and Azadirachta indica (Meliacaea).Study involved qualitative estimation of the methanolic and ethanolic extracts of N…
View article: CCDC 1530940: Experimental Crystal Structure Determination
CCDC 1530940: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Pharmaceutical aspects of silver nanoparticles
Pharmaceutical aspects of silver nanoparticles Open
Silver nanoparticles are particles in the size ranging between 1 and 100 nm. The two major methods used for synthesis of silver nanoparticle are the physical and chemical methods with the disadvantage that they are expensive and can also h…
View article: Pharmaceutical potential of quantum dots
Pharmaceutical potential of quantum dots Open
Quantum dots (QDs) or fluorescent nanocrystals are designed nanoparticles that are promising for several biological and bio-medical applications as well as drug delivery and simultaneous cellular imaging. QD's have exhibited promising pote…