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View article: Paediatric parapneumonic effusion – a twenty-year clinical narrative
Paediatric parapneumonic effusion – a twenty-year clinical narrative Open
Purpose Paediatric parapneumonic effusion (PPE) is accompanied by an increased risk of complications, e.g., sepsis or lung sequelae. Treatment strategies span from antibiotics alone to surgical interventions, but an internationally accepte…
View article: Mental health in children admitted with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): a follow-up study at 6 months of the Swissped-RECOVERY trial
Mental health in children admitted with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): a follow-up study at 6 months of the Swissped-RECOVERY trial Open
Background PIMS-TS presents with features considered to pose a risk for the development of unfavourable long-term mental health outcomes which haven’t been prospectively investigated. These include neurological symptoms (headache, confusio…
View article: Syphilis in pregnant women and congenital syphilis from 2012 to 2021 in Switzerland: a multicentre, retrospective study
Syphilis in pregnant women and congenital syphilis from 2012 to 2021 in Switzerland: a multicentre, retrospective study Open
BACKGROUND AND AIMS OF THE STUDY: Congenital syphilis is a rare complication of syphilis in pregnant women. Vertical transmission may occur at any time during pregnancy. The incidence of congenital syphilis has been increasing worldwide. C…
View article: Planetary Health: What You Need to Know as a Pediatric Infectious Diseases Doctor
Planetary Health: What You Need to Know as a Pediatric Infectious Diseases Doctor Open
View article: Ongoing Excess Hospitalizations for Severe Pediatric Group a Streptococcal Disease in 2023–2024 – a Single Center Report
Ongoing Excess Hospitalizations for Severe Pediatric Group a Streptococcal Disease in 2023–2024 – a Single Center Report Open
A Europe-wide outbreak of invasive pediatric Group a streptococcal infections (iGAS) began in fall 2022. Here we report the evolution of GAS hospitalizations in children and adolescents during the second outbreak year in 2023-2024 at a ter…
View article: Ongoing Excess Hospitalizations for Severe Pediatric Group A Streptococcal Disease
Ongoing Excess Hospitalizations for Severe Pediatric Group A Streptococcal Disease Open
Objectives A major, Europe-wide outbreak of invasive pediatric Group A streptococcal infections (iGAS) began in late fall 2022. Here we report the evolution of GAS hospitalizations in children and adolescents during the second outbreak yea…
View article: Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in Switzerland
Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in Switzerland Open
Objectives In trials of acute severe infections or inflammations frequent administration of non-randomised treatment (ie, intercurrent event) in response to clinical events is expected. These events may affect the interpretation of trial f…
View article: Tularemia on the rise in Switzerland? A one health approach is needed!
Tularemia on the rise in Switzerland? A one health approach is needed! Open
View article: Preadmission course and management of severe pediatric group A streptococcal infections during the 2022–2023 outbreak: a single-center experience
Preadmission course and management of severe pediatric group A streptococcal infections during the 2022–2023 outbreak: a single-center experience Open
Purpose The massive increase of infections with Group A Streptococcus (GAS) in 2022–2023 coincided in Switzerland with a change of the recommendations for the management of GAS pharyngitis. Therefore, the objective of the present study was…
View article: COVID-19 Vaccine Acceptance Among Parents of Children With Multisystem Inflammatory Syndrome in Children
COVID-19 Vaccine Acceptance Among Parents of Children With Multisystem Inflammatory Syndrome in Children Open
Data on COVID-19 vaccine acceptability among parents of children with multisystem inflammatory syndrome (MIS-C) are limited. In this cohort of children with MIS-C, enrolled in the Swissped RECOVERY trial (NCT 04826588), comparing intraveno…
View article: The changing clinical presentation of <scp>COVID</scp>‐19 in children during the course of the pandemic
The changing clinical presentation of <span>COVID</span>‐19 in children during the course of the pandemic Open
Aim To investigate the evolution of clinical symptoms of COVID‐19 in children throughout the pandemic. Methods In this national prospective surveillance study, symptoms in children hospitalised with COVID‐19 were collected from all paediat…
View article: Seroepidemiology of Human Tularemia—Systematic Review and Meta-analysis of Seroprevalence Studies
Seroepidemiology of Human Tularemia—Systematic Review and Meta-analysis of Seroprevalence Studies Open
Background Seroepidemiologic studies of human tularemia have been conducted throughout the northern hemisphere. The purposes of this study were (1) to provide an overview of Francisella tularensis seroprevalence data, and (2) to generate a…
View article: Cardiac assessment and inflammatory markers in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV2 (PIMS-TS) treated with methylprednisolone versus intravenous immunoglobulins: 6-month follow-up outcomes of the randomised controlled Swissped RECOVERY trial
Cardiac assessment and inflammatory markers in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV2 (PIMS-TS) treated with methylprednisolone versus intravenous immunoglobulins: 6-month follow-up outcomes of the randomised controlled Swissped RECOVERY trial Open
View article: Cardiac involvement in children with paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS): data from a prospective nationwide surveillance study
Cardiac involvement in children with paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS): data from a prospective nationwide surveillance study Open
BACKGROUND: Paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) may occur 4 to 8 weeks after SARS-CoV-2 infection. The acute presentation of PIMS-TS has been well described, but data on longer-term …
View article: Sur les lieux d’un cas infectiologique – enquête diagnostique: réflexions à propos des indications et limites des analyses microbiologiques courantes
Sur les lieux d’un cas infectiologique – enquête diagnostique: réflexions à propos des indications et limites des analyses microbiologiques courantes Open
Les moyens diagnostiques en infectiologie ont connu ces dernières années une expansion grâce notamment aux moyens de détection de la génétique moléculaire. Les différentes analyses ont leur place dans le diagnostic d’une maladie infectieus…
View article: Tatort infektiologischer Fall – mit Diagnostik auf Spurensuche: Überlegungen zu Indikationen und Limitationen gebräuchlicher mikrobiologischer Nachweismethoden
Tatort infektiologischer Fall – mit Diagnostik auf Spurensuche: Überlegungen zu Indikationen und Limitationen gebräuchlicher mikrobiologischer Nachweismethoden Open
Die diagnostischen Möglichkeiten in der Infektiologie haben in den letzten Jahren vor allem durch molekulargenetische Nachweismethoden eine Erweiterung erfahren. Bei der Abklärung von Infektionskrankheiten haben die unterschiedlichen Analy…
View article: Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial
Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial Open
View article: Kawasaki Disease Triggering an Episode of Psoriasis – a Case Report
Kawasaki Disease Triggering an Episode of Psoriasis – a Case Report Open
Kawasaki disease (KD) is an acute systemic inflammatory illness causing vasculitis. A diffuse polymorphous rash is one of the predominant features of patients presenting with KD. This rash can have a morbilliform, urticarial, micropustular…
View article: Pediatric Tularemia—A Case Series From a Single Center in Switzerland
Pediatric Tularemia—A Case Series From a Single Center in Switzerland Open
Background The incidence of tularemia has recently increased throughout Europe. Pediatric tularemia typically presents with ulceroglandular or glandular disease and requires antimicrobial therapy not used in the empirical management of chi…
View article: Multicenter Randomized Trial of Methylprednisolone vs. Intravenous Immunoglobulins to Treat the Pediatric Inflammatory Multisystem Syndrome—Temporally Associated With SARS-CoV-2 (PIMS-TS): Protocol of the Swissped RECOVERY Trial
Multicenter Randomized Trial of Methylprednisolone vs. Intravenous Immunoglobulins to Treat the Pediatric Inflammatory Multisystem Syndrome—Temporally Associated With SARS-CoV-2 (PIMS-TS): Protocol of the Swissped RECOVERY Trial Open
Introduction In 2020, a new disease entitled Pediatric Inflammatory Multisystem Syndrome temporally associated with COVID-19 (PIMS-TS), or Multisystem Inflammatory Syndrome in Children (MIS-C), emerged, with thousands of children affected …
View article: Best Practice Recommendations for the Diagnosis and Management of Children With Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 (PIMS-TS; Multisystem Inflammatory Syndrome in Children, MIS-C) in Switzerland
Best Practice Recommendations for the Diagnosis and Management of Children With Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 (PIMS-TS; Multisystem Inflammatory Syndrome in Children, MIS-C) in Switzerland Open
Background: Following the spread of the coronavirus disease 2019 (COVID-19) pandemic a new disease entity emerged, defined as Pediatric Inflammatory Multisystem Syndrome temporally associated with COVID-19 (PIMS-TS), or Multisystem Inflamm…
View article: Cerebrospinal fluid CXCL13 as a diagnostic marker of neuroborreliosis in children: a retrospective case-control study
Cerebrospinal fluid CXCL13 as a diagnostic marker of neuroborreliosis in children: a retrospective case-control study Open