Nan Peng
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View article: Profound dFLC decrease after one cycle predicts superior outcome in patients with AL amyloidosis
Profound dFLC decrease after one cycle predicts superior outcome in patients with AL amyloidosis Open
The relationship between an early decrease in the difference between involved and uninvolved free light chains (dFLC) and clinical outcomes in AL amyloidosis is significant. We conducted a multicenter study (n = 86, baseline dFLC ≥ …
View article: Reengineering of ergosterol biosynthesis in Saccharomyces cerevisiae and its sustainable application in citrus peel processing industry
Reengineering of ergosterol biosynthesis in Saccharomyces cerevisiae and its sustainable application in citrus peel processing industry Open
Ergosterol is an important sterol primarily found in fungi, yeast, and certain plants, with particularly high concentrations in yeast and fungus. As the precursor to vitamin D2, it is converted into vitamin D2 upon ex…
View article: Age-related differences in activities of daily living among older Chinese adults
Age-related differences in activities of daily living among older Chinese adults Open
The decline in activities of daily living (ADL) significantly impacts independence and quality of life among older adults. This study used data from the China Health and Retirement Longitudinal Study (CHARLS) to conduct a cross-sectional a…
View article: Immune cells: the key mediator between the gut microbiota and osteoporosis
Immune cells: the key mediator between the gut microbiota and osteoporosis Open
As the body’s largest immunological interface, the intestine harbors a complex ecosystem of gut microbiota (GM) that orchestrates mucosal immune maturation while sustaining local immunological equilibrium. Emerging evidence reveals the gut…
View article: RWD110 POLYPHARMACY AND RISK OF MAJOR CARDIOVASCULAR EVENTS AMONG CHINESE PATIENTS WITH DIABETES: A RETROSPECTIVE COHORT STUDY USING INSTRUMENTAL VARIABLE ANALYSIS
RWD110 POLYPHARMACY AND RISK OF MAJOR CARDIOVASCULAR EVENTS AMONG CHINESE PATIENTS WITH DIABETES: A RETROSPECTIVE COHORT STUDY USING INSTRUMENTAL VARIABLE ANALYSIS Open
View article: Improving nutritional quality and aflatoxin detoxification of peanut meal by co-fermentation with Weizmannia coagulans, Bacillus subtilis, and supplemented enzymes
Improving nutritional quality and aflatoxin detoxification of peanut meal by co-fermentation with Weizmannia coagulans, Bacillus subtilis, and supplemented enzymes Open
View article: Impact of exposure to ambient air pollution on health related quality of life of rural elderly in western China
Impact of exposure to ambient air pollution on health related quality of life of rural elderly in western China Open
View article: Investigation on the dynamic response of aerostatic bearing-rotor system with different bearing gases
Investigation on the dynamic response of aerostatic bearing-rotor system with different bearing gases Open
Due to their low friction and long lifespan, aerostatic bearings are widely used in high-speed cryogenic turbo expanders. Variations in bearing gas viscosity and density lead to differences in the static and dynamic characteristics of thes…
View article: Numerical Simulation of the Protective Effect of Air Walls on Liquid Hydrogen Leakage
Numerical Simulation of the Protective Effect of Air Walls on Liquid Hydrogen Leakage Open
Liquid hydrogen storage stands out among various storage and transportation methods for its high efficiency. However, accidental leaks of liquid hydrogen pose safety hazards due to the formation of hydrogen clouds. Therefore, a research pr…
View article: Phenotypic adaptation and genomic variation of Kandelia obovata associated with its northern introduction along southeastern coast of China
Phenotypic adaptation and genomic variation of Kandelia obovata associated with its northern introduction along southeastern coast of China Open
Introduction Mangroves play a crucial role within coastal wetland ecosystems, with Kandelia obovata frequently utilized for introduction studies and cultivation research. Investigating the rapid adaptability of K. obovata across diverse en…
View article: Native synthetic microbial communities enhance zha‐chili by boosting the fermentation capacity of indigenous microorganisms
Native synthetic microbial communities enhance zha‐chili by boosting the fermentation capacity of indigenous microorganisms Open
Fermented foods are a crucial part of the global diet, accounting for one‐third of global food intake. Traditional fermented foods often rely on natural fermentation, leading to safety risks. The construction of synthetic microbial communi…
View article: Unlocking the Potential of Freeze‐Dried Broccoli Powder: A Novel Approach to Enhancing Cognitive Resilience in Temporal Lobe Epilepsy
Unlocking the Potential of Freeze‐Dried Broccoli Powder: A Novel Approach to Enhancing Cognitive Resilience in Temporal Lobe Epilepsy Open
Cognitive impairment frequently accompanies temporal lobe epilepsy (TLE), which is linked to oxidative stress. Freeze‐dried broccoli powder (BROC) exhibits diverse biological activities, particularly its antioxidant properties. Our study e…
View article: Interpretable machine learning approaches for children’s ADHD detection using clinical assessment data: an online web application deployment
Interpretable machine learning approaches for children’s ADHD detection using clinical assessment data: an online web application deployment Open
Our findings highlight the potential of using machine learning and clinical assessment scales to support the diagnosis and subtype identification of ADHD in children, offering a practical solution for improving diagnostic accuracy and effi…
View article: Isolation and Whole-Genome Sequencing of Antibiotic-Resistant Bacteria Revealed the Reservoir for Indigenous Antibiotic Resistance Genes in the Deepest Ocean Sediment of the Challenger Deep
Isolation and Whole-Genome Sequencing of Antibiotic-Resistant Bacteria Revealed the Reservoir for Indigenous Antibiotic Resistance Genes in the Deepest Ocean Sediment of the Challenger Deep Open
View article: Innovation of Multimodal Learning Paths Based on Learning Behavior and Sentiment Analysis in AI Digital Intelligence Platform
Innovation of Multimodal Learning Paths Based on Learning Behavior and Sentiment Analysis in AI Digital Intelligence Platform Open
View article: Optimization and Flow Field Analysis of a Helium Turbo Expander Impeller for a 5 Tpd Hydrogen Liquefier Using the Cppid Method
Optimization and Flow Field Analysis of a Helium Turbo Expander Impeller for a 5 Tpd Hydrogen Liquefier Using the Cppid Method Open
View article: Modeling and Assessment of Tritium Environmental Migration During Decommissioning of a Heavy Water Research Reactor
Modeling and Assessment of Tritium Environmental Migration During Decommissioning of a Heavy Water Research Reactor Open
View article: Performance Analysis of High-Speed Brake Impellers in Cryogenic Helium Turbo-Expander
Performance Analysis of High-Speed Brake Impellers in Cryogenic Helium Turbo-Expander Open
View article: Analysis of the Eddy Current Characteristics and Energy Loss of the High-Speed Cryogenic Helium Turbo-Expander Brake Impeller
Analysis of the Eddy Current Characteristics and Energy Loss of the High-Speed Cryogenic Helium Turbo-Expander Brake Impeller Open
View article: Comparative plastomic analysis of cultivated Dioscorea polystachya and its close relatives provides insights on the inter- and intraspecific phylogenies and potential wild origins of domestication
Comparative plastomic analysis of cultivated Dioscorea polystachya and its close relatives provides insights on the inter- and intraspecific phylogenies and potential wild origins of domestication Open
Phylogenetic analysis supports that Huaishan yams are not of monophyletic origin and the cultivated Chinese yam has at least two wild origins of domestication, which is consistent with the historical records of these wild yams from Mt. Dab…
View article: Author Correction: Collateral nuclease activity of TnpB triggered by high temperature enables fast and sensitive nucleic acid detection
Author Correction: Collateral nuclease activity of TnpB triggered by high temperature enables fast and sensitive nucleic acid detection Open
View article: A multispatial information representation model emphasizing key brain regions for Alzheimer’s disease diagnosis with structural magnetic resonance imaging
A multispatial information representation model emphasizing key brain regions for Alzheimer’s disease diagnosis with structural magnetic resonance imaging Open
The MSRNet model could conduct an effective multispatial information representation in the sMRI-based diagnosis of AD. The proposed interaction mechanism in the MSRNet could help the model focus on AD-related brain regions, thus further im…
View article: Collateral nuclease activity of TnpB triggered by high temperature enables fast and sensitive nucleic acid detection
Collateral nuclease activity of TnpB triggered by high temperature enables fast and sensitive nucleic acid detection Open
View article: Early dFLC response by C1D7 predicts complete hematologic response in systemic AL amyloidosis
Early dFLC response by C1D7 predicts complete hematologic response in systemic AL amyloidosis Open
View article: Combined metformin and simvastatin therapy inhibits SREBP2 maturation and alters energy metabolism in glioma
Combined metformin and simvastatin therapy inhibits SREBP2 maturation and alters energy metabolism in glioma Open
View article: Interpretable Machine Learning Approaches for Children's ADHD Detection Using Clinical Assessment Data: An online web application deployment
Interpretable Machine Learning Approaches for Children's ADHD Detection Using Clinical Assessment Data: An online web application deployment Open
Background Attention-deficit/hyperactivity disorder (ADHD) is a prevalent mental disorder characterized by hyperactivity, impulsivity, and inattention. This study aims to develop a verifiable and interpretable machine learning model to ide…
View article: Geographic Variation in Microbes and Water Quality in Urban Lakes Restored with Submerged Plants: Migration of Microbial Communities Across Habitats
Geographic Variation in Microbes and Water Quality in Urban Lakes Restored with Submerged Plants: Migration of Microbial Communities Across Habitats Open
As an important component of urban ecology, the water quality in urban lakes directly affects the stability of the entire ecosystem. However, with the acceleration of urbanization, the eutrophication of urban lakes has become increasingly …
View article: Numerical Computation and Experimental Research for Dynamic Properties of Ultra-High-Speed Rotor System Supported by Helium Hydrostatic Gas Bearings
Numerical Computation and Experimental Research for Dynamic Properties of Ultra-High-Speed Rotor System Supported by Helium Hydrostatic Gas Bearings Open
This study delves into the dynamic behavior of ultra-high-speed rotor systems underpinned by helium hydrostatic gas bearings, with a focus on the impact of rotational velocity on system performance. We have formulated an integrative dynami…
View article: SVIP reduces IGFBP-2 expression and inhibits glioblastoma progression via stabilizing PTEN
SVIP reduces IGFBP-2 expression and inhibits glioblastoma progression via stabilizing PTEN Open
View article: Characteristics and Functions of Dominant Yeasts Together with Their Applications during Strong-Flavor Baijiu Brewing
Characteristics and Functions of Dominant Yeasts Together with Their Applications during Strong-Flavor Baijiu Brewing Open
Yeasts are pivotal brewing microbes that are associated with the flavor and quality of Chinese baijiu, yet research on dominant yeasts in strong-flavor baijiu brewing remains limited. In this study, Saccharomyces cerevisiae, Pichia kudriav…