Ning Peng
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View article: Prognostic value of radiological and pathological complete response following immune-based conversion therapy in patients with unresectable hepatocellular carcinoma (GUIDANCE004)
Prognostic value of radiological and pathological complete response following immune-based conversion therapy in patients with unresectable hepatocellular carcinoma (GUIDANCE004) Open
It is unclear whether radiological and pathological complete responses after immune-based conversion therapy are associated with each other and with the prognosis of patients with initially unresectable hepatocellular carcinoma. This large…
View article: Correction: The efficacy and safety of tislelizumab with or without tyrosine kinase inhibitor as adjuvant therapy in hepatocellular carcinoma with high-risk of recurrence after curative resection
Correction: The efficacy and safety of tislelizumab with or without tyrosine kinase inhibitor as adjuvant therapy in hepatocellular carcinoma with high-risk of recurrence after curative resection Open
[This corrects the article DOI: 10.3389/fimmu.2025.1593153.].
View article: The efficacy and safety of tislelizumab with or without tyrosine kinase inhibitor as adjuvant therapy in hepatocellular carcinoma with high-risk of recurrence after curative resection
The efficacy and safety of tislelizumab with or without tyrosine kinase inhibitor as adjuvant therapy in hepatocellular carcinoma with high-risk of recurrence after curative resection Open
Background Multiple studies have demonstrated that adjuvant therapy with programmed death-1 (PD-1) inhibitors can enhance the recurrence-free survival of patients with hepatocellular carcinoma (HCC) following curative resection. This study…
View article: Cold Stress Responses of Different Genotypes of Miscanthus Assessed by Relative Electrical Conductivity and LT50
Cold Stress Responses of Different Genotypes of Miscanthus Assessed by Relative Electrical Conductivity and LT50 Open
We aim to provide a theoretical basis for improving the cold tolerance of Miscanthus spp., a widely recognized C4 perennial bioenergy crop, and extending its application in the industry. This study evaluated its cold tolerance by measuring…
View article: Echinacoside improves memory function and bone mineral density in aged SAMP8 mouse model
Echinacoside improves memory function and bone mineral density in aged SAMP8 mouse model Open
Background Alzheimer’s disease (AD) and osteoporosis (OP) are prevalent age-related degenerative diseases that often coexist. Echinacoside (ECH) has been extensively studied for its potential to mitigate AD and bone mineral density (BMD) l…
View article: Survival benefit of hepatectomy after complete or partial response to conversion therapy in unresectable hepatocellular carcinoma (GUIDANCE003): a multi-center study
Survival benefit of hepatectomy after complete or partial response to conversion therapy in unresectable hepatocellular carcinoma (GUIDANCE003): a multi-center study Open
Introduction: The uncertainty exists regarding whether hepatectomy enhances the prognosis for initially unresectable hepatocellular carcinoma (HCC) that becomes resectable subsequent to conversion therapy. This study conducted a comparativ…
View article: Structural characteristics of Saccharomyces cerevisiae mannoprotein and its immunomodulatory activities on RAW264.7 cells
Structural characteristics of Saccharomyces cerevisiae mannoprotein and its immunomodulatory activities on RAW264.7 cells Open
An enzyme-extracted mannoprotein (SC-MP) from the cell wall of Saccharomyces cerevisiae was investigated for structural characteristics and immunomodulatory effects on RAW264.7. The SC-MP was purified using the diethylaminoethyl (DEAE) cel…
View article: Raptin, a sleep-induced hypothalamic hormone, suppresses appetite and obesity
Raptin, a sleep-induced hypothalamic hormone, suppresses appetite and obesity Open
Sleep deficiency is associated with obesity, but the mechanisms underlying this connection remain unclear. Here, we identify a sleep-inducible hypothalamic protein hormone in humans and mice that suppresses obesity. This hormone is cleaved…
View article: Methyltransferase METTL3 regulates neuropathic pain through m6A methylation modification of SOCS1
Methyltransferase METTL3 regulates neuropathic pain through m6A methylation modification of SOCS1 Open
The mechanisms of neuropathic pain (NP) are considered multifactorial. Alterations in the suppressor of cytokine signaling 1 (SOCS1) play a critical role in neural damage and inflammation. Epigenetic RNA modifications, specifically N6-meth…
View article: Clinical Study on the Therapeutic Effect of Combined Traditional Chinese Medicine with Acupoint Injection and Herbal Paste Application in Treating Ovulatory Dysfunction in Polycystic Ovary Syndrome (PCOS)
Clinical Study on the Therapeutic Effect of Combined Traditional Chinese Medicine with Acupoint Injection and Herbal Paste Application in Treating Ovulatory Dysfunction in Polycystic Ovary Syndrome (PCOS) Open
Objective: To observe the therapeutic effect of combined traditional Chinese medicine (TCM) therapy with acupoint injection and herbal patch application on patients with ovulatory dysfunction associated with polycystic ovary syndrome (PCOS…
View article: Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells
Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells Open
A major unmet need in the cystic fibrosis (CF) therapeutic landscape is the lack of effective treatments for nonsense CFTR mutations, which affect approximately 10% of CF patients. Correction of nonsense CFTR mutations via genomic editing …
View article: K-Means Module Division Method of FDM3D Printer-Based Function–Behavior–Structure Mapping
K-Means Module Division Method of FDM3D Printer-Based Function–Behavior–Structure Mapping Open
Product performance, function, cost, and the level of module generalization are all significantly influenced by product modular design, but different goods require different division indicators and techniques. The purpose of this study is …
View article: Letter: repeat hepatic resection versus radiofrequency ablation for recurrent hepatocellular carcinoma in ideal candidates
Letter: repeat hepatic resection versus radiofrequency ablation for recurrent hepatocellular carcinoma in ideal candidates Open
LINKED CONTENT This article is linked to Tong et al papers. To view these articles, visit https://doi.org/10.1111/apt.17263 and https://doi.org/10.1111/apt.17423
View article: Path Planning and Trajectory Optimization Based on Improved APF and Multi-Target
Path Planning and Trajectory Optimization Based on Improved APF and Multi-Target Open
Aiming at the shortcomings of the path generated by the artificial potential field (APF) method, such as local minimum, target unreachability, and low path smoothness, an improved artificial potential field method is proposed. First, to re…
View article: Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model
Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in more severe syndromes and poorer outcomes in patients with diabetes and obesity. However, the precise mechanisms responsible for the combined impact of co…
View article: Ulnar-Mammary syndrome with <i>TBX3</i> gene mutation in a Chinese family: A case report and literature review.
Ulnar-Mammary syndrome with <i>TBX3</i> gene mutation in a Chinese family: A case report and literature review. Open
Ulnar-Mammary syndrome (UMS) is a rare monogenic disorder caused by mutations of the TBX3 gene. This paper reported a family of UMS. The proband, a 15-year old man, was presented with mammary gland dysplasia, ulnar limb defect, short statu…
View article: Effect of tiotropium bromide, N-acetylcysteine and respiratory training on pulmonary function, activity tolerance and quality of life of patients with chronic obstructive pulmonary disease
Effect of tiotropium bromide, N-acetylcysteine and respiratory training on pulmonary function, activity tolerance and quality of life of patients with chronic obstructive pulmonary disease Open
Purpose: To investigate the effect of application of tiotropium bromide and N- acetylcysteine in combination with respiratory training on the treatment of patients with chronic obstructive pulmonary disease (COPD), and the effect of the co…
View article: ACE2 maybe serve as a prognostic biomarker in breast invasive carcinoma
ACE2 maybe serve as a prognostic biomarker in breast invasive carcinoma Open
Background Breast cancer is a frequently occurring malignant tumor in women. Angiotensin‐converting enzyme 2 (ACE2) is widely expressed in most organs; however, the association of ACE2 with prognosis and immune infiltration in breast invas…
View article: Effect of Lycium barbarum polysaccharides on cell signal transduction pathways
Effect of Lycium barbarum polysaccharides on cell signal transduction pathways Open
Lycium barbarum polysaccharide (LBP), is a major active ingredient Lycium barbarum (LB), which exhibits several beneficial effects through NF-κB, PI3K-Akt-mTOR, p38-MAPK, Wnt-β-catenin, PI3K-Akt-GSK-3β, and MyD88 signal pathway, including …
View article: Callispheres® Drug-Eluting Beads Transarterial Chemoembolization Might be an Efficient and Safety Down-Staging Therapy in Unresectable Liver Cancer Patients
Callispheres® Drug-Eluting Beads Transarterial Chemoembolization Might be an Efficient and Safety Down-Staging Therapy in Unresectable Liver Cancer Patients Open
Purpose: The purpose was to explore the effect of drug-eluting beads transarterial chemoembolization (DEB-TACE) on down-staging in unresectable liver cancer patients.Methods: 15 unresectable liver cancer patients received DEB-TACE as a dow…