Yong Cheng
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View article: [Retracted] Characterization of side population cells isolated from the colon cancer cell line SW480
[Retracted] Characterization of side population cells isolated from the colon cancer cell line SW480 Open
View article: Deconvolution of developmental age refines thymic regulatory T cell ontogeny 3047
Deconvolution of developmental age refines thymic regulatory T cell ontogeny 3047 Open
Description Continuous thymic T-cell selection and regulatory T (Treg) cell development challenges studies of their underlying mechanisms in native physiological conditions. Here, we develop a timestamp approach to trace thymic T-cell orig…
View article: Correction: Metformin Attenuates Partial Epithelial-Mesenchymal Transition in Salivary Gland Inflammation Via PI3K/Akt/GSK3β/Snail Signaling Axis
Correction: Metformin Attenuates Partial Epithelial-Mesenchymal Transition in Salivary Gland Inflammation Via PI3K/Akt/GSK3β/Snail Signaling Axis Open
View article: Fea Of The Influence Of Flat Plate On Mandibular Incisors
Fea Of The Influence Of Flat Plate On Mandibular Incisors Open
Aim or purpose: To investigate the impact of bonded fixed flat plate and movable flat plate on mandibular incisors using finite element analysis, providing a theoretical basis for the selection of clinical flat plate appliances. Materials …
View article: Standard nutrient-solution-based fish-tail-water-fertilizer machine: Design, control, and decision
Standard nutrient-solution-based fish-tail-water-fertilizer machine: Design, control, and decision Open
View article: The Internal Logic and Impact Path of Empowering High-Quality Agricultural Development with Digital New Quality Productivity
The Internal Logic and Impact Path of Empowering High-Quality Agricultural Development with Digital New Quality Productivity Open
Against the backdrop of accelerating the construction of a new development pattern and continuously promoting high-quality agricultural development, the organic integration of digital new quality productivity with agricultural development,…
View article: Etiology, Epidemiology, Clinical and Radiographic Characteristics of 153 Mandibular Supernumerary Teeth in Chinese Non-Syndromic Populations
Etiology, Epidemiology, Clinical and Radiographic Characteristics of 153 Mandibular Supernumerary Teeth in Chinese Non-Syndromic Populations Open
Objective: This study aimed to evaluate the etiology, epidemiology, and clinical and radiological characteristics of mandibular supernumerary teeth (ST)in non-syndromic populations, providing a valuable reference for clinical diagnosis and…
View article: Saliva-derived extracellular vesicles: a promising therapeutic approach for salivary gland fibrosis
Saliva-derived extracellular vesicles: a promising therapeutic approach for salivary gland fibrosis Open
Our findings demonstrate that sEV exerts potent anti-fibrotic effects by modulating STAT3 signaling, offering a promising cell-free therapeutic strategy for SG fibrosis. These results highlight the potential of sEV as a natural nanotherapy…
View article: Expert consensus on imaging diagnosis and analysis of early correction of childhood malocclusion
Expert consensus on imaging diagnosis and analysis of early correction of childhood malocclusion Open
View article: Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity
Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity Open
View article: Elucidating the Impact of Different Substituents on Nonlinear Optical Properties: A Computational Investigation of 4-Cyano-4'-Pentylbiphenyl Liquid Crystal Derivatives
Elucidating the Impact of Different Substituents on Nonlinear Optical Properties: A Computational Investigation of 4-Cyano-4'-Pentylbiphenyl Liquid Crystal Derivatives Open
View article: Molecular Characterization and Functional Analysis of Aat and Saa in Lateolabrax Maculatus and Micropterus Salmoides
Molecular Characterization and Functional Analysis of Aat and Saa in Lateolabrax Maculatus and Micropterus Salmoides Open
View article: Characterisation of P2x3 Receptors in Spotted Sea Bass (Lateolabrax Maculatus): P2x3a and P2x3b Mediate Pro-Inflammatory Innate Immune Response
Characterisation of P2x3 Receptors in Spotted Sea Bass (Lateolabrax Maculatus): P2x3a and P2x3b Mediate Pro-Inflammatory Innate Immune Response Open
View article: Short-term and long-term outcomes of lung transplantation from marginal donors: a single-center retrospective study
Short-term and long-term outcomes of lung transplantation from marginal donors: a single-center retrospective study Open
Our findings suggest that marginal donor recipients can expect to have a lower survival rate than standard donor recipients. However, marginal lung transplant recipients could also gain benefit equivalent to that provided by standard donor…
View article: Exploring Large Language Models for Specialist-level Oncology Care
Exploring Large Language Models for Specialist-level Oncology Care Open
Large language models (LLMs) have shown remarkable progress in encoding clinical knowledge and responding to complex medical queries with appropriate clinical reasoning. However, their applicability in subspecialist or complex medical sett…
View article: Oral screening of dental calculus, gingivitis and dental caries through segmentation on intraoral photographic images using deep learning
Oral screening of dental calculus, gingivitis and dental caries through segmentation on intraoral photographic images using deep learning Open
The proposed deep learning system is expected to be used for the detection of two types of oral diseases and dental calculus, and the degree judgment of photographic images from an intraoral camera. This system offers a practical method to…
View article: Mesenchymal stem cell-derived exosomes: a potential cell-free therapy for orthodontic tooth stability management
Mesenchymal stem cell-derived exosomes: a potential cell-free therapy for orthodontic tooth stability management Open
View article: Morphological variation of gubernacular tracts for permanent mandibular canines in eruption: a three-dimensional analysis
Morphological variation of gubernacular tracts for permanent mandibular canines in eruption: a three-dimensional analysis Open
Objectives This study aims to evaluate the morphological features of gubernacular tract (GT) for erupting permanent mandibular canines at different ages from 5 to 9 years old with a three-dimensional (3D) measurement method. Methods The co…
View article: Metformin Attenuates TGF-β1-Induced Fibrosis in Salivary Gland: A Preliminary Study
Metformin Attenuates TGF-β1-Induced Fibrosis in Salivary Gland: A Preliminary Study Open
Fibrosis commonly arises from salivary gland injuries induced by factors such as inflammation, ductal obstruction, radiation, aging, and autoimmunity, leading to glandular atrophy and functional impairment. However, effective treatments fo…
View article: The relationship between coronary artery calcification and bone metabolic markers in maintenance hemodialysis patients
The relationship between coronary artery calcification and bone metabolic markers in maintenance hemodialysis patients Open
Background To study the influencing factors for coronary artery calcification (CAC) in maintenance hemodialysis (MHD) patients and the relationship between CAC and bone metabolism markers and to attempt to find a reliable marker linking va…
View article: Percutaneous Mechanical Thrombectomy for Acute Limb Ischemia With Aorto-iliac Occlusion
Percutaneous Mechanical Thrombectomy for Acute Limb Ischemia With Aorto-iliac Occlusion Open
Background To evaluate the outcomes of percutaneous mechanical thrombectomy (PMT) with Rotarex catheter in patients with acute lower limb ischemia (ALI) caused by aorto-iliac occlusion. Materials and Methods Data of patients with ALI cause…
View article: Bioinformatics Analysis and Functional Verification of ADAMTS9-AS1/AS2 in Lung Adenocarcinoma
Bioinformatics Analysis and Functional Verification of ADAMTS9-AS1/AS2 in Lung Adenocarcinoma Open
Long non-coding RNAs (lncRNAs), as competitive endogenous RNAs (ceRNAs), play a critical role in biological processes of cancer. However, the roles of specific lncRNAs in ceRNA network of lung adenocarcinoma (LUAD) remains largely unclear.…
View article: Plasma Transfusion Promoted Reprogramming CD4 <sup>+</sup> T Lymphocytes Immune Response in Severe Sepsis Mice Model Through Modulating the Exosome Protein Galectin 9
Plasma Transfusion Promoted Reprogramming CD4 <sup>+</sup> T Lymphocytes Immune Response in Severe Sepsis Mice Model Through Modulating the Exosome Protein Galectin 9 Open
Sepsis is a life-threatening disease that results in excessive stimulation of the host’s immune cells. In the animal study, the purpose was to investigate the roles of fresh frozen plasma (FFP) transfusion in shaping the CD4 + T lymphocyte…
View article: Atractylon induces apoptosis and suppresses metastasis in hepatic cancer cells and inhibits growth in vivo
Atractylon induces apoptosis and suppresses metastasis in hepatic cancer cells and inhibits growth in vivo Open
Yang Cheng,1,2 Tianyang Chen,2 Xueli Yang,2 Jianhua Xue,1 Jianjie Chen1,21Department of Liver Disease, Hospital for Infectious Diseases of Pudong District, Shanghai 201299, People’s Republic of China; 2Institute of Liver Disease, Shuguang …
View article: Anatomical basis for the choice of laparoscopic surgery for low rectal cancer through the pelvic imaging data—a cohort study
Anatomical basis for the choice of laparoscopic surgery for low rectal cancer through the pelvic imaging data—a cohort study Open
View article: A case report of neuroendocrine tumor (G3) at lower rectum with liver metastasis
A case report of neuroendocrine tumor (G3) at lower rectum with liver metastasis Open
Neoadjuvant chemotherapy followed by laparoscopic surgery is a new idea for the treatment of rectal neuroendocrine carcinoma with distant metastasis, which offers favorable conditions for saving the anus during the surgery to enhance the p…
View article: Knockdown of a DIS3L2 promoter upstream long noncoding RNA (AC105461.1) enhances colorectal cancer stem cell properties in vitro by down-regulating DIS3L2
Knockdown of a DIS3L2 promoter upstream long noncoding RNA (AC105461.1) enhances colorectal cancer stem cell properties in vitro by down-regulating DIS3L2 Open
A large number of studies have identified plentiful long noncoding RNAs (lncRNAs) associated with the development of multiple cancers. Some lncRNAs have also been found to be strongly linked with stem cell properties such as pluripotency a…
View article: HMMR antisense RNA 1, a novel long noncoding RNA, regulates the progression of basal-like breast cancer cells
HMMR antisense RNA 1, a novel long noncoding RNA, regulates the progression of basal-like breast cancer cells Open
Recently, accumulating evidence has suggested that long noncoding RNAs (lncRNAs) play crucial roles in carcinogenesis and cancer progression. Hyaluronan-mediated motility receptor (HMMR) is an essential cancer-related gene in basal-like br…
View article: <scp>HCV</scp>‐induced miR146a controls <scp>SOCS</scp>1/<scp>STAT</scp>3 and cytokine expression in monocytes to promote regulatory T‐cell development
<span>HCV</span>‐induced miR146a controls <span>SOCS</span>1/<span>STAT</span>3 and cytokine expression in monocytes to promote regulatory T‐cell development Open
Summary Host innate and adaptive immune responses must be tightly regulated by an intricate balance between positive and negative signals to ensure their appropriate onset and termination while fighting pathogens and avoiding autoimmunity;…
View article: Micro<scp>RNA</scp>‐155 regulates interferon‐<i>γ</i> production in natural killer cells via <scp>T</scp>im‐3 signalling in chronic hepatitis <scp>C</scp> virus infection
Micro<span>RNA</span>‐155 regulates interferon‐<i>γ</i> production in natural killer cells via <span>T</span>im‐3 signalling in chronic hepatitis <span>C</span> virus infection Open
Summary Host immune responses must be tightly regulated by an intricate balance between positive and negative signals while fighting pathogens; persistent pathogens may usurp these regulatory mechanisms to dampen host immunity to facilitat…