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View article: Exploring hypoxia-related genes in spinal cord injury: a pathway to new therapeutic targets
Exploring hypoxia-related genes in spinal cord injury: a pathway to new therapeutic targets Open
Introduction Spinal cord injury (SCI) remains a debilitating condition with limited therapeutic options. Exploring hypoxia-related genes in SCI may reveal potential therapeutic targets and improve our understanding of its pathogenesis. Met…
View article: Normal Tissue Complication Probability Modelling and Predicting for Carbon-Ion Radiotherapy-Induced Severe Esophageal and Tracheobronchial Injuries in Locally Advanced Non-Small Cell Cancer
Normal Tissue Complication Probability Modelling and Predicting for Carbon-Ion Radiotherapy-Induced Severe Esophageal and Tracheobronchial Injuries in Locally Advanced Non-Small Cell Cancer Open
View article: Bone matching versus tumor matching in image-guided carbon ion radiotherapy for locally advanced non-small cell lung cancer
Bone matching versus tumor matching in image-guided carbon ion radiotherapy for locally advanced non-small cell lung cancer Open
View article: Analysis of the resonant converter for multi-terminal collection of DC offshore wind farms
Analysis of the resonant converter for multi-terminal collection of DC offshore wind farms Open
With the rapid development of power electronics technology, the offshore wind power system using DC collection and DC transmission is the best solution to increasing offshore distance. Resonant converters achieving soft switching have beco…
View article: Analysis of three-phase single-stage AC/DC LLC resonant converter
Analysis of three-phase single-stage AC/DC LLC resonant converter Open
Single-stage resonant converters in AC/DC power conversion have been researched widely due to their high efficiency, low size, and low cost. However, the ripples are unavoidable because of the single-stage structure. A three-phase single-s…
View article: DEFINITIVE CARBON ION RADIOTHERAPY FOR TRACHEOBRONCHIAL ADENOID CYSTIC CARCINOMA: UPDATED FOLLOW-UP DATA
DEFINITIVE CARBON ION RADIOTHERAPY FOR TRACHEOBRONCHIAL ADENOID CYSTIC CARCINOMA: UPDATED FOLLOW-UP DATA Open
View article: EFFECT OF DOSE-AVERAGED LINEAR ENERGY TRANSFER ON TUMOR LOCAL CONTROL FOR CARBON-ION RADIOTHERAPY IN LOCALLY ADVANCED NON-SMALL-CELL LUNG CANCER
EFFECT OF DOSE-AVERAGED LINEAR ENERGY TRANSFER ON TUMOR LOCAL CONTROL FOR CARBON-ION RADIOTHERAPY IN LOCALLY ADVANCED NON-SMALL-CELL LUNG CANCER Open
View article: Hypoxia predicts favorable response to carbon ion radiotherapy in non-small cell lung cancer (NSCLC) defined by 18F-FMISO positron emission tomography/computed tomography (PET/CT) imaging
Hypoxia predicts favorable response to carbon ion radiotherapy in non-small cell lung cancer (NSCLC) defined by 18F-FMISO positron emission tomography/computed tomography (PET/CT) imaging Open
A higher degree of tumor hypoxia may be associated with a better IR to CIRT. ΔTMR could predict early treatment response after CIRT.
View article: Dose-Averaged Linear Energy Transfer within the Gross Tumor Volume of Non-Small-Cell Lung Cancer Affects the Local Control in Carbon-Ion Radiotherapy
Dose-Averaged Linear Energy Transfer within the Gross Tumor Volume of Non-Small-Cell Lung Cancer Affects the Local Control in Carbon-Ion Radiotherapy Open
View article: Intensity-modulated proton and carbon-ion radiotherapy using a fixed-beam system for locally advanced lung cancer: dosimetric comparison with x-ray radiotherapy and normal tissue complication probability (NTCP) evaluation
Intensity-modulated proton and carbon-ion radiotherapy using a fixed-beam system for locally advanced lung cancer: dosimetric comparison with x-ray radiotherapy and normal tissue complication probability (NTCP) evaluation Open
Objective . To assess the dosimetric consequences and the normal tissue complication probability (NTCP) for the organs at risk (OARs) in intensity-modulated particle radiotherapy of proton (IMPT) and carbon-ion (IMCT) using a fixed-beam de…
View article: Dosimetric rationale and preliminary experience in proton plus carbon-ion radiotherapy for esophageal carcinoma: a retrospective analysis
Dosimetric rationale and preliminary experience in proton plus carbon-ion radiotherapy for esophageal carcinoma: a retrospective analysis Open
Background Concurrent chemoradiotherapy has been standard of care for unresectable esophageal carcinoma. There were no reports on proton radiotherapy (PRT) plus carbon-ion radiotherapy (CIRT) with pencil beam scanning (PBS) for esophageal …
View article: Progress in the clinical application of constraint-induced therapy following stroke since 2014
Progress in the clinical application of constraint-induced therapy following stroke since 2014 Open
Stroke is a group of cerebrovascular diseases with high prevalence and mortality rate. Stroke can induce many impairments, including motor and cognitive dysfunction, aphasia/dysarthria, dysphagia, and mood disorders, which may reduce the q…
View article: Advances in the clinical application of orthotic devices for stroke and spinal cord injury since 2013
Advances in the clinical application of orthotic devices for stroke and spinal cord injury since 2013 Open
Stroke and spinal cord injury are common neurological disorders that can cause various dysfunctions. Motor dysfunction is a common dysfunction that easily leads to complications such as joint stiffness and muscle contracture and markedly i…
View article: Dual trace gas detection using a compact two-channel multipass cell with dense and line spot patterns
Dual trace gas detection using a compact two-channel multipass cell with dense and line spot patterns Open
View article: <scp>METTL3</scp>‐mediated <scp>m6A mRNA</scp> contributes to the resistance of carbon‐ion radiotherapy in non‐small‐cell lung cancer
<span>METTL3</span>‐mediated <span>m6A mRNA</span> contributes to the resistance of carbon‐ion radiotherapy in non‐small‐cell lung cancer Open
Lung cancer is one of the leading causes of death among cancer patients worldwide. Carbon‐ion radiotherapy is a radical nonsurgical treatment with high local control rates and no serious adverse events. N6‐methyladenosine (m6A) modificatio…
View article: Adaptive carbon ion radiotherapy for locally advanced non‐small cell lung cancer: Organ‐sparing potential and target coverage
Adaptive carbon ion radiotherapy for locally advanced non‐small cell lung cancer: Organ‐sparing potential and target coverage Open
Background The dose distribution of carbon ion radiotherapy (CIRT) for locally advanced non‐small cell lung cancer (LANSCLC) is highly sensitive to anatomical changes. Purpose To demonstrate the dosimetric benefits of adaptive CIRT for LAN…
View article: Transcriptome Profiling Reveals Novel Radiosensitivity Predictors by Integrating Molecular Subtype and Radiosensitivity Signature in Triple-Negative Breast Cancer
Transcriptome Profiling Reveals Novel Radiosensitivity Predictors by Integrating Molecular Subtype and Radiosensitivity Signature in Triple-Negative Breast Cancer Open
View article: Preliminary Safety and Efficacy of Proton Plus Carbon-Ion Radiotherapy With Concurrent Chemotherapy in Limited-Stage Small Cell Lung Cancer
Preliminary Safety and Efficacy of Proton Plus Carbon-Ion Radiotherapy With Concurrent Chemotherapy in Limited-Stage Small Cell Lung Cancer Open
Objectives This study aimed to investigate the tolerance and effect of proton plus carbon-ion radiotherapy with concurrent chemotherapy in limited-stage small cell lung cancer using the pencil beam scanning technique. Materials and Methods…
View article: Definitive carbon ion radiotherapy for tracheobronchial adenoid cystic carcinoma: a preliminary report
Definitive carbon ion radiotherapy for tracheobronchial adenoid cystic carcinoma: a preliminary report Open
Background Tracheobronchial adenoid cystic carcinoma (TACC) is a rare tumour. About one-third of patients miss their chance of surgery or complete resection as it is mostly detected in the advanced stage; hence, photon radiotherapy (RT) is…
View article: RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer
RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer Open
Background The DNA damage and repair pathway is considered a promising target for developing strategies against cancer. RAD51, also known as RECA, is a recombinase that performs the critical step in homologous recombination. RAD51 has rece…
View article: Early stage non-small cell lung cancer treated with pencil beam scanning particle therapy: retrospective analysis of early results on safety and efficacy
Early stage non-small cell lung cancer treated with pencil beam scanning particle therapy: retrospective analysis of early results on safety and efficacy Open
ISRCTN, ISRCTN78973763. Registered 14 August 2018- Retrospectively registered, http://www.isrctn.com/ISRCTN78973763 .
View article: Estrogen Receptor Mediates the Radiosensitivity of Triple-Negative Breast Cancer Cells
Estrogen Receptor Mediates the Radiosensitivity of Triple-Negative Breast Cancer Cells Open
BACKGROUND This study aimed to evaluate differences in the radiosensitivities of triple-negative breast cancer (TNBC) and luminal-type breast cancer cells and to investigate the effects of estrogen receptor (ER) expression on the biologica…
View article: Improved Survival in Patients with Resected Pancreatic Carcinoma Using Postoperative Intensity-Modulated Radiotherapy and Regional Intra-Arterial Infusion Chemotherapy
Improved Survival in Patients with Resected Pancreatic Carcinoma Using Postoperative Intensity-Modulated Radiotherapy and Regional Intra-Arterial Infusion Chemotherapy Open
BACKGROUND We assessed the role of adjuvant intensity-modulated radiotherapy (IMRT) in combination with chemotherapy for pancreatic carcinomas after curative resection and identified prognostic factors related to pancreatic carcinoma after…