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View article: Proteomic-based identification of novel EV-derived protein antibodies biomarkers for melioidosis diagnosis
Proteomic-based identification of novel EV-derived protein antibodies biomarkers for melioidosis diagnosis Open
Melioidosis, caused by Burkholderia pseudomallei ( Bp ), is a life-threatening disease characterized by diverse clinical manifestations and limited diagnostic capabilities. Extracellular vesicles (EVs) have emerged as critical carriers of …
View article: The genetic diversity and evolution analysis of the Hainan melioidosis outbreak strains
The genetic diversity and evolution analysis of the Hainan melioidosis outbreak strains Open
Melioidosis is a zoonotic disease, with its outbreaks being rare and indicative of an unusual concurrence of extreme climate and natural environmental factors. An outbreak of melioidosis cases emerged in Hainan following Typhoon "Dianmu" f…
View article: Synchronous detection of <i>Burkholderia pseudomallei</i> and its ceftazidime resistance mutation based on RNase-HII hydrolysis combined with lateral flow strip assay
Synchronous detection of <i>Burkholderia pseudomallei</i> and its ceftazidime resistance mutation based on RNase-HII hydrolysis combined with lateral flow strip assay Open
Melioidosis is a severe and often fatal infectious disease caused by Burkholderia pseudomallei , which poses significant challenges due to its high mortality rate and frequent misdiagnosis. To effectively treat infected patients, especiall…
View article: A novel lytic phage potentially effective for phage therapy against Burkholderia pseudomallei in the tropics
A novel lytic phage potentially effective for phage therapy against Burkholderia pseudomallei in the tropics Open
Background Burkholderia pseudomallei is a tropical pathogen that causes melioidosis. Its intrinsic drug-resistance is a leading cause of treatment failure, and the few available antibiotics require prolonged use to be effective. This study…
View article: Multifunctional MOF-based Electrochemiluminescent Nanocubes for an Ultrasensitive Biosensing Strategy of B. Pseudomallei Determination Coupled With 3D Magnetic Walking Nanomachine
Multifunctional MOF-based Electrochemiluminescent Nanocubes for an Ultrasensitive Biosensing Strategy of B. Pseudomallei Determination Coupled With 3D Magnetic Walking Nanomachine Open
Burkholderia pseudomallei ( B. pseudomallei ) can cause melioidosis that is usually fatal. A reliable and rapid detection method is greatly needed for disease surveillance and diagnosis. Herein, an ultrasensitive electrochemiluminescence (…