Nir Kugelman
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View article: Polycystic Ovarian Morphology and Chronic Morbidity and Mortality in PCOS
Polycystic Ovarian Morphology and Chronic Morbidity and Mortality in PCOS Open
Importance Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder associated with insulin resistance and cardiovascular risk. The long-term association of ovarian morphology subtypes with long-term morbidity and mortality remai…
View article: Pregnancy and neonatal outcomes in women with arcuate uterus: a population-based cohort study of over 3.8 million women
Pregnancy and neonatal outcomes in women with arcuate uterus: a population-based cohort study of over 3.8 million women Open
Background Congenital uterine anomalies are associated with adverse reproductive outcomes, yet the impact of the arcuate uterus remains unclear due to limited sample sizes and inconsistent findings in previous studies. We utilized a large …
View article: The effect of breastfeeding on treatment outcomes in in-vitro fertilization frozen embryo transfer cycles
The effect of breastfeeding on treatment outcomes in in-vitro fertilization frozen embryo transfer cycles Open
Breastfeeding during an FET cycle was not associated with treatment outcomes, including PR,CPR, or LBR, providing cautious reassurance to physicians and patients.
View article: Evaluating the impact of repeated ovarian stimulation cycles on follicle development in patients with suboptimal response
Evaluating the impact of repeated ovarian stimulation cycles on follicle development in patients with suboptimal response Open
Objective To assess if repeat ovarian stimulation improves follicle development after a canceled suboptimal cycle. Methods This retrospective cohort study included 162 patients who underwent two consecutive ovarian stimulation cycles betwe…
View article: P-658 A 37-year prospective study of polycystic ovary syndrome (PCOS) patients: impact of free testosterone levels in youth on long-term morbidity and mortality
P-658 A 37-year prospective study of polycystic ovary syndrome (PCOS) patients: impact of free testosterone levels in youth on long-term morbidity and mortality Open
Study question Does free testosterone level at young age, influence long-term morbidity and mortality in PCOS patients? Summary answer PCOS patients with higher youth free testosterone show increased psychiatric disorders and hypothyroidis…
View article: P-679 Does low birth weight have an effect on ovarian reserve?
P-679 Does low birth weight have an effect on ovarian reserve? Open
Study question Do small for gestational age (SGA) female newborns have lower AMH levels compared to appropriate for gestational age (AGA) female newborns? Summary answer No differences were found between neonatal AMH levels of the SGA and …
View article: O-128 A 37-year prospective study of polycystic ovary syndrome patients: impact of body mass index at enrolment on long-term morbidity and mortality
O-128 A 37-year prospective study of polycystic ovary syndrome patients: impact of body mass index at enrolment on long-term morbidity and mortality Open
Study question Does weight classification (lean, overweight, obese) in polycystic ovary syndrome (PCOS) patients affect long-term morbidity and mortality? Summary answer Young obese-PCOS exhibited higher risks for chronic conditions later …
View article: Pregnancy and Neonatal Outcomes in Women with Arcuate Uterus: A Population-Based Cohort Study of Over 3.8 Million Women
Pregnancy and Neonatal Outcomes in Women with Arcuate Uterus: A Population-Based Cohort Study of Over 3.8 Million Women Open
Background: Congenital uterine anomalies are associated with adverse reproductive outcomes, yet the impact of the arcuate uterus remains unclear due to limited sample sizes and inconsistent findings in previous studies. We utilized a large…
View article: Basal serum luteinizing hormone, total testosterone, and free testosterone levels do not impact IVF outcomes in patients with polycystic ovary syndrome
Basal serum luteinizing hormone, total testosterone, and free testosterone levels do not impact IVF outcomes in patients with polycystic ovary syndrome Open
Basal serum levels of LH, TT, and FT did not significantly affect IVF outcomes in patients with PCOS using GnRH antagonist, freeze-all protocols.
View article: Impact of stimulation with luteinizing hormone activity on IVF outcomes in patients with polycystic ovary syndrome
Impact of stimulation with luteinizing hormone activity on IVF outcomes in patients with polycystic ovary syndrome Open
LH supplementation in PCOS patients undergoing GnRH antagonist IVF protocols may impair cumulative live birth rates, despite lowering FSH requirement and reducing IVF cycle length. These results highlight the complex role of LH in IVF outc…
View article: Expectant management of tubal pregnancies with human chorionic gonadotropin up to 2000 mIU/mL
Expectant management of tubal pregnancies with human chorionic gonadotropin up to 2000 mIU/mL Open
Objective To describe outcomes of expectant management (EM) versus methotrexate (MTX) treatment in tubal pregnancies with pretreatment human chorionic gonadotropin (hCG) less than 2000 mIU/mL. Methods This retrospective cohort from two ter…
View article: Risk factors for pelvic organ prolapse recurrence following colpocleisis: A meta‐analysis
Risk factors for pelvic organ prolapse recurrence following colpocleisis: A meta‐analysis Open
Background Studies aimed to assess risk factors for pelvic organ prolapse (POP) recurrence following colpocleisis with nonconclusive results. Objective To investigate risk factors for POP recurrence following colpocleisis. Search Strategy …
View article: P-738 Attitude of BRCA1/2 mutation carriers towards fertility preservation, family planning and preimplantation genetic testing (PGT) for the next-generation primary prevention of breast and ovarian cancer
P-738 Attitude of BRCA1/2 mutation carriers towards fertility preservation, family planning and preimplantation genetic testing (PGT) for the next-generation primary prevention of breast and ovarian cancer Open
Study question What is BRCA1/2 mutation carriers' attitude toward preimplantation genetic testing (PGT) in attempt to prevent their offspring burden that comes with a known mutation status? Summary answer Less than ten percent of BRCA1/2 m…
View article: Safety of COVID‐19 vaccination in pregnant women: A study of the adverse perinatal outcomes
Safety of COVID‐19 vaccination in pregnant women: A study of the adverse perinatal outcomes Open
Objective To compare adverse perinatal outcome among coronavirus disease 2019 (COVID‐19)–vaccinated and –unvaccinated pregnant women. Method Retrospective equivalence cohort study comparing 930 women who received at least one BNT162b2 (Pfi…
View article: P-062 Morphokinetic embryo division timings and top-quality cleavage and blastocyst rates are unaffected by sperm quality
P-062 Morphokinetic embryo division timings and top-quality cleavage and blastocyst rates are unaffected by sperm quality Open
Study question Does testicular extracted sperm affect embryo morphokinetics and the rate of top-quality cleavage and blastocyst embryos. Summary answer Sperm origin, whether ejaculated normal sperm or testicular extracted sperm, was not fo…
View article: Laboratory and imaging findings of necrotizing otitis externa are associated with pathogen type and disease outcome: A retrospective analysis.
Laboratory and imaging findings of necrotizing otitis externa are associated with pathogen type and disease outcome: A retrospective analysis. Open
Objective To examine associations of laboratory and imaging data with diagnostic parameters of necrotizing otitis externa (NOE) and its severity, and to compare between bacterial and fungal infections. Methods Records of patients diagnosed…
View article: Maternal and Neonatal SARS-CoV-2 Immunoglobulin G Antibody Levels at Delivery After Receipt of the BNT162b2 Messenger RNA COVID-19 Vaccine During the Second Trimester of Pregnancy
Maternal and Neonatal SARS-CoV-2 Immunoglobulin G Antibody Levels at Delivery After Receipt of the BNT162b2 Messenger RNA COVID-19 Vaccine During the Second Trimester of Pregnancy Open
In this cohort study, receipt of the BNT162b2 mRNA COVID-19 vaccine during the second trimester of pregnancy was associated with maternal and neonatal humoral responses, as reflected in maternal and neonatal SARS-CoV-2 IgG antibody levels …
View article: 226 Clearance of HPV after conization of cervical cancer and adenocarcinoma in situ correlates with absence of cancer
226 Clearance of HPV after conization of cervical cancer and adenocarcinoma in situ correlates with absence of cancer Open
Introduction/Background* About 40% of CC are in women under age 40 years, for whom fertility-sparing treatment might be very important and should always be considered. More than half the patients who undergo radical surgery (trachelectomy …
View article: 220 Enhanced recovery after surgery is feasible, beneficial and should be the standard in major gynecological surgeries
220 Enhanced recovery after surgery is feasible, beneficial and should be the standard in major gynecological surgeries Open
Introduction/Background* Enhanced recovery after surgery (ERAS) protocols are evidence-based protocols designed to standardize medical care, improve outcomes, and lower health care costs. Our objective was to evaluate the implementation of…
View article: 218 Worse Prognosis of Human Papillomavirus Negative Compared to Human Papillomavirus Positive Cervical Cancer
218 Worse Prognosis of Human Papillomavirus Negative Compared to Human Papillomavirus Positive Cervical Cancer Open
Introduction/Background* To evaluate the prevalence and prognosis of human papillomavirus (HPV)-negative cervical cancer (CC), and compare these to data for HPV-positive CC. Methodology This retrospective cohort study compared between HPV-…