Nirav R. Shah
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View article: Statistical evaluation of open source DEMs for accurate watershed delineation in sustainable river basin management
Statistical evaluation of open source DEMs for accurate watershed delineation in sustainable river basin management Open
Accurate Digital Elevation Models (DEMs) are critical for understanding river and catchment geomorphology, which in turn supports sustainable water management decisions such as flood mitigation and land-use planning. This study evaluates t…
View article: Shaping the Future of Senior Living: Technology-Driven and Person-Centric Approaches
Shaping the Future of Senior Living: Technology-Driven and Person-Centric Approaches Open
By 2040, more than 80 million Americans will be aged ≥65, yet contemporary senior living communities still operate on a hospitality-first model developed for healthier cohorts three decades ago. This commentary argues that the next generat…
View article: AI in Early Diagnosis of Chronic Diseases
AI in Early Diagnosis of Chronic Diseases Open
- Chronic diseases (non-communicable diseases) such as diabetes, cardiovascular disease, cancer, and neurological disorders impose a tremendous global health burden, accounting for over 40 million deaths annually (≈71% of all deaths). Earl…
View article: Complete Resolution of Atypical Paraneoplastic Pemphigus Following Treatment With Dupilumab
Complete Resolution of Atypical Paraneoplastic Pemphigus Following Treatment With Dupilumab Open
View article: Gamified Self-Regulation and AI Risk Detection in Student Mental Health: Pilot Study Results
Gamified Self-Regulation and AI Risk Detection in Student Mental Health: Pilot Study Results Open
View article: AI-Augmented Communication Improves HIV PrEP Initiation and Persistence in High-Risk Populations 
AI-Augmented Communication Improves HIV PrEP Initiation and Persistence in High-Risk Populations Open
View article: Testing and Evaluation of Health Care Applications of Large Language Models
Testing and Evaluation of Health Care Applications of Large Language Models Open
Importance Large language models (LLMs) can assist in various health care activities, but current evaluation approaches may not adequately identify the most useful application areas. Objective To summarize existing evaluations of LLMs in h…
View article: Beyond Brick and Mortar: The Rise of Street Medicine
Beyond Brick and Mortar: The Rise of Street Medicine Open
View article: We Need to Rethink Nursing Homes
We Need to Rethink Nursing Homes Open
View article: Comparison of Patch Testing Results of White and Black Patients.
Comparison of Patch Testing Results of White and Black Patients. Open
Patch testing is the standard diagnostic test used for patients presenting with symptoms of allergic contact dermatitis. The grading of patch test results classically varies from 1 to 3. The assessment of these results begins with a visual…
View article: A Systematic Review of Testing and Evaluation of Healthcare Applications of Large Language Models (LLMs)
A Systematic Review of Testing and Evaluation of Healthcare Applications of Large Language Models (LLMs) Open
1 Abstract Importance Large Language Models (LLMs) can assist in a wide range of healthcare-related activities. Current approaches to evaluating LLMs make it difficult to identify the most impactful LLM application areas. Objective To summ…
View article: Association between maternal employment status and presence of children with major congenital anomalies in Denmark
Association between maternal employment status and presence of children with major congenital anomalies in Denmark Open
View article: Decentralizing Health Care: History and Opportunities of Web3
Decentralizing Health Care: History and Opportunities of Web3 Open
This paper explores the relationship between the development of the internet and health care, highlighting their parallel growth and mutual influence. It delves into the transition from the early, static days of Web 1.0, akin to siloed phy…
View article: Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models
Population pharmacokinetics and humanized dosage regimens matching the peak, area, trough, and range of amikacin plasma concentrations in immune-competent murine bloodstream and lung infection models Open
Amikacin is an FDA-approved aminoglycoside antibiotic that is commonly used. However, validated dosage regimens that achieve clinically relevant exposure profiles in mice are lacking. We aimed to design and validate humanized dosage regime…
View article: Leveraging Landsat Imagery and Support Vector Machine for Land Use/Land Cover Change Detection: A Case Study of the Panam River Watershed
Leveraging Landsat Imagery and Support Vector Machine for Land Use/Land Cover Change Detection: A Case Study of the Panam River Watershed Open
This study investigates land cover/land use (LULC) changes within the Panam River Watershed between 2011 and 2023. Leveraging freely available Landsat imagery and geospatial technologies like remote sensing and GIS, the research analyzes f…
View article: Decentralizing Health Care: History and Opportunities of Web3 (Preprint)
Decentralizing Health Care: History and Opportunities of Web3 (Preprint) Open
UNSTRUCTURED This paper explores the relationship between the development of the internet and health care, highlighting their parallel growth and mutual influence. It delves into the transition from the early, static days of Web 1.0, akin…
View article: Development and Assessment of an Artificial Intelligence-Based Tool for Ptosis Measurement in Adult Myasthenia Gravis Patients Using Selfie Video Clips Recorded on Smartphones
Development and Assessment of an Artificial Intelligence-Based Tool for Ptosis Measurement in Adult Myasthenia Gravis Patients Using Selfie Video Clips Recorded on Smartphones Open
Introduction: Myasthenia gravis (MG) is a rare autoimmune disease characterized by muscle weakness and fatigue. Ptosis (eyelid drooping) occurs due to fatigue of the muscles for eyelid elevation and is one symptom widely used by patients a…
View article: Unpaid Family Caregiving—The Next Frontier of Gender Equity in a Postpandemic Future
Unpaid Family Caregiving—The Next Frontier of Gender Equity in a Postpandemic Future Open
This Viewpoint discusses how the COVID-19 pandemic has spotlighted the critical role of unpaid family caregiving.
View article: Improving value for underserved populations with a community-based intervention: a retrospective cohort study
Improving value for underserved populations with a community-based intervention: a retrospective cohort study Open
Background Healthcare inequity drives high costs, worse outcomes and is heavily influenced by social determinants of health (SDOH). Addressing health behaviors and SDOH through a culturally competent community-based exposure may be effecti…
View article: Corrigendum: Personalized digital intervention for depression based on social rhythm principles adds significantly to outpatient treatment
Corrigendum: Personalized digital intervention for depression based on social rhythm principles adds significantly to outpatient treatment Open
[This corrects the article DOI: 10.3389/fdgth.2022.870522.].
View article: Streamlining Test-to-Treat: A Novel Care Delivery Model for Covid-19 Oral Antiviral Access to Close the Equity Divide in Los Angeles County
Streamlining Test-to-Treat: A Novel Care Delivery Model for Covid-19 Oral Antiviral Access to Close the Equity Divide in Los Angeles County Open
The Los Angeles County Department of Public Health, in collaboration with Healthvana, a well-established private-sector partner, was able to quickly stand up a program to target patients in socially and economically disadvantaged communiti…
View article: Racial Disparities in Inpatient Palliative Care Consultation Among Frail Older Patients Undergoing High-Risk Elective Surgical Procedures in the United States: A Cross-Sectional Study of the National Inpatient Sample
Racial Disparities in Inpatient Palliative Care Consultation Among Frail Older Patients Undergoing High-Risk Elective Surgical Procedures in the United States: A Cross-Sectional Study of the National Inpatient Sample Open
View article: Personalized digital intervention for depression based on social rhythm principles adds significantly to outpatient treatment
Personalized digital intervention for depression based on social rhythm principles adds significantly to outpatient treatment Open
We conducted a 16-week randomized controlled trial in psychiatric outpatients with a lifetime diagnosis of a mood and/or anxiety disorder to measure the impact of a first-of-its-kind precision digital intervention software solution based o…
View article: Graphisches Inhaltsverzeichnis: Angew. Chem. 30/2022
Graphisches Inhaltsverzeichnis: Angew. Chem. 30/2022 Open
in ihrem Forschungsartikel (e202202078) berichten, macht Sylite inhibitorische Synapsen in Neuronenkulturen und in Hirngewebe sichtbar und kann flexibel für die Weitfeld-und konfokale 3D-Darstellung von Synapsen, für die Kartierung inhibit…
View article: A Brief History of Exposure Notification During the COVID-19 Pandemic in the United States, 2020-2021
A Brief History of Exposure Notification During the COVID-19 Pandemic in the United States, 2020-2021 Open
The swift global spread of COVID-19 prompted public health authorities to explore digital technologies to aid in contact tracing for infection control. Exposure notification, a mobile device–based technology that notifies individuals of po…
View article: Precision Digital Intervention for Depression Based on Social Rhythm Principles Adds Significantly to Outpatient Treatment
Precision Digital Intervention for Depression Based on Social Rhythm Principles Adds Significantly to Outpatient Treatment Open
We conducted a 16-week randomized controlled trial in psychiatric outpatients with a lifetime diagnosis of a mood and/or anxiety disorder to measure the impact of a first of its kind precision digital intervention based on social rhythm re…
View article: Mothers of children with major congenital anomalies have increased health care utilization over a 20-year post-birth time horizon
Mothers of children with major congenital anomalies have increased health care utilization over a 20-year post-birth time horizon Open
Objective This population-based, matched cohort study aimed to evaluate utilization of health care services by mothers of children with major congenital anomalies (MCAs), compared to mothers of children without MCAs over a 20-year post-bir…
View article: Empowering clinical research in a decentralized world
Empowering clinical research in a decentralized world Open
View article: Predicting Environmental Allergies from Real World Data Through a Mobile Study Platform
Predicting Environmental Allergies from Real World Data Through a Mobile Study Platform Open
Chethan Sarabu,1,2 Sandra Steyaert,1 Nirav R Shah1– 3 1Sharecare Inc., Atlanta, GA, USA; 2Stanford Medicine, Palo Alto, CA, USA; 3Clinical Excellence Research Center, Stanford, CA, USACorrespondence: Chethan SarabuSharecare Inc., 255 East …
View article: Combating Multidrug‐Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling
Combating Multidrug‐Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling Open
Multidrug‐resistant bacteria are causing a serious global health crisis. A dramatic decline in antibiotic discovery and development investment by pharmaceutical industry over the last decades has slowed the adoption of new technologies. It…