Nirupama Banerjee
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View article: Study of antibiotic consumption using a novel unit among indoor pediatric patients in India
Study of antibiotic consumption using a novel unit among indoor pediatric patients in India Open
Unlike adult population, the Defined Daily Dose/100 Patient Days (DDD/100 PD) cannot be used as a standard unit in pediatric studies. In this study, we measured antibiotic consumption using standard unit’s used- DDD/100 PD and DDD per 1000…
View article: Identification of genes associated with persistence in Mycobacterium smegmatis
Identification of genes associated with persistence in Mycobacterium smegmatis Open
The prevalence of bacterial persisters is related to their phenotypic diversity and is responsible for the relapse of chronic infections. Tolerance to antibiotic therapy is the hallmark of bacterial persistence. In this study, we have scre…
View article: Adjuvant Potential of Poly-α- <scp>l</scp> -Glutamine from the Cell Wall of Mycobacterium tuberculosis
Adjuvant Potential of Poly-α- <span>l</span> -Glutamine from the Cell Wall of Mycobacterium tuberculosis Open
Novel adjuvants are in demand for improving the efficacy of human vaccines. The immunomodulatory properties of Mycobacterium tuberculosis cell wall components have been highlighted in the formulation of complete Freund's adjuvant (CFA).
View article: The Chromosomal parDE2 Toxin–Antitoxin System of Mycobacterium tuberculosis H37Rv: Genetic and Functional Characterization
The Chromosomal parDE2 Toxin–Antitoxin System of Mycobacterium tuberculosis H37Rv: Genetic and Functional Characterization Open
Mycobacterium tuberculosis H37Rv escapes host-generated stresses by entering a dormant persistent state. Activation of toxin-antitoxin modules is one of the mechanisms known to trigger such a state with low metabolic activity. M. tuberculo…