Nisha Sharma
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View article: Vacuum-assisted biopsy in the era of low-risk ductal carcinoma in situ active monitoring: real world data and implications
Vacuum-assisted biopsy in the era of low-risk ductal carcinoma in situ active monitoring: real world data and implications Open
Background The short-term oncological safe of active monitoring for ductal carcinoma in situ (DCIS) with low risk (LR-DCIS) of progression to invasive cancers (IC) has been demonstrated. This study evaluates vacuum assisted biopsy (VAB) as…
View article: nmrXiv enhances the utility of NMR spectroscopic data of natural products
nmrXiv enhances the utility of NMR spectroscopic data of natural products Open
View article: A COMPARISON OF PHYSIOLOGICAL CHANGES INDUCED BY PRONE POSITION OVER WILSON’S FRAME AND HORIZONTAL BOLSTERS IN LUMBAR SPINE SURGERY – A RANDOMIZED PROSPECTIVE STUDY
A COMPARISON OF PHYSIOLOGICAL CHANGES INDUCED BY PRONE POSITION OVER WILSON’S FRAME AND HORIZONTAL BOLSTERS IN LUMBAR SPINE SURGERY – A RANDOMIZED PROSPECTIVE STUDY Open
View article: Vacuum-assisted breast biopsy compared to core needle biopsy: Results of a Systematic Review and Meta-Analysis
Vacuum-assisted breast biopsy compared to core needle biopsy: Results of a Systematic Review and Meta-Analysis Open
View article: Assessment of Rhinitis Control Assessment Test Score after Vitamin D Supplementation along with Standard Regimen in Patients of Allergic Rhinitis – A Prospective Randomized Control Trial
Assessment of Rhinitis Control Assessment Test Score after Vitamin D Supplementation along with Standard Regimen in Patients of Allergic Rhinitis – A Prospective Randomized Control Trial Open
Background: Allergic rhinitis (AR) affects 10%–20% of the global population, significantly impacting daily activities and quality of life. It has varied clinical presentations including sneezing, nasal discharge, and watering and itching i…
View article: Comparison of supplemental breast cancer imaging techniques—interim results from the BRAID randomised controlled trial
Comparison of supplemental breast cancer imaging techniques—interim results from the BRAID randomised controlled trial Open
Cancer Research UK, GE Healthcare, and Bayer Healthcare.
View article: Assessing artificial intelligence in breast screening with stratified results on 306 839 mammograms across geographic regions, age, breast density and ethnicity: A Retrospective Investigation Evaluating Screening (ARIES) study
Assessing artificial intelligence in breast screening with stratified results on 306 839 mammograms across geographic regions, age, breast density and ethnicity: A Retrospective Investigation Evaluating Screening (ARIES) study Open
Objectives Evaluate an Artificial Intelligence (AI) system in breast screening through stratified results across age, breast density, ethnicity and screening centres, from different UK regions. Methods A large-scale retrospective study eva…
View article: SMALL: open surgery versus minimally invasive vacuum-assisted excision for small screen-detected breast cancer—protocol for a phase III randomised multicentre trial
SMALL: open surgery versus minimally invasive vacuum-assisted excision for small screen-detected breast cancer—protocol for a phase III randomised multicentre trial Open
Introduction Mammographic screening identifies many women with small breast cancers with favourable biological features, which have an excellent prognosis. Some of these may never have become clinically apparent without screening and are c…
View article: Antimicrobial prescription patterns in tertiary care centres in India: a multicentric point prevalence survey
Antimicrobial prescription patterns in tertiary care centres in India: a multicentric point prevalence survey Open
View article: Predicting responses to chemotherapy from nutrition in triple negative breast cancer patients (The PRE-NUTRITIVE Study): protocol for a prospective feasibility study
Predicting responses to chemotherapy from nutrition in triple negative breast cancer patients (The PRE-NUTRITIVE Study): protocol for a prospective feasibility study Open
Background Adherence to the World Cancer Research Fund (WCRF) and American Institute for Cancer Research (AICR) cancer prevention guidelines is linked to lower cancer incidence and improved outcomes. However, the relationship between these…
View article: A novel soluble guanylate cyclase activator, avenciguat, in combination with empagliflozin, protects against renal and hepatic injury in diabetic <i>db/db</i> mice
A novel soluble guanylate cyclase activator, avenciguat, in combination with empagliflozin, protects against renal and hepatic injury in diabetic <i>db/db</i> mice Open
Whether combining an sGC activator with an SGLT2 inhibitor could better control diabetes-associated oxidative stress and NO-cGMP signal deficiency has not yet been explored. Using the type 2 diabetic db/db mouse model, this study underscor…
View article: P215: NOSTRA-Feasibility: Predicting pathological complete response using multiple ultrasound-guided tumour bed core biopsies after neoadjuvant systemic therapy in HER-2 positive ER negative breast cancer
P215: NOSTRA-Feasibility: Predicting pathological complete response using multiple ultrasound-guided tumour bed core biopsies after neoadjuvant systemic therapy in HER-2 positive ER negative breast cancer Open
View article: Enhancing osseointegration in dental implants with topical platelet - rich fibrin
Enhancing osseointegration in dental implants with topical platelet - rich fibrin Open
The impact of platelet-rich fibrin as a topical application on osseointegration in dental implants is of interest. Hence, a medical questionnaire was used to gather information during the initial interview, including details about past and…
View article: COCONUT 2.0: A comprehensive overhaul and curation of the collection of open natural products database
COCONUT 2.0: A comprehensive overhaul and curation of the collection of open natural products database Open
The COCONUT (COlleCtion of Open Natural prodUcTs) database was launched in 2021 as an aggregation of openly available natural product datasets and has been one of the biggest open natural product databases since. Apart from the chemical st…
View article: Diagnostic performance of tomosynthesis plus synthetic mammography versus full‐field digital mammography with or without tomosynthesis in breast cancer screening: A systematic review and meta‐analysis
Diagnostic performance of tomosynthesis plus synthetic mammography versus full‐field digital mammography with or without tomosynthesis in breast cancer screening: A systematic review and meta‐analysis Open
Digital breast tomosynthesis (DBT) with full‐field digital mammography (FFDM) exposes women to a higher radiation dose. A synthetic 2D mammogram (S2D) is a two‐dimensional image constructed from DBT. We aim to evaluate the S2D performance …
View article: COCONUT 2.0: A comprehensive overhaul and curation of the collection of open natural products database
COCONUT 2.0: A comprehensive overhaul and curation of the collection of open natural products database Open
The COCONUT (COlleCtion of Open Natural prodUcTs) database was launched in 2021 as an aggregation of openly available natural product datasets and has been one of the biggest open natural product databases since. Apart from the chemical st…
View article: High prevalence of cagA positive Vac A s1m1 Helicobacter pylori strains isolated from patients suffering from various gastroduodenal diseases in Guwahati, Assam, India
High prevalence of cagA positive Vac A s1m1 Helicobacter pylori strains isolated from patients suffering from various gastroduodenal diseases in Guwahati, Assam, India Open
Aim and Background: Genotyping of H. pylori strains was identified on formalin-fixed paraffin wax-embedded tissue (FFPE) sections and correlated with severity grades of gastric mucosal pathologies in biopsies from upper gastrointestinal (U…
View article: How long does it take to read a mammogram? Investigating the reading time of digital breast tomosynthesis and digital mammography
How long does it take to read a mammogram? Investigating the reading time of digital breast tomosynthesis and digital mammography Open
gov Identifier: NCT03733106.
View article: The relationship between parameters measured using intravoxel incoherent motion and dynamic contrast-enhanced MRI in patients with breast cancer undergoing neoadjuvant chemotherapy: a longitudinal cohort study
The relationship between parameters measured using intravoxel incoherent motion and dynamic contrast-enhanced MRI in patients with breast cancer undergoing neoadjuvant chemotherapy: a longitudinal cohort study Open
Purpose The primary aim of this study was to explore whether intravoxel incoherent motion (IVIM) can offer a contrast-agent-free alternative to dynamic contrast-enhanced (DCE)-MRI for measuring breast tumor perfusion. The secondary aim was…
View article: Vacuum-assisted excision: a safe minimally invasive option for benign phyllodes tumor diagnosis and treatment—a systematic review and meta-analysis
Vacuum-assisted excision: a safe minimally invasive option for benign phyllodes tumor diagnosis and treatment—a systematic review and meta-analysis Open
Synopsis This is a systematic review and meta-analysis comparing surgical excision with percutaneous ultrasound-guided vacuum-assisted excision (US-VAE) for the treatment of benign phyllodes tumor (PT) using local recurrence (LR) as the en…
View article: Carbon Nanotube Field Effect Transistor Technology for Power Reduction
Carbon Nanotube Field Effect Transistor Technology for Power Reduction Open
CMOS is the preferred technology choice for silicon-based high-performance digital circuits.Although silicon-based technology continues to expand and explore materials and models for future technologies.Carbon nanotube field-effect transis…
View article: IT Infrastructure Management: Optimizing Performance, Scalability, and Reliability
IT Infrastructure Management: Optimizing Performance, Scalability, and Reliability Open
This abstract examines the essential elements of IT infrastructure management, focusing on increased performance, scalability, and reliability. In today's dynamic business environment, organizations are increasingly reliant on their IT sys…
View article: Introduction of automated breast ultrasound as an additional screening tool for dense breasts in the UK: a practical approach from the BRAID trial
Introduction of automated breast ultrasound as an additional screening tool for dense breasts in the UK: a practical approach from the BRAID trial Open
Highlights•ABUS is a 3D volume imaging technique for screening dense breasts, with similar diagnostic accuracy as handheld Ultrasound.•Adequate training, systematic quality checks and a learning curve are crucial in improving scans quality…
View article: Minimally invasive treatment of early, good prognosis breast cancer—is this feasible?
Minimally invasive treatment of early, good prognosis breast cancer—is this feasible? Open
Breast cancer screening programmes frequently detect early, good prognosis breast cancers with significant treatment burden for patients, and associated health-cost implications. Emerging evidence suggests a role for minimally invasive tec…
View article: Atypia detected during breast screening and subsequent development of cancer: observational analysis of the Sloane atypia prospective cohort in England
Atypia detected during breast screening and subsequent development of cancer: observational analysis of the Sloane atypia prospective cohort in England Open
Objective To explore how the number and type of breast cancers developed after screen detected atypia compare with the anticipated 11.3 cancers detected per 1000 women screened within one three year screening round in the United Kingdom. D…
View article: Corrigendum to “European guidelines for the diagnosis, treatment and follow-up of breast lesions with uncertain malignant potential (B3 lesions) developed jointly by EUSOMA, EUSOBI, ESP (BWG) and ESSO” [Eur J Surg Oncol 50 (1) (January 2024) 107292]
Corrigendum to “European guidelines for the diagnosis, treatment and follow-up of breast lesions with uncertain malignant potential (B3 lesions) developed jointly by EUSOMA, EUSOBI, ESP (BWG) and ESSO” [Eur J Surg Oncol 50 (1) (January 2024) 107292] Open
The authors would like to point out the following corrections to Figs. 5 and 7 within the article. The legend for Fig. 5 should be:[Formula presented] The citation of Fig. 5 within the text should also be removed from its current position …
View article: Cost-Effectiveness Analysis of Digital Breast Tomosynthesis Added to Synthetic Mammography in Breast Cancer Screening in Brazil
Cost-Effectiveness Analysis of Digital Breast Tomosynthesis Added to Synthetic Mammography in Breast Cancer Screening in Brazil Open
Switching from DM to biennial DBT + s2D was cost effective. Furthermore, reductions in false-positive recall rates should also be considered in decision making.
View article: Heterologous expression of Arabidopsis laccase2, laccase4 and peroxidase52 driven under developing xylem specific promoter DX15 improves saccharification in populus
Heterologous expression of Arabidopsis laccase2, laccase4 and peroxidase52 driven under developing xylem specific promoter DX15 improves saccharification in populus Open
View article: Designing a Dynamic Weighted Stacking Recommendation System
Designing a Dynamic Weighted Stacking Recommendation System Open
To increase accuracy, ensemble approaches have become increasingly popular in designing recommendation systems. More recently, efforts have focused on dynamically integrating base models to improve ensemble performance further. Dynamic int…
View article: Evidence-informed recommendations on managing breast screening atypia: perspectives from an expert panel consensus meeting reviewing results from the Sloane atypia project
Evidence-informed recommendations on managing breast screening atypia: perspectives from an expert panel consensus meeting reviewing results from the Sloane atypia project Open
Evidence-based clinical guidelines are essential to maximize patient benefit and to reduce clinical uncertainty and inconsistency in clinical practice. Gaps in the evidence base can be addressed by data acquired in routine practice. At pre…