Nishant R. Shah
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View article: Diagnostic Pitfall and Clinical Characteristics of Variant Versus Wild-Type Transthyretin Amyloid Cardiomyopathy in Asian Population: The Korean Nationwide Cohort Study
Diagnostic Pitfall and Clinical Characteristics of Variant Versus Wild-Type Transthyretin Amyloid Cardiomyopathy in Asian Population: The Korean Nationwide Cohort Study Open
A nationwide cohort of ATTR-CM exhibited less male predominance, a proportion of patients without increased LV wall thickness, and distinct characteristics of genetic mutations, compared to cohorts in other parts of the world. Our results …
View article: Cardiovascular Testing in the United States during the COVID-19 Pandemic: Volume Recovery and Worldwide Comparison
Cardiovascular Testing in the United States during the COVID-19 Pandemic: Volume Recovery and Worldwide Comparison Open
The reductions in cardiac testing during the early pandemic have recovered within a year to prepandemic baselines in the United States and NUHICs, while procedure volumes remain depressed in lower-income countries.Keywords: SPECT, Cardiac,…
View article: Two decade trends in cardiovascular disease outcomes and cardiovascular risk factors among US veterans living with HIV
Two decade trends in cardiovascular disease outcomes and cardiovascular risk factors among US veterans living with HIV Open
Coomprhensive data on temporal trends in cardiovascular disease (CVD) risk factors and outcomes in people living with HIV are limited. Using retrospective data on 50,284 US Veterans living with HIV (VLWH) who received care in the VA from 2…
View article: Appropriateness of Cardiovascular Imaging in the Initial Assessment of Possible Acute Coronary Syndrome in the Emergency Department
Appropriateness of Cardiovascular Imaging in the Initial Assessment of Possible Acute Coronary Syndrome in the Emergency Department Open
Patients presenting with chest pain and related symptoms account for over 6 million emergency department (ED) visits in the United States annually. However, less than 5% of these patients are ultimately diagnosed with acute coronary syndro…
View article: Cardiac MRI Findings in Male Patients with Acute Myocarditis in the Presence or Absence of COVID-19 Vaccination
Cardiac MRI Findings in Male Patients with Acute Myocarditis in the Presence or Absence of COVID-19 Vaccination Open
By comparing phenotypic clinical characteristics and cardiovascular magnetic resonance (CMR) findings in 14 patients with COVID-19 mRNA vaccine-associated myocarditis to 14 patients with acute myocarditis from other causes, we found that p…
View article: Specifying uniform eligibility criteria to strengthen causal inference studies of long-term outcomes of COVID-19
Specifying uniform eligibility criteria to strengthen causal inference studies of long-term outcomes of COVID-19 Open
Background Causal interpretation of findings from existing epidemiological studies on long-term clinical outcomes of coronavirus disease 2019 (COVID-19) may be limited by the choice of comparator (control) group. Objective We compare two a…
View article: Telehealth for Contraceptive Services During the COVID-19 Pandemic: Provider Perspectives
Telehealth for Contraceptive Services During the COVID-19 Pandemic: Provider Perspectives Open
The pandemic significantly impacted contraceptive health care delivery. Telehealth has sustained access to contraception in important ways, but has been accompanied by various challenges, including technological access and confidentiality.…
View article: Subcutaneous sarilumab for the treatment of hospitalized patients with moderate to severe COVID19 disease: A pragmatic, embedded randomized clinical trial
Subcutaneous sarilumab for the treatment of hospitalized patients with moderate to severe COVID19 disease: A pragmatic, embedded randomized clinical trial Open
Importance and objective The aim of this pragmatic, embedded, adaptive trial was to measure the effectiveness of the subcutaneous anti-IL-6R antibody sarilumab, when added to an evolving standard of care (SOC), for clinical management of i…
View article: Anticipating and Addressing Challenges During Implementation of Clinical Decision Support Systems
Anticipating and Addressing Challenges During Implementation of Clinical Decision Support Systems Open
Rachel Gold, PhD, MPH; Annie E. Larson, PhD; JoAnn M. Sperl-Hillen, MD; David Boston, MD; Christina R. Sheppler, PhD; John Heintzman, MD; Carmit McMullen, PhD; Mary Middendorf, BS; Deepika Appana, BS; Vijayakumar Thirumalai, BTech; Ann Rom…
View article: 517. Subcutaneous Sarilumab for the Treatment of Hospitalized patients with Moderate to Severe COVID19 Disease: A Pragmatic, Embedded, Multi-Center Randomized Clinical Trial
517. Subcutaneous Sarilumab for the Treatment of Hospitalized patients with Moderate to Severe COVID19 Disease: A Pragmatic, Embedded, Multi-Center Randomized Clinical Trial Open
Background The aim of this pragmatic, embedded adaptive trial was to measure the effectiveness of subcutaneous sarilumab in addition to an evolving standard of care for clinical management of inpatients with moderate to severe COVID-19 dis…
View article: Outcomes of coronavirus disease‐2019 among veterans with pre‐existing diagnosis of heart failure
Outcomes of coronavirus disease‐2019 among veterans with pre‐existing diagnosis of heart failure Open
Aims Pre‐existing cardiovascular disease in general and related risk factors have been associated with poor coronavirus disease‐2019 (COVID‐19) outcomes. However, data on outcomes of COVID‐19 among people with pre‐existing diagnosis of hea…
View article: Aortic Valve Calcification Is Associated with Future Cognitive Impairment
Aortic Valve Calcification Is Associated with Future Cognitive Impairment Open
Background: While an association between atherosclerosis and dementia has been identified, few studies have assessed the longitudinal relationship between aortic valve calcification (AVC) and cognitive impairment (CI). Objective: We sought…
View article: Association of poor housing conditions with COVID-19 incidence and mortality across US counties
Association of poor housing conditions with COVID-19 incidence and mortality across US counties Open
Counties with a higher percentage of households with poor housing had higher incidence of, and mortality associated with, COVID-19. These findings suggest targeted health policies to support individuals living in poor housing conditions sh…
View article: “Association of Poor Housing Conditions with COVID-19 Incidence and Mortality Across US Counties.”
“Association of Poor Housing Conditions with COVID-19 Incidence and Mortality Across US Counties.” Open
Objective Poor housing conditions have been linked with worse health outcomes and infectious spread in communities but its relationship with incidence and mortality of COVID-19 is unknown. Therefore, we undertook this study to determine th…
View article: Implementation of appropriate use criteria for cardiology tests and procedures: a systematic review and meta-analysis
Implementation of appropriate use criteria for cardiology tests and procedures: a systematic review and meta-analysis Open
Aims The American College of Cardiology appropriate use criteria (AUC) provide clinicians with evidence-informed recommendations for cardiac care. Adopting AUC into clinical workflows may present challenges, and there may be specific imple…
View article: Facility-Level Variation in Cardiac Stress Test Use Among Patients With Diabetes: Findings From the Veterans Affairs National Database
Facility-Level Variation in Cardiac Stress Test Use Among Patients With Diabetes: Findings From the Veterans Affairs National Database Open
Cardiac stress testing in patients with diabetes mellitus (DM) is a topic of much debate (1,2). The clinical heterogeneity and varied interpretation of atypical symptoms in this population may lead to significant variation in cardiac stres…