Dipty Singh
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View article: Influence Of Demographic Factors On Awareness Of Thyroid And Hypertension Management Among Pregnant Women
Influence Of Demographic Factors On Awareness Of Thyroid And Hypertension Management Among Pregnant Women Open
Background:Thyroid dysfunction and hypertensive disorders during pregnancy significantly contribute to maternal and fetal morbidity. Early awareness and preventive strategies can reduce complications, yet awareness levels may be influenced…
View article: Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss
Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss Open
During fertilization, spermatozoa contribute genetic and epigenetic factors such as chromatin packaged with protamines and histones; DNA methylome, non-coding RNAs, etc. Human sperm chromatin retains 5-15% nucleosomes which can play a key …
View article: Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss
Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss Open
Background: During fertilization, spermatozoa contribute genetic and epigenetic factors such as chromatin packaged with protamines and histones; DNA methylome, micro RNAs etc. Human sperm chromatin retains 5–15% nucleosomes which can play …
View article: Lead and calcium crosstalk tempted acrosome damage and hyperpolarization of spermatozoa: signaling and ultra-structural evidences
Lead and calcium crosstalk tempted acrosome damage and hyperpolarization of spermatozoa: signaling and ultra-structural evidences Open
Background Exposure of humans and animals to heavy metals is increasing day-by-day; thus, lead even today remains of significant public health concern. According to CDC, blood lead reference value (BLRV) ranges from 3.5 µg/dl to 5 μg/dl in…
View article: Impact of Maternal Gestational Methyl Donor Deficiency on Reproductive Development and Fertility of Mice Offspring
Impact of Maternal Gestational Methyl Donor Deficiency on Reproductive Development and Fertility of Mice Offspring Open
View article: DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss
DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss Open
Previously, we showed that DNA methylation defects in spermatozoa from male partners of couples undergoing recurrent pregnancy loss (RPL) could be a contributing paternal factor. In the present study, we aimed to determine whether the meth…
View article: DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss
DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss Open
Previously, we showed that DNA methylation defects in spermatozoa from male partners of couples undergoing recurrent pregnancy loss (RPL) could be a contributing paternal factor. In the present study, we aimed to determine whether the meth…
View article: Whole genome bisulfite sequencing of sperm reveals differentially methylated regions in male partners of idiopathic recurrent pregnancy loss cases
Whole genome bisulfite sequencing of sperm reveals differentially methylated regions in male partners of idiopathic recurrent pregnancy loss cases Open
View article: pH Stress Mediated Alteration in Protein Composition and Reduction in Cytotoxic Potential of Gardnerella vaginalis Membrane Vesicles
pH Stress Mediated Alteration in Protein Composition and Reduction in Cytotoxic Potential of Gardnerella vaginalis Membrane Vesicles Open
The vagina of healthy women is predominantly colonized by lactobacilli but it also harbors a limited proportion of certain anaerobes such as Gardnerella vaginalis . An increase in G. vaginalis along with other anaerobes on account of pertu…
View article: Collapsed mitochondrial cristae in goat spermatozoa due to mercury result in lethality and compromised motility along with altered kinematic patterns
Collapsed mitochondrial cristae in goat spermatozoa due to mercury result in lethality and compromised motility along with altered kinematic patterns Open
View article: Simulation of rabbit model to study the effect of 131Iodine and radioprotectant on salivary gland ultrastructure
Simulation of rabbit model to study the effect of 131Iodine and radioprotectant on salivary gland ultrastructure Open
View article: Causes and consequences of sperm mitochondrial dysfunction
Causes and consequences of sperm mitochondrial dysfunction Open
Mitochondria have multiple functions, including synthesis of adenine triphosphate, production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis. Mitochondria have a significant contribution in regulating the vario…
View article: Is there plagiarism in the most influential publications in the field of andrology?
Is there plagiarism in the most influential publications in the field of andrology? Open
Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology articles. A total o…
View article: Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking
Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking Open
Outcome of host-pathogen encounter is determined by the complex interplay between protective bacterial and host defense strategies. This complexity further amplifies with the existence of cell-to-cell phenotypic heterogeneity in pathogens …
View article: Bisphenol A-induced ultrastructural changes in the testes of common marmoset
Bisphenol A-induced ultrastructural changes in the testes of common marmoset Open
Background & objectives: Bisphenol A (BPA) is an endocrine disruptor that is widely used in the manufacture of polycarbonate plastics, epoxy resins and dental sealants. It is known to have adverse effects on spermatogenesis in rodents. Thi…
View article: Embryonic Zebrafish Model - A Well-Established Method for Rapidly Assessing the Toxicity of Homeopathic Drugs - Toxicity Evaluation of Homeopathic Drugs Using Zebrafish Embryo Model -
Embryonic Zebrafish Model - A Well-Established Method for Rapidly Assessing the Toxicity of Homeopathic Drugs - Toxicity Evaluation of Homeopathic Drugs Using Zebrafish Embryo Model - Open
Our findings clearly demonstrate that no toxic effects were observed for these three homeopathic drugs at the potencies and exposure times used in this study. The embryonic zebrafish model is recommended as a well-established method for ra…