Nitish A. Kulkarni
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View article: OR29-06 Liver Receptor Homolog 1 (LRH-1) regulates myeloid immune cell functions, revealing a new approach to cancer therapy
OR29-06 Liver Receptor Homolog 1 (LRH-1) regulates myeloid immune cell functions, revealing a new approach to cancer therapy Open
Disclosure: Y. Wang: None. N.A. Kulkarni: None. B. Duong: None. N. Krawczynska: None. S.V. Bendre: None. C.P. Schane: None. E. Weisser: None. L. Kockaya: None. Y. Fei: None. A. Das Gupta: None. H. Vidana Gamage: None. A.T. Nelson: None. S.…
View article: Fungal immunization potentiates CD4+ T cell-independent cDC2 responses for cross-presentation
Fungal immunization potentiates CD4+ T cell-independent cDC2 responses for cross-presentation Open
The incidence rates of fungal infections are increasing, especially in immunocompromised individuals without an FDA-approved vaccine. Accumulating evidence suggests that T cells are instrumental in providing fungal immunity. An apt stimula…
View article: Lung Immunity to Fungal Infections by Macrophages: Mechanisms and Implications
Lung Immunity to Fungal Infections by Macrophages: Mechanisms and Implications Open
Pulmonary pathogenic fungi cause severe to fatal disseminated infections, especially in immunocompromised patients. Alveolar macrophages form an essential early innate cellular barrier implicated in immunity to pulmonary mycoses. The compl…
View article: Advances in Dendritic-Cell-Based Vaccines against Respiratory Fungal Infections
Advances in Dendritic-Cell-Based Vaccines against Respiratory Fungal Infections Open
Ever since the discovery of dendritic cells by Ralph Steinman and Zanvil Cohn in 1973, it is increasingly evident that dendritic cells are integral for adaptive immune responses, and there is an undeniable focus on them for vaccines develo…
View article: Advances in Dendritic Cell-Based Vaccines Against Respiratory Fungal Infections
Advances in Dendritic Cell-Based Vaccines Against Respiratory Fungal Infections Open
Ever since the discovery of dendritic cells by Ralph Steinman and Zanvil Cohn in 1973, it is increasingly evident that dendritic cells are integral for adaptive immune responses, and there is an undeniable focus on them for vaccines develo…
View article: Time Dependent Impact of Reactive Oxidants on Seminal Attributes, Mitochondrial Membrane Potential, Lipid Peroxidation and Capacitation-Like Changes of Karan-Fries (KF) Bulls During Cryopreservation
Time Dependent Impact of Reactive Oxidants on Seminal Attributes, Mitochondrial Membrane Potential, Lipid Peroxidation and Capacitation-Like Changes of Karan-Fries (KF) Bulls During Cryopreservation Open
BACKGROUND: Cryopreservation of semen is a valuable technique; however, it is also known to be detrimental to the structure of spermatozoa and fertility due to cryo-injury and subsequent generation of reactive oxidants. OBJECTIVE: To deter…