NJ Loxton
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View article: Polygenic risk moderates the causal association between reward-related impulsivity and adolescent alcohol use
Polygenic risk moderates the causal association between reward-related impulsivity and adolescent alcohol use Open
Aim: Impulsivity is a robust predictor of alcohol use in adolescence. There is little evidence on the causal mechanisms through which it influences drinking or how they are affected by key social and genetic risk factors. This study invest…
View article: Direct, indirect and epistatic associations of reward system genes with heroin dependence
Direct, indirect and epistatic associations of reward system genes with heroin dependence Open
Objective: Genes encoding molecular pathways of the reward system are implicated in both addiction and impulsivity. A complex interplay of these genes is likely to contribute to the risk and perpetuation of addiction, both directly and ind…